Naxitamab

West Conshohocken, PA, Sept. 16, 2025 (GLOBE NEWSWIRE) -- SERB Pharmaceuticals (“SERB”), a global specialty pharmaceutical company focused on rare diseases and medical emergencies, today announced the successful completion of its acquisition of Y-mAbs Therapeutics, Inc. (“Y-mAbs”), a commercial-stage biopharmaceutical company focused on the development and commercialization of antibody-based therapeutics for the treatment of cancer. “We are excited to welcome Y-mAbs into SERB. The acquisition strengthens our Rare Oncology portfolio with the addition of Danyelza® (naxitamab-gqgk) and brings deep oncology expertise that will help us to expand our partnerships with the US oncology community and to advance treatments for rare and hard-to-treat cancers”, said Vanessa Wolfeler, Chief Executive Officer of SERB. “This marks a significant step forward in delivering on SERB’s growth strategy and vision, but more importantly, it allows us to help more children and families facing pediatric cancers.” Completion of Tender Offer and Transaction Details The tender offer period, initiated on August 18, 2025, expired at one minute following 11:59 p.m., Eastern Time, on September 15, 2025. The conditions of the tender offer having been satisfied, SERB has accepted all such tendered shares for $8.60 per share, and following a statutory merger under Section 251(h) of the Delaware General Corporation Law on September 16, 2025, Y-mAbs became a wholly owned subsidiary of SERB and was delisted from the Nasdaq Global Select Market. All remaining Y-mAbs shares that were not tendered in the tender offer will be converted into the right to receive the same $8.60 per share in cash paid for shares that were tendered in the tender offer. About Danyelza® (naxitamab-gqgk) Danyelza® (naxitamab-gqgk) is indicated, in combination with granulocyte-macrophage colony-stimulating factor (“GM-CSF”), for the treatment of pediatric patients one year of age and older and adult patients with relapsed or refractory high-risk neuroblastoma in the bone or bone marrow who have demonstrated a partial response, minor response, or stable disease to prior therapy. This indication was approved under accelerated approval based on overall response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefits in a confirmatory trial. Danyelza® includes a Boxed Warning for serious infusion-related reactions, such as cardiac arrest and anaphylaxis, and neurotoxicity, such as severe neuropathic pain and transverse myelitis. See full Prescribing Information for complete Boxed Warning and other important safety information here. Danyelza® is currently not approved for the treatment of osteosarcoma in any jurisdiction. About SERB Pharmaceuticals SERB is a global specialty pharmaceutical company with a growing portfolio of medicines for rare emergency medicine, rare diseases, and CBRN preparedness. For over 30 years we have made treating complex and life-threatening conditions possible, supporting clinicians, healthcare systems and governments while offering hope to patients and their families. SERB is a leading provider of essential acute care medicines, addressing unmet medical needs and supplying antidotes and medical countermeasures for chemical, biological, radiological and nuclear (CBRN) risks. As a fully integrated company, we have the experience and capabilities to acquire, develop, and manufacture our medicines to the highest standards, and make them available worldwide through our secure supply chain. Learn more at https://SERB.com Forward-Looking Statements This press release contains forward-looking statements that involve risks and uncertainties relating to future events and the future performance of Y-mAbs and SERB, including statements relating to SERB’s acquisition of Y-mAbs and other statements that are not historical facts. The forward-looking statements contained in this release are based on current expectations and assumptions that are subject to risks and uncertainties which may cause actual results to differ materially from the forward-looking statements. These statements may contain words such as “may,” “will,” “would,” “could,” “expect,” “anticipate,” “intend,” “plan,” “believe,” “estimate,” “project,” “seek,” “should,” “strategy,” “future,” “opportunity,” “potential” or other similar words and expressions indicating future results. Risks that may cause these forward-looking statements to be inaccurate include, without limitation: risks related to the parties’ ability to realize the anticipated benefits of the acquisition, including the possibility that the expected benefits from the acquisition will not be realized or will not be realized within the expected time period and that Y-mAbs and SERB will not be integrated successfully