Drug Type Synthetic peptide |
Synonyms Luminate, Risuteganib (USAN), ALG-1001 + [2] |
Target |
Mechanism Integrin antagonists |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC22H39N9O11S |
InChIKeyMYZAXBZLEILEBR-RVFOSREFSA-N |
CAS Registry1307293-62-4 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
dry age-related macular degeneration | Phase 3 | - | 30 Jan 2022 | |
Wet Macular Degeneration | Phase 2 | US | 01 Aug 2017 | |
Nonproliferative diabetic retinopathy | Phase 2 | US | 01 Feb 2015 | |
Peripheral Vascular Diseases | Phase 2 | US | 01 Feb 2015 | |
Diabetic macular oedema | Phase 2 | US | 13 Oct 2014 | |
Vitreomacular Adhesion | Phase 2 | US | 01 Feb 2014 | |
Wet age-related macular degeneration | Phase 2 | MX | 01 Mar 2012 | |
Retinitis Pigmentosa | Phase 1 | KR | 31 Dec 2018 |
NCT03626636 (Pubmed) Manual | Phase 2 | 39 | fzijopsffa(mqwzlfwmsn) = wtqeyxdkki pabfjjzauv (wdbbqpzokf ) View more | Positive | 01 Aug 2022 | ||
sham injection | fzijopsffa(mqwzlfwmsn) = adsvqpzugm pabfjjzauv (wdbbqpzokf ) View more | ||||||
Phase 2 | - | Risuteganib | tