Drug Type Small molecule drug |
Synonyms (+/-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone, Halofuginone, Halofuginone hydrobromide (USAN) + [6] |
Target |
Mechanism Collagen inhibitors, Angiogenesis inhibitors |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
RegulationOrphan Drug (US) |
Molecular FormulaC16H18Br2ClN3O3 |
InChIKeySJUWEPZBTXEUMU-AJYMSAGVSA-N |
CAS Registry64924-67-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D04413 | Halofuginone Hydrobromide | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Muscular Dystrophy, Duchenne | Phase 2 | US | 01 Oct 2013 | |
Bladder Cancer | Phase 2 | IL | - | |
Bladder Cancer | Phase 2 | GB | - | |
Neoplasms | Phase 2 | BE | - | - |
Neoplasms | Phase 2 | - | - | |
Neoplasms | Phase 2 | NL | - | - |
Scleroderma, Systemic | Phase 2 | GB | - | |
Coronary Restenosis | Preclinical | US | - | - |
Liver Cirrhosis | Preclinical | IL | - | |
Renal fibrosis | Preclinical | IL | - |
Not Applicable | - | - | kuiwzcrghe(wjaxprwfhf) = bhhyyhejka lnuxisrylr (zroyqahidv ) View more | - | 01 May 2022 | ||
PBS | kuiwzcrghe(wjaxprwfhf) = vwxhavydkv lnuxisrylr (zroyqahidv ) View more |