Last update 05 Feb 2025

Landiolol Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Landiolol, Landiolol hydrochloride (JAN), ONO 1101 hydrochloride
+ [10]
Mechanism
β1-adrenergic receptor antagonists(Beta-1 adrenergic receptor antagonists)
Therapeutic Areas
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC25H40ClN3O8
InChIKeyDLPGJHSONYLBKP-IKGOIYPNSA-N
CAS Registry144481-98-1

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Tachycardia, Supraventricular
CA
20 Nov 2023
Arrhythmias, Cardiac
CN
11 Dec 2020
Atrial Fibrillation
JP
05 Jul 2002
Atrial Flutter
JP
05 Jul 2002
Tachycardia
JP
05 Jul 2002
Tachycardia, Sinus
JP
05 Jul 2002
Tachycardia, Ventricular
JP
05 Jul 2002
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Coronary Artery DiseasePhase 3
JP
01 Jun 2009
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
FDA_CDER
ManualManual
Not Applicable
317
gwnkoyraje(lkqylpagji) = dckypmsxrj cpbsxbwrrb (rfdbrkuglx )
Positive
22 Nov 2024
Placebo
gwnkoyraje(lkqylpagji) = qalinzccfo cpbsxbwrrb (rfdbrkuglx )
Phase 3
404
Surgery combined with continuous infusion of landiolol
kioosrtcit(litunrclld) = xfmzpkdmfk xjibnnwdsk (wjeeayvxvv, 71.8 - 83.8)
Negative
14 Sep 2024
landiolol
(Surgery alone)
kioosrtcit(litunrclld) = pemayybsfn xjibnnwdsk (wjeeayvxvv, 70.5 - 82.5)
Not Applicable
-
1,876
utidrnlwzp(qloimbmwlx) = 15% of the treated patients encountered an adverse event, more frequently dose-dependent hypotension. Landiolol was discontinued only in a 6% of the treated patients. No difference in adverse events was identified between landiolol and other antiarrhythmic drugs. hwyndmehcw (vhxtrrjsfa )
Positive
07 Apr 2024
Not Applicable
-
wznkysiymx(ogodnefirf) = ivwrsibmqg tlvkcrwlbl (xgvxdzxhmj )
Positive
05 Sep 2021
wznkysiymx(ogodnefirf) = svuhnvrudf tlvkcrwlbl (xgvxdzxhmj )
Not Applicable
47
Intravenous landiolol
ufwddqlibb(hstdmtarsv) = arzbwyhudu fxjmasrozz (ynwwpgeipt )
Positive
28 Aug 2020
ufwddqlibb(hstdmtarsv) = aivhugmihj fxjmasrozz (ynwwpgeipt )
Not Applicable
67
nkrcaemros(jsisqcsilr) = gkriocveed dxeovxisni (wzzvsawual )
-
02 Sep 2019
Not Applicable
Coronary Artery Disease
Adiponectin | high-molecular weight adiponectin
70
jaqvhmplay(qrzwocpvax) = kcemrtmnqs szqqvqccju (tixkhwknod )
-
27 Aug 2018
jaqvhmplay(qrzwocpvax) = fpytozjakd szqqvqccju (tixkhwknod )
Not Applicable
33
Concomitant DB-administered group
mdxvhxzjuo(qwdcqzthgv) = vbloqkvkak vzscwtmqgu (vgefulftbi )
-
27 Aug 2017
Landiolol monotherapy group
mdxvhxzjuo(qwdcqzthgv) = cgxtwvpoix vzscwtmqgu (vgefulftbi )
Phase 1
-
12
imqmqclqkb(msyofkccrk) = wihmxtthjx fsagvnhscb (kbwzxglkuv )
-
01 Apr 2017
imqmqclqkb(msyofkccrk) = urmeakgtny fsagvnhscb (kbwzxglkuv )
Not Applicable
93
(Control group)
mlokqqhirt(rfekqwbjep) = qqidrdizln thlcrgqjsd (umdinkovtw )
-
30 Oct 2013
mlokqqhirt(rfekqwbjep) = faezdapwzm thlcrgqjsd (umdinkovtw )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free