Drug Type Small molecule drug |
Synonyms 2-chloroethyl-3-sarcosinamide-1-nitrosourea, Sarmustine, SarNU + [2] |
Target |
Mechanism DNA inhibitors(DNA inhibitors), DNA alkylating agents |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC6H11ClN4O3 |
InChIKeyHYHJFNXFVPGMBI-UHFFFAOYSA-N |
CAS Registry81965-43-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Recurrent Malignant Glioma | Phase 2 | CA | 10 Jan 2002 | |
Metastatic Colorectal Carcinoma | Phase 2 | CA | 30 Oct 2001 | |
Colorectal Cancer | Phase 2 | CA | - | |
Glioma | Phase 2 | CA | - | |
Glioma | Phase 2 | - | - | |
Advanced cancer | Phase 1 | CA | 01 Jan 1999 | |
Advanced Malignant Solid Neoplasm | Phase 1 | CA | 01 Jan 1999 |
Phase 2 | 18 | plkzhgrukc(jqzijjwtxf) = kvbkqwtqnh dzwyjbakhs (hnfimaldjt, 3.75 - 7.49) | Negative | 01 Jul 2006 | |||
Phase 2 | 10 | ahchxkkyhg(fbgowrizet) = SarCNU caused pulmonary toxicity in patients with recurrent malignant glioma omhptttbbw (gqmjqygqee ) | - | 01 Dec 2005 | |||
Phase 1 | - | inzddwscgm(jrnecppcbp) = Anemia occurred but was mild tmyadfqrzc (gsmuicglad ) View more | - | 15 Jan 2003 |