Last update 20 Dec 2024

Efgitasialase alfa

Overview

Basic Info

Drug Type
Antibody fusion proteins
Synonyms
Bi-Sialidase, E 602, E-602
Target
Mechanism
NEU2 modulators(neuraminidase 2 modulators), T lymphocytes stimulants
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced cancerPhase 2
US
11 Feb 2022
Bladder CancerPhase 2
US
11 Feb 2022
Breast CancerPhase 2
US
11 Feb 2022
Colonic CancerPhase 2
US
11 Feb 2022
Gastrooesophageal junction cancerPhase 2
US
11 Feb 2022
Head and Neck NeoplasmsPhase 2
US
11 Feb 2022
MelanomaPhase 2
US
11 Feb 2022
Non-Small Cell Lung CancerPhase 2
US
11 Feb 2022
Ovarian CancerPhase 2
US
11 Feb 2022
Pancreatic CancerPhase 2
US
11 Feb 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
21
E-602 20 mg/kg + cemiplimab 350 mg
gfmqdpumgd(daztndwblk) = tzqwantzuc oedefdyybo (qcdjagcick )
Positive
05 Nov 2024
Phase 1/2
32
fblaauzjmm(oiirnyvbhl) = The most frequent adverse event was infusion-related reactions which were primarily grade 1-2 and clinically manageable. aejkfrdqxa (vygomoraza )
Positive
14 Apr 2023
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Approval

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Regulation

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