or that such integration may be more difficult, time-consuming or costly than expected; the effects of the transaction on relationships with employees, customers, suppliers, other business partners or governmental entities; negative effects of this announcement; unknown or inestimable liabilities; the risk of litigation and/or regulatory actions related to the transaction; obtaining and maintaining adequate coverage and reimbursement for products; the costly and time-consuming pharmaceutical product development process and the uncertainty of clinical success, including risks related to failure or delays in successfully initiating or completing clinical trials and assessing patients; global economic, financial, and healthcare system disruptions and the current and potential future negative impacts to the parties’ business operations and financial results; the sufficiency of the parties’ cash flows and capital resources; the parties’ ability to achieve targeted or expected future financial performance and results and the uncertainty of future tax, accounting and other provisions and estimates; and other risks and uncertainties affecting Y-mAbs and SERB, including those described from time to time under the caption “Risk Factors” and elsewhere in YmAbs’ filings and reports with the U.S. Securities and Exchange Commission (the “SEC”), including Y-mAbs’ Annual Report on Form 10-K for the fiscal year ended December 31, 2024 and Quarterly Reports on Form 10-Q for the quarterly periods ended March 31, 2025 and June 30, 2025 and any subsequent filings made by either party with the SEC, available on the SEC’s website at www.sec.gov. Any forward-looking statements are made based on the current beliefs and judgments of Y-mAbs’ and SERB’s management, and the reader is cautioned not to rely on any forward-looking statements made by Y-mAbs or SERB. Except as required by law, Y-mAbs and SERB do not undertake any obligation to update (publicly or otherwise) any forward-looking statement, including without limitation any financial projection or guidance, whether as a result of new information, future events, or otherwise.

Reported Total Revenues of $19.5 million for the second quarter of 2025, exceeding the high end of the Company’s guidance range of between $17 million and $19 millionSERB Pharmaceuticals to acquire Y-mAbs in $412.0 million transaction; transaction expected to close by the fourth quarter of 2025, subject to completion of tender offer and other customary conditionsAs of June 30, 2025, cash and cash equivalents were $62.3 millionIn light of the pending transaction, Y-mAbs will not be holding a webcast and conference call to discuss its second quarter 2025 results PRINCETON, N.J., Aug. 08, 2025 (GLOBE NEWSWIRE) -- Y-mAbs Therapeutics, Inc. (the “Company” or “Y-mAbs”) (Nasdaq: YMAB), a commercial-stage biopharmaceutical company focused on the development and commercialization of novel radioimmunotherapy and antibody-based therapeutic products for the treatment of cancer, today reported financial results for the second quarter ended June 30, 2025. Recent Transaction Announcement with SERB On August 5, 2025, Y-mAbs announced it has entered into a definitive agreement with affiliated entities of SERB Pharmaceuticals (“SERB”), under which SERB, a global specialty pharmaceutical company, agreed to acquire Y-mAbs in a transaction at an equity value of $412.0 million. The transaction was unanimously approved by the Y-mAbs Board of Directors. Under the terms of the merger agreement, SERB is obligated to commence a tender offer by August 19, 2025 to purchase all outstanding shares of Y-mAbs for $8.60 per share in cash, representing a 105% premium to Y-mAbs’ closing share price on August 4, 2025, the last full trading day prior to the transaction announcement.The transaction is expected to close by the fourth quarter of 2025, assuming a majority of outstanding Y-mAbs shares are tendered into, and not withdrawn from, the tender offer, and subject to the satisfaction of customary conditions, including the receipt of a majority of Y-mAbs shares in the tender offer and expiration or termination of the applicable waiting period under the Hart-Scott-Rodino Antitrust Improvements Act. Financial Results Revenues Total revenues for the quarter ended June 30, 2025 were $19.5 million, which was a 14% decrease from the $22.8 million of total revenues for the quarter ended June 30, 2024, driven by a $2.9 million decrease in Ex-U.S. DANYELZA® net product revenues and a $0.9 million decrease in U.S. DANYELZA net product revenues, partially offset by a $0.5 million increase related to license revenue recognized in the three months ended June 30, 2025. Total DANYELZA net product revenues for the quarter ended June 30, 2025 were $19.0 million, which was a 17% decrease over $22.8 million total DANYELZA net product revenues for the quarter ended June 30, 2024. Total revenues for the six months ended June 30, 2025 were $40.4 million, which was a 5% decrease from the $42.7 million of total revenues for the six months ended June 30, 2024, driven by a $6.1 million decrease in U.S DANYELZA net product revenues, partially offset by a $3.8 million increase in Ex-U.S. DANYELZA net product revenues. The total revenues in the six months ended June 30, 2025 and 2024 include $0.5 million license revenue, respectively. The Company’s U.S. DANYELZA net product revenues for the quarter ended June 30, 2025 were $14.3 million, representing a decrease of 6% from the same period in 2024. The decline in the U.S. DANYELZA net product revenues was driven by declining patient volume due to enrollments in clinical studies and competition in the three months ended June 30, 2025. The Company’s Ex-U.S. DANYELZA net product revenues for the quarter ended June 30, 2025 were $4.7 million, representing a decrease of $2.9 million from the same period in 2024. Ex-U.S. DANYELZA net product revenues include $2.1 million from Western Europe and $3.4 million from Eastern Asia for the three months ended June 30, 2024, which was a result of stocking orders from Western Europe and Eastern Asia in 2024. The Company did not have any stocking orders from Western Europe or Eastern Asia in the three months ended June 30, 2025. The decrease in Ex-U.S. DANYELZA net product revenues was partially offset by a $2.0 million increase in DANYELZA net product revenues in Western Asia, where a named patient program launched in Turkey in late 2024. During the three and six months ended June 30, 2025, the Company recognized $0.5 million license revenue, which was earned in prior periods, in connection with sales-based milestone achievements by our partner in Israel. There was no license revenue in the three months ended June 30, 2024. During the six months ended June 30, 2024, the Company had license revenues of $0.5 million, which included license revenue from the Latin America distribution partner, Adium, related to price approval for DANYELZA in Brazil from the Brazilian Medicines Market Regulation Chamber. Cost of Goods Sold Cost of goods sold was $2.7 million and $3.0 million for the three months ended June 30, 2025 and 2024, respectively. The decrease in cost of goods sold in the three months ended June 30, 2025 compared to the same period in 2024 was primarily driven by decreased sales. Cost of goods sold was $5.7 million and $5.1 million for the six months ended June 30, 2025 and 2024, respectively. The increase in cost of goods sold in the six months ended June 30, 2025 compared to the same period in 2024 was primarily driven by increased cost of production. Gross Profit Gross profit stayed consistent at $16.8 million and $19.8 million for the three months ended June 30, 2025 and 2024, respectively. Gross margins were relatively flat at 86% and 87% for the three months ended June 30, 2025 and 2024, respectively. Gross profit was $34.8 million and $37.6 million for the six months ended June 30, 2025 and 2024, respectively. Gross margins were 86% and 88% for the six months ended June 30, 2025 and 2024, respectively. The gross margin decreased primarily due to increased cost of production and lower product sales to Western Europe, where product sales generally have higher gross margin. Operating Costs and Expenses Research and Development Research and development expenses were $11.1 million and $12.3 million for the three months ended June 30, 2025 and 2024, respectively. The $1.2 million decrease in research and development expenses was primarily driven by a decrease of $0.9 million in personnel and stock-based compensation costs which was primarily related to our business realignment announced in January 2025. Research and development expenses were $22.5 million and $25.6 million for the six months ended June 30, 2025 and 2024, respectively. The $3.1 million decrease in research and development expenses was primarily driven by a $1.8 million decrease in personnel and stock-based compensation costs, which was primarily related to our business realignment announced in January 2025, and a total $0.4 million decrease in clinical trials and outsourced research and supplies due to the timing of completion in our GD2-SADA program and investment in our ongoing SADA PRIT programs. Selling, General, and Administrative Selling, general, and administrative expenses were $11.3 million and $17.2 million for the three months ended June 30, 2025 and 2024, respectively. The $5.9 million decrease in selling, general and administrative expenses was primarily attributable to a net impact of $3.8 million related to litigation settlements during the three months ended June 30, 2024 and a $1.7 million decrease in legal expenses. Selling, general, and administrative expenses were $24.4 million and $28.7 million for the six months ended June 30, 2025 and 2024, respectively. The $4.3 million decrease in selling, general, and administrative expenses was primarily attributable to a net impact of $3.8 million related to litigation settlements in the six months ended June 30, 2024, as noted above. Interest and Other Income Interest and other income were $2.3 million and $0.6 million for the three months ended June 30, 2025 and 2024, respectively. Interest and other income increased by $1.7 million primarily due to $2.0 million of foreign currency transaction gains in the three months ended June 30, 2025, partially offset by a $0.3 million decrease in interest earned on cash and cash equivalents. Interest and other income were $3.7 million and $1.1 million for the six months ended June 30, 2025 and 2024, respectively. Interest and other income increased by $2.6 million primarily due to $3.3 million of foreign currency transaction gains, partially offset by a $0.7 million decrease in interest earned on cash and cash equivalents. Net Loss Y-mAbs reported a net loss for the quarter ended June 30, 2025, of $3.2 million, or ($0.07) per basic and diluted share, compared to a net loss of $9.2 million, or ($0.21) per basic and diluted share, for the quarter ended June 30, 2024. The decrease in net loss for the quarter ended June 30, 2025 was primarily driven by the above noted $3.8 million in litigation settlements in the quarter end June 30, 2024 and the favorable impact of $2.0 million of foreign currency transaction gains in the quarter ended June 30, 2025. Cash and Cash Equivalents As of June 30, 2025, Y-mAbs had approximately $62.3 million in cash and cash equivalents. The Company continues its efforts to be capital efficient in its operations. In light of the pending transaction, Y-mAbs will not be holding a webcast and conference call to discuss its second quarter 2025 results. About Y-mAbs Y-mAbs is a commercial-stage biopharmaceutical company focused on the development and commercialization of novel, radioimmunotherapy and antibody-based therapeutic cancer products. The Company’s broad and advanced commercial product pipeline includes the anti-GD2 therapy DANYELZA® (naxitamab-gqgk), the first FDA-approved treatment for patients with relapsed or refractory high-risk neuroblastoma in the bone or bone marrow after a partial response, minor response, or stable disease to prior therapy. The Company’s technologies include its investigational Self-Assembly DisAssembly (“SADA”) Pretargeted Radioimmunotherapy Platform (“PRIT”) and bispecific antibodies generated using the Y-BiClone platform. Forward-Looking Statements This press release contains forward-looking statements that involve risks and uncertainties relating to future events and the future performance of Y-mAbs and SERB, including statements relating to the ability to complete and the timing of completion of the transactions contemplated by the Agreement and Plan of Merger dated as of August 4, 2025 by and among Y-mAbs, SERB, and the other parties thereto (the “Merger Agreement”), including the anticipated occurrence, manner and timing of the proposed tender offer, the parties’ ability to satisfy the conditions to the consummation of the tender offer and the other conditions to the consummation of the subsequent merger set forth in the Merger Agreement, the possibility of any termination of the Merger Agreement, and the prospective benefits of the proposed transaction; and other statements that are not historical facts. The forward-looking statements contained in this release are based on current expectations and assumptions that are subject to risks and uncertainties which may cause actual results to differ materially from the forward-looking statements. These statements may contain words such as “may,” “will,” “would,” “could,” “expect,” “anticipate,” “intend,” “plan,” “believe,” “estimate,” “project,” “seek,” “should,” “strategy,” “future,” “opportunity,” “potential” or other similar words and expressions indicating future results. Risks that may cause these forward-looking statements to be inaccurate include, without limitation: uncertainties as to the timing of the tender offer; uncertainties as to how many of Y-mAbs’ stockholders will tender their stock in the offer; the possibility that competing offers or acquisition proposals will be made; the possibility that various closing conditions for the transaction may not be satisfied or waived, including that a governmental entity may prohibit, delay, or refuse to grant approval for the consummation