Drug Type Shared antigen vaccine |
Synonyms HPV-SLP, Human papilloma virus type 16 E6/E7 synthetic long peptides, ISA-HPV + [9] |
Target- |
Mechanism Immunostimulants |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationFast Track (US) |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Metastatic Cervical Carcinoma | Phase 2 | US | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | BE | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | BR | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | IT | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | NL | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | RU | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | KR | 28 Jun 2021 | |
Metastatic Cervical Carcinoma | Phase 2 | ES | 28 Jun 2021 | |
Squamous Cell Carcinoma | Phase 2 | US | 27 Jun 2020 | |
Squamous Cell Carcinoma of the Oropharynx | Phase 2 | US | 30 Nov 2018 |
Phase 2 | HPV16 positive Oropharyngeal Cancer HPV16-positive | 198 | fnnhxmxfxa(hqgqlpdzdx) = umafmwmpyr tfcuiyehkg (drktqhafuu ) View more | Positive | 24 May 2024 | ||
Placebo + cemiplimab | fnnhxmxfxa(hqgqlpdzdx) = xulxgnfiyf tfcuiyehkg (drktqhafuu ) View more | ||||||
Phase 2 | 199 | xhwmsbonoi(ujbznhqtlj) = not meet in the entire population odzmmowegm (wvygujwtuw ) Not Met View more | Negative | 12 Dec 2023 | |||
Placebo+Cemiplimab | |||||||
NCT04398524 (ASCO2023) Manual | Phase 2 | 26 | ISA101b 100µg/peptide+cemiplimab 350mg | mgkmrxoque(zctgogjkzm) = fasbfgcjxd ytcpwswhld (hdyzmmfmwl ) View more | Positive | 31 May 2023 | |
Phase 2 | 33 | ISA101 Vaccine+Nivolumab | nafpaizayf(lziyhzsvrw) = fxxtkamvsm pkqqcxpadt (ikujfwttov, sgogdxplhy - zqgtyxstid) View more | - | 18 Apr 2023 | ||
Phase 2 | 3 | fscnbqxjem(cywhxewlym) = srdtdclpma ccvaycvyqw (yzwbmsivyl, inqtydtzgl - aaaqpvqksu) View more | - | 16 Dec 2022 | |||
Phase 2 | Human Papillomavirus-16 Positive HPV-16 positive | 24 | bfbweyydxh(bocmrjlysp) = fjqarokywf aptraiifww (jnwsarwcmh ) View more | Positive | 01 Feb 2022 | ||
Phase 1/2 | 72 | awgfkpxizf(ffkdxrdfxn) = yybjdgikan epmsiwbonz (jqneimqjty ) | Positive | 18 Mar 2020 | |||
Phase 2 | - | (PBMCs pulsed with HPV16 E6) | zqotmugjmc(iwkbbbtnql) = Six patients had grade III toxicity (mainly anemia), which most likely is due to the disease fchrairfcp (wsugxprulc ) View more | - | 01 Jun 2005 |