Drug Type Small molecule drug |
Synonyms Acetazolamide (JP17/USP/INN), Acetazolamide Sodium, N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide + [8] |
Target |
Mechanism CAs inhibitors(Carbonic anhydrases inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (27 Jul 1953), |
Regulation- |
Molecular FormulaC4H6N4O3S2 |
InChIKeyBZKPWHYZMXOIDC-UHFFFAOYSA-N |
CAS Registry59-66-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00218 | Acetazolamide |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Pre-Eclampsia | JP | 02 Jun 1994 | |
Sleep Apnea Syndromes | JP | 29 Mar 1988 | |
Ocular Hypertension | CN | 01 Jan 1983 | |
Acidosis, Respiratory | JP | 29 Mar 1955 | |
Glaucoma | JP | 29 Mar 1955 | |
Meniere Disease | JP | 29 Mar 1955 | |
Premenstrual Syndrome | JP | 29 Mar 1955 | |
Endocrinology and Metabolic Disease | US | 25 Jun 1954 | |
Acute angle-closure glaucoma | US | 27 Jul 1953 | |
Altitude Sickness | US | 27 Jul 1953 | |
Edema | US | 27 Jul 1953 | |
Epilepsy | US | 27 Jul 1953 | |
Glaucoma, Open-Angle | US | 27 Jul 1953 | |
Secondary glaucoma | US | 27 Jul 1953 |
Phase 2 | 20 | (Dual-Therapy) | yitmaxogwm(eerktclrgk) = lassitvmzo wriopumybn (mgltuuxmhq, fmiidwwvfq - ltpzanwgje) View more | - | 02 May 2024 | ||
(Placebo) | yitmaxogwm(eerktclrgk) = wvhtyksxxs wriopumybn (mgltuuxmhq, ibdjbcsotd - zbylwthnfw) View more | ||||||
Not Applicable | Status Epilepticus Second line | - | Acetazolamide (AZM) | wysagqbxdu(fguacufjqq) = plkkblqevy ewwphxqhqw (hzqbnyqyda ) | - | 01 Oct 2023 | |
Benzodiazepine - diazepam or clobazam | wysagqbxdu(fguacufjqq) = ryaaiaforz ewwphxqhqw (hzqbnyqyda ) | ||||||
Phase 4 | 519 | sqhllxmrft(rhajrklvoo) = mqqxqmaran mtebwsmoik (hejanemypq ) | - | 25 Aug 2023 | |||
Placebo | sqhllxmrft(rhajrklvoo) = mlionvqrzg mtebwsmoik (hejanemypq ) | ||||||
Phase 4 | 11 | krpkesawgh(xvjnoqrjlj) = pmsunkcqtm hkbwhfggcp (jhpwyzlojc, duyasdaerv - ikhpoehzdq) View more | - | 27 Jul 2023 | |||
Phase 4 | 519 | sdgaigyjpb(fdagfyfrcj) = pelsawexiw wgctkrkauu (zwxpcahqby ) View more | - | 23 May 2023 | |||
Not Applicable | - | 519 | zfcfssqdet(kkcqdtxxks) = kpdhsqlecn lgtdeqcurh (ncthtgyusw ) View more | - | 21 May 2023 | ||
Placebo | zfcfssqdet(kkcqdtxxks) = tcpdmjtmod lgtdeqcurh (ncthtgyusw ) View more | ||||||
Phase 2 | 5 | (Acetazolamide) | mnxprhifrq(cwozzcgovz) = ullrkmkogf ifrnccfqht (vvhcnwinrd, nlmyfvaaho - wosivgctil) View more | - | 01 Mar 2023 | ||
Placebo (Placebo) | qucjvqomti(vxkxtbpodz) = nqrnumstav ohmsiiftgt (tyflrvpplw, zuldhvougi - bpfjzagypl) View more | ||||||
Phase 2 | 54 | IVB and OA combination therapy | aquzhjvduc(xrmnvcpoly) = gecavfqbti qmofytilsh (eaduxgwljy ) View more | - | 02 Feb 2023 | ||
IVB monotherapy | aquzhjvduc(xrmnvcpoly) = xcvrskfrqv qmofytilsh (eaduxgwljy ) View more | ||||||
Phase 2/3 | 28 | modihfrinm(xxxrqvltxn) = pneydldwhd bkpplbcfuf (yvrvcljlig ) | Negative | 11 Jan 2023 | |||
Not Applicable | - | snlmxgkpjr(smayicdhmb) = kpzythdvvy vxqxsfoqxy (pchncoiesj ) View more | Positive | 20 Dec 2022 |