of the transaction (or only grant approval subject to adverse conditions or limitations); the difficulty of predicting the timing or outcome of regulatory approvals or actions, if any; the occurrence of any event, change or other circumstance that could give rise to the termination of the Merger Agreement; the possibility that the transaction does not close; risks related to the parties’ ability to realize the anticipated benefits of the proposed transaction, including the possibility that the expected benefits from the proposed acquisition will not be realized or will not be realized within the expected time period and that Y-mAbs and SERB will not be integrated successfully or that such integration may be more difficult, time-consuming or costly than expected; the effects of the transaction on relationships with employees, customers, suppliers, other business partners or governmental entities; negative effects of this announcement or the consummation of the proposed transaction on the market price of Y-mAbs’ common stock and/or Y-mAbs’ operating results; significant transaction costs; unknown or inestimable liabilities; the risk of litigation and/or regulatory actions related to the proposed transaction; SERB’s ability to fund the proposed transaction; obtaining and maintaining adequate coverage and reimbursement for products; the time-consuming and uncertain regulatory approval process; the costly and time-consuming pharmaceutical product development process and the uncertainty of clinical success, including risks related to failure or delays in successfully initiating or completing clinical trials and assessing patients; global economic, financial, and healthcare system disruptions and the current and potential future negative impacts to the parties’ business operations and financial results; the sufficiency of the parties’ cash flows and capital resources; the parties’ ability to achieve targeted or expected future financial performance and results and the uncertainty of future tax, accounting and other provisions and estimates; and other risks and uncertainties affecting Y-mAbs and SERB, including those described from time to time under the caption “Risk Factors” and elsewhere in Y-mAbs’ filings and reports with the U.S. Securities and Exchange Commission (the “SEC”), including Y-mAbs’ Annual Report on Form 10-K for the fiscal year ended December 31, 2024 and Quarterly Reports on Form 10-Q for the quarterly periods ended March 31, 2025 and June 30, 2025, as well as the Tender Offer Statement on Schedule TO and related tender offer documents to be filed by SERB and its acquisition subsidiary, and the Solicitation/Recommendation Statement on Schedule 14D-9 to be filed by Y-mAbs. Any forward-looking statements are made based on the current beliefs and judgments of Y-mAbs’ and SERB’s management, and the reader is cautioned not to rely on any forward-looking statements made by Y-mAbs or SERB. Except as required by law, Y-mAbs and SERB do not undertake any obligation to update (publicly or otherwise) any forward-looking statement, including without limitation any financial projection or guidance, whether as a result of new information, future events, or otherwise. DANYELZA® and Y-mAbs® are registered trademarks of Y-mAbs Therapeutics, Inc. Y-MABS THERAPEUTICS, INC.Consolidated Balance Sheets(unaudited)(In thousands, except share and per share data) June 30, December 31, 2025 2024ASSETS CURRENT ASSETS Cash and cash equivalents $62,293 $67,234 Accounts receivable, net 15,740 19,688 Inventories 9,719 7,214 Other current assets 4,035 4,373 Total current assets 91,787 98,509 Property and equipment, net 269 42 Operating lease right-of-use assets 3,109 817 Intangible assets, net 2,177 2,276 Inventories, long-term 19,223 17,772 Other assets 646 488 TOTAL ASSETS $117,211 $119,904 LIABILITIES AND STOCKHOLDERS’ EQUITY LIABILITIES Accounts payable $7,571 $6,662 Accrued liabilities 14,888 16,406 Operating lease liabilities, current portion 486 630 Total current liabilities 22,945 23,698 Accrued milestones 3,200 3,200 Operating lease liabilities, long-term portion 2,638 190 Other liabilities 935 812 TOTAL LIABILITIES 29,718 27,900 STOCKHOLDERS’ EQUITY Preferred stock, $0.0001 par value, 5,500,000 shares authorized and none issued at June 30, 2025 and December 31, 2024 — — Common stock, $0.0001 par value, 100,000,000 shares authorized at June 30, 2025 and December 31, 2024; 45,438,420 and 44,988,313 shares issued and outstanding at June 30, 2025 and December 31, 2024, respectively 5 4 Additional paid-in capital 583,671 576,872 Accumulated other comprehensive income (612) 2,264 Accumulated deficit (495,571) (487,136)TOTAL STOCKHOLDERS’ EQUITY 87,493 92,004 TOTAL LIABILITIES AND STOCKHOLDERS’ EQUITY $117,211 $119,904 Y-MABS THERAPEUTICS, INC.Consolidated Statements of Net Loss and Comprehensive Loss(unaudited)(In thousands, except share and per share data) Three months ended June 30, Six months ended June 30, 2025 2024 2025 2024 REVENUES Net product revenue $19,025 $22,798 $39,929 $42,229 License revenue 500 — 500 500 Total revenues 19,525 22,798 40,429 42,729 COST OF GOODS SOLD 2,662 3,014 5,663 5,111 GROSS PROFIT 16,863 19,784 34,766 37,618 OPERATING COSTS AND EXPENSES License royalties 50 — 50 50 Research and development 11,104 12,341 22,463 25,608 Selling, general, and administrative 11,313 17,232 24,400 28,657 Total operating costs and expenses 22,467 29,573 46,913 54,315 Loss from operations (5,604) (9,789) (12,147) (16,697)OTHER INCOME, NET Interest and other income 2,372 640 3,723 1,079 LOSS BEFORE INCOME TAXES (3,232) (9,149) (8,424) (15,618)Provision for income taxes 7 100 12 260 NET LOSS $(3,239) $(9,249) $(8,436) $(15,878)Other comprehensive income/(loss) Foreign currency translation (2,013) 199 (2,876) 598 COMPREHENSIVE LOSS $(5,252) $(9,050) $(11,312) $(15,280)Net loss per share attributable to common stockholders, basic and diluted $(0.07) $(0.21) $(0.19) $(0.36)Weighted average common shares outstanding, basic and diluted 45,318,028 44,022,356 45,212,065 43,900,639 Y-MABS THERAPEUTICS, INC.Consolidated Statements of Cash Flows(unaudited)(In thousands) Six months ended June 30, 2025 2024CASH FLOWS FROM OPERATING ACTIVITIES Net loss $(8,436) $(15,878)Adjustments to reconcile net loss to net cash used in operating activities: Depreciation and amortization 124 312 Stock-based compensation 6,243 7,285 Foreign currency transactions (2,752) 724 Changes in assets and liabilities: Accounts receivable, net 3,948 263 Inventories (2,394) (3,433)Insurance recovery receivable related to legal settlement — (16,025)Other current assets 338 2,712 Inventories, long-term (1,451) (1,084)Other assets (158) 115 Accounts payable 3,654 3,406 Accrued liabilities and other (4,376) (1,226)Accrued legal settlement — 19,650 NET CASH USED IN OPERATING ACTIVITIES (5,260) (3,179)NET CASH USED IN INVESTING ACTIVITIES Purchase of property and equipment (127) — NET CASH USED IN INVESTING ACTIVITIES (127) — CASH FLOWS FROM FINANCING ACTIVITIES Proceeds from exercised stock options 446 2,346 NET CASH PROVIDED BY FINANCING ACTIVITIES 446 2,346 Effect of exchange rates on cash and cash equivalents — 2 NET DECREASE IN CASH AND CASH EQUIVALENTS (4,941) (831)Cash and cash equivalents at the beginning of period 67,234 78,637 Cash and cash equivalents at the end of period $62,293 $77,806 SUPPLEMENTAL DISCLOSURE OF NON-CASH ACTIVITIES Right-of-use assets obtained in exchange for lease obligations $2,560 $320 Property and equipment purchase in accrued liabilities and other $118 $— Y-MABS THERAPEUTICS, INC.Selected Financial Information by Reportable Segment (unaudited)(In thousands) Three Months Ended June 30, 2025 2024 DANYELZA RIT Total DANYELZA RIT Total REVENUES Net product revenue $19,025 $— $19,025 $22,798 $— $22,798 License revenue 500 — 500 — — — Total revenues 19,525 — 19,525 22,798 — 22,798 COST OF GOODS SOLD 2,662 — 2,662 3,014 — 3,014 OPERATING COSTS AND EXPENSES License royalties 50 — 50 — — — Research and development 5,444 5,239 10,683 5,185 5,835 11,020 Selling, general, and administrative 3,865 417 4,282 5,205 — 5,205 Segment profit/(loss) from operations $7,504 $(5,656) $1,848 $9,394 $(5,835) $3,559 Corporate and unallocated expenses - Research and development 421 1,321 Corporate and unallocated expenses - Selling, general, and administrative 7,031 12,027 Consolidated Loss from Operations (5,604) (9,789)OTHER INCOME, NET Corporate and unallocated expenses - Interest and other income 2,372 640 CONSOLIDATED LOSS BEFORE INCOME TAXES $(3,232) $(9,149) Six Months Ended June 30, 2025 2024 DANYELZA RIT Total DANYELZA RIT Total REVENUES Net product revenue $39,929 $— $39,929 $42,229 $— $42,229 License revenue 500 — 500 500 — 500 Total revenues 40,429 — 40,429 42,729 — 42,729 COST OF GOODS SOLD 5,663 — 5,663 5,111 — 5,111 OPERATING COSTS AND EXPENSES License royalties 50 — 50 50 — 50 Research and development 10,370 10,935 21,305 10,594 11,876 22,470 Selling, general, and administrative 8,021 828 8,849 8,904 — 8,904 Segment profit/(loss) from operations $16,325 $(11,763) $4,562 $18,070 $(11,876) $6,194 Corporate and unallocated expenses - Research and development 1,158 3,138 Corporate and unallocated expenses - Selling, general, and administrative 15,551 19,753 Consolidated Loss from Operations (12,147) (16,697)OTHER INCOME, NET Corporate and unallocated expenses - Interest and other income 3,723 1,079 CONSOLIDATED LOSS BEFORE INCOME TAXES $(8,424) $(15,618) Investor Contact: Courtney Dugan VP, Head of Investor Relations cdu@ymabs.com