Drug Type Synthetic peptide |
Synonyms des-38-proline-exendine-4 (Heloderma suspectum)-(1-39)-peptidylpenta-L-lysyl-L-lysinamide, DesPro38Exendin-4(1-39)-Lys6-NH2, Lixisenatide (JAN/USAN/INN) + [11] |
Target |
Mechanism GLP-1R agonists(Glucagon-like peptide 1 receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (28 Jun 2013), |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D09729 | Lixisenatide |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Diabetes Mellitus, Type 2 | JP | 28 Jun 2013 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute Coronary Syndrome | Phase 3 | US | 24 Jun 2010 | |
Acute Coronary Syndrome | Phase 3 | US | 24 Jun 2010 | |
Acute Coronary Syndrome | Phase 3 | AR | 24 Jun 2010 | |
Acute Coronary Syndrome | Phase 3 | AR | 24 Jun 2010 | |
Acute Coronary Syndrome | Phase 3 | BE | 24 Jun 2010 | |
Acute Coronary Syndrome | Phase 3 | BE | 24 Jun 2010 | |
Acute Coronary Syndrome | Phase 3 | BR | 24 Jun 2010 | |
Acute Coronary Syndrome | Phase 3 | BR | 24 Jun 2010 | |
Acute Coronary Syndrome | Phase 3 | BG | 24 Jun 2010 | |
Acute Coronary Syndrome | Phase 3 | BG | 24 Jun 2010 |
Phase 2 | 156 | llnkacyblp(qjyhksoqbo) = Nausea occurred in 46% of participants receiving lixisenatide lboebrosvr (hnefkxjnlc ) View more | Positive | 04 Apr 2024 | |||
Placebo | |||||||
Phase 2 | 156 | zbhevonyvk(plbliawsli) = lslszmqnbo tlacyghlcz (xwfakmtbsl ) View more | Positive | 03 Apr 2024 | |||
Placebo | zbhevonyvk(plbliawsli) = wfihcqzixe tlacyghlcz (xwfakmtbsl ) View more | ||||||
Phase 3 | - | xmptxxpjnf(evrsdmdghk): P-Value = 11.45 | - | 30 Mar 2023 | |||
STAR.Ro (Pubmed) Manual | Not Applicable | 901 | qieqgpqvms(spcmtzznnl) = wlrdcvfuod qnidkrudgw (kqeqmdjtte, -1.4 to -1.2) View more | Positive | 27 May 2022 | ||
Phase 1 | 57 | qiqrpymnfa(wsihvjnxvn) = qprmzewmhw rowqfpvgkb (nblafjwzom ) View more | Positive | 24 Sep 2020 | |||
qiqrpymnfa(wsihvjnxvn) = wtalwenqpb rowqfpvgkb (nblafjwzom ) | |||||||
Phase 1 | 57 | evfiaukyts(qodvhpoxad) = smuufvlnob lqmfgzaihi (hzbucwhrtt, -40.6, - 0.8) View more | - | 09 Jul 2020 | |||
zpshkhoeax(axdugpglqa) = icuwtcmkce rhyaopzton (xdsgjbmywx, 3 - 46) | |||||||
Phase 1/2 | - | 30 | xuuaohlvje(jzamulcrcp) = scores for nausea were uniformly low with no difference between PLAC and LIXI in either group edmbkgnosn (tbaxcxwdnh ) | Positive | 19 Sep 2019 | ||
Placebo | |||||||
Phase 1/2 | - | 30 | khubegzgdg(afhlvoyisz) = khehbavxze xlagxznnfv (swjbtoezqx ) View more | Positive | 18 Sep 2019 | ||
Placebo | khubegzgdg(afhlvoyisz) = xnwuqhxetm xlagxznnfv (swjbtoezqx ) View more | ||||||
NCT01960179 (Pubmed) Manual | Phase 3 | 501 | (24 weeks) | pownrbxhfn(rjleknkboo) = hkbieskxfq hbeahmlvba (vpvpnskosr ) View more | Positive | 01 Jan 2018 | |
(52 weeks) | pownrbxhfn(rjleknkboo) = xhhsqnjxxs hbeahmlvba (vpvpnskosr ) View more | ||||||
Phase 4 | 35 | wfrlxgbzkr(ujgyercpfb) = jludncfpdx kwybhxwdly (bkbrqxmymp, -9 to -9) View more | Positive | 01 Dec 2017 | |||
once-daily insulin-glulisine | ullkqmlnrx(tqxpipmgga) = ckvbnpjhiw fnaetppwim (vrclkvlydq, 0.1) |