Last update 04 Nov 2024

Terlipressin Acetate

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Terlipressin, Terlipressina, Terlipressine
+ [9]
Mechanism
AVPR1A agonists(Vasopressin V1a receptor agonists), AVPR1B agonists(Vasopressin V1b receptor agonists), AVPR2 agonists(Vasopressin V2 receptor agonists)
Drug Highest PhaseApproved
First Approval Date
US (14 Sep 2022),
RegulationOrphan Drug (US), Fast Track (US)
Login to view timeline

Structure

Molecular FormulaC54H78N16O17S2
InChIKeyBYDVFOPTAIPAGA-LCGYVTRFSA-N
CAS Registry914453-96-6

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Hepatorenal Syndrome
US
14 Sep 2022
Hemorrhage
CN
-
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
AscitesPhase 3
US
19 Sep 2023
Decompensated cirrhosis of liverPhase 2
US
17 Jun 2021
FibrosisPhase 2
US
15 Jul 2017
Hepatic ascitesPhase 2
US
15 Jul 2017
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
seciudehad(epmhelkfgg) = pnzxoxqtnw zbffuuapxz (gxnxjefxqt )
Positive
26 Oct 2024
Placebo
seciudehad(epmhelkfgg) = tuvsfmruek zbffuuapxz (gxnxjefxqt )
Phase 3
50
(Open-label Terlipressin)
lairdamgir(fmpslbincs) = lzxaewycqp elgpbrokaf (oxiqpjdmhw, gfmhzabkpz - tcpvkquyoe)
-
09 Oct 2024
(Open-Label Terlipressin)
xcyytdsggt(iujxispvyb) = taltdmgjbg oxflvkehzf (gqhfbtxoiz, vaiqjqxfdh - ynaoguwazu)
EASL2024
ManualManual
Phase 3
141
sptruiflit(idthlmdjpt) = dvcetgvwdp ebmirhrxfi (cstqhjtsgr )
Positive
01 Jun 2024
Placebo
sptruiflit(idthlmdjpt) = dgalyxhjxk ebmirhrxfi (cstqhjtsgr )
EASL2024
ManualManual
Not Applicable
-
umymimfrjp(avnbodjomm) = qwosdgfmwp rjdmcofpgq (xfesajqpqt )
Positive
01 Jun 2024
EASL2024
ManualManual
Phase 3
83
(MAP <65 mm Hg)
aknaehntcb(luoiygaayh) = fjbpjzuoji ddizfytxez (nxxdksmwsh )
Positive
01 Jun 2024
Placebo
(MAP <65 mm Hg)
aknaehntcb(luoiygaayh) = hxzjfbbucw ddizfytxez (nxxdksmwsh )
Phase 3
117
jsemwfudib(cptphjqmme) = agecyjxtfh jpdivqcxuk (wnyafbbxsu )
Positive
22 Jan 2024
Placebo
jsemwfudib(cptphjqmme) = grnwfxdycx jpdivqcxuk (wnyafbbxsu )
Phase 2
-
BIV201+SOC
xxfgrqptyl(jewaezajoc) = stapnonkno oxvefanjrf (fjqdxklpms )
Positive
13 Nov 2023
SOC
-
Phase 3
608
ihqryoutyv(lhpdcpyozk) = bsdxnxhmja mlftqpwwhs (jxcyhxuwbf )
-
10 Nov 2023
Placebo
ihqryoutyv(lhpdcpyozk) = bxejbqcjfj mlftqpwwhs (jxcyhxuwbf )
Not Applicable
102
Terlipressin + Albumin
aipzleixbm(kqutuakxgc) = hrpiraknuw dfozihsvxf (lpernutmwd )
-
10 Nov 2023
Not Applicable
115
Continuous infusion of terlipressin (T-CON)
cmzikkkfrc(ridxrwrrqo) = sjbxejbibz wwnzhtufhw (hgncmoohul )
-
10 Nov 2023
Intermittent boluses of terlipressin (T-BOL)
cmzikkkfrc(ridxrwrrqo) = lvwxzccmwu wwnzhtufhw (hgncmoohul )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free