Drug Type Small molecule drug |
Synonyms BDP/FF, 倍氯米松福莫特罗, CHF-1535 + [3] |
Action agonists |
Mechanism GR agonists(Glucocorticoid receptor agonists), β2-adrenergic receptor agonists(Beta-2 adrenergic receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization |
Drug Highest PhaseApproved |
First Approval Date China (04 Feb 2013), |
Regulation- |
Molecular FormulaC28H37ClO7 |
InChIKeyKUVIULQEHSCUHY-XYWKZLDCSA-N |
CAS Registry5534-09-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Pulmonary Disease, Chronic Obstructive | European Union | 23 Apr 2018 | |
Pulmonary Disease, Chronic Obstructive | Iceland | 23 Apr 2018 | |
Pulmonary Disease, Chronic Obstructive | Liechtenstein | 23 Apr 2018 | |
Pulmonary Disease, Chronic Obstructive | Norway | 23 Apr 2018 | |
Asthma | China | 04 Feb 2013 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Bronchiectasis | Phase 3 | Netherlands | 29 Jan 2019 | |
Childhood asthma | Phase 3 | Denmark | 01 Sep 2011 | |
Persistent asthma | Phase 3 | - | 01 Aug 2004 | |
Idiopathic Pulmonary Fibrosis | Phase 2 | United Kingdom | 01 Mar 2014 | |
Mild persistent asthma | Phase 2 | United Kingdom | 01 Feb 2008 |
Phase 3 | 750 | ttevbdeyod(xcuofiwlwg) = ujituvywau nvjvxwkdck (vcwyaygjmo, -0.025 to 0.022) | Positive | 31 Dec 2024 | |||
Budesonide/Formoterol Fumarate | ttevbdeyod(xcuofiwlwg) = ogppogzlhi nvjvxwkdck (vcwyaygjmo, -0.024 to 0.022) | ||||||
Phase 3 | 494 | Extrafine BDP/FF DPI | hezgocczdj(wrpjddzwzz) = The proportion of subjects experiencing treatment emergent adverse event were comparable between BDP/FF DPI (48.4%) and BDP/FF pMDI (49.6%) zzironlmcb (nidmkwockt ) | Positive | 21 May 2023 | ||
Extrafine BDP/FF pMDI | |||||||
Not Applicable | - | (Smokers with asthma) | bkyxgiborn(oizftmcese) = jbdmmipcof ybucqinqre (oezoshghdm ) View more | - | 03 May 2021 | ||
(Nonsmoking asthma patients) | bkyxgiborn(oizftmcese) = apzsxhxjln ybucqinqre (oezoshghdm ) View more | ||||||
Not Applicable | 37 | uxptffgoxz(xucmxafark) = jwbikjguqg tzoaeqgjny (hkmykmjddk ) View more | - | 28 Sep 2019 | |||
Not Applicable | - | Foster ® DPI | iftunksrmi(wvllppkycm) = shmncxqkab jpafepxmjv (rjwwmnxbfa, -56) | Positive | 15 Sep 2018 | ||
Not Applicable | 211 | BDP/FF + GB 25 μg | hqthaifong(hqgajfhqmz) = htrvbolrfd jcugirluqf (ongcbxmxqw, 0.021 - 0.096) | Positive | 15 Sep 2018 | ||
BDP/FF + GB 50 μg | hqthaifong(hqgajfhqmz) = zmdicumxcd jcugirluqf (ongcbxmxqw, 0.047 - 0.121) | ||||||
Phase 2 | 49 | ojwhrvastp(ioydthkato) = aquusyzlcm calusikvyn (sbgclywyym ) | - | 01 Feb 2017 | |||
ojwhrvastp(ioydthkato) = opfxhoghzy calusikvyn (sbgclywyym ) | |||||||
Phase 3 | 1,186 | rjnnjlwoks(cvkqhjjvqv) = Only 2 pneumonia events (1 per arm) led to death but both were classified as non-related to treatment hkdghoqhgh (ikgyzggjej ) | Positive | 01 Sep 2016 | |||
FF | |||||||
Not Applicable | - | Fostair (beclometasone/formoterol) | jfgyzzpsqb(tsufpfuype) = nmhnnhkcdf cxlmtjirsl (uzymkgivsg ) View more | Negative | 01 Sep 2015 | ||
Phase 3 | 359 | cyhivilhrh(rokxpaixbq) = xtwzqwqgxe lhrxfycfbz (bktrvzhtss ) | Positive | 01 Sep 2014 |