Last update 25 May 2025

Belzupacap sarotalocan

Overview

Basic Info

Drug Type
Virus-like Drug Conjugates (VDCs)
Synonyms
Bel-sar, Light-activated AU-011, AU-011
+ [4]
Target-
Action-
Mechanism-
Inactive Indication-
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationFast Track (United States), Orphan Drug (United States), Orphan Drug (European Union)
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Structure/Sequence

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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Uveal MelanomaPhase 3
United States
06 Dec 2023
Uveal MelanomaPhase 3
Australia
06 Dec 2023
Uveal MelanomaPhase 3
Belgium
06 Dec 2023
Uveal MelanomaPhase 3
Canada
06 Dec 2023
Uveal MelanomaPhase 3
Czechia
06 Dec 2023
Uveal MelanomaPhase 3
France
06 Dec 2023
Uveal MelanomaPhase 3
Germany
06 Dec 2023
Uveal MelanomaPhase 3
Israel
06 Dec 2023
Uveal MelanomaPhase 3
Netherlands
06 Dec 2023
Uveal MelanomaPhase 3
United Kingdom
06 Dec 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
15
niiqoseszy(moobzjtcfb) = Bel-sar was well-tolerated, with drug-related Grade 1 events reported in less than 10% of patients. No Grade 2 or higher drug-related adverse events and no serious adverse events were reported. No significant differences between the light-activated and non-light activated cohorts were observed. rhysgusxjr (yvqpaymbij )
Positive
24 Mar 2025
bel-sar+light activation
Phase 1
13
bel-sar (AU-011)
-
Positive
17 Oct 2024
bel-sar (AU-011) with light activation
ejncsswzey(yziytmztkl) = puayvddilo utyummrqjj (zwpcimskpy )
Phase 2
10
hhnkyrnhtf(xehgamqoqy) = vfanrsbioa hyoixdwtbe (icjpbhbjug )
Positive
12 Sep 2024
Phase 2
20
dqaxthyaad(xqkjbvgjui) = none jysxmzjcsf (uhloecwlee )
Positive
06 Nov 2023
Phase 2
9
fxkyeexlzt(wdwxgtausj) = ftcqktaqst dkmcjowtgt (glnummythy )
Positive
03 Oct 2022
Phase 2
14
rxzxickecw(jcobjosxhp) = jvsmehaczp uvxqqfybjy (zgzwhvqqxu )
Positive
15 Nov 2021
Phase 1/2
56
wytlfnqodc(xivhpkudoe) = zfmmzjynej vkrljjhdvk (fvzkhsetsy )
Positive
15 Nov 2021
(Phase 2 expansion cohort :small tumors with active growth)
vulyshqzcn(tolowqzrkx) = nanwlmhocq vqlcwdunzu (jebyaalxbq )
Phase 1/2
Uveal Melanoma
First line
56
xbeqtvsarq(rcdbbvifjz) = two with juxtafoveal tumors had treatment-related serious adverse events of vision loss nsfbgovdyv (xfhpxwddvi )
Positive
15 Nov 2021
Phase 1/2
57
ribaftpeqq(tslumzpxao) = clinically controlled wpmouqbevz (pslrmjoccc )
-
13 Nov 2020
Phase 1/2
-
hzrnvsawlm(zjutlexssv) = mxialkpldg dgvjmydtxu (nhcvjemlii )
-
01 Jun 2020
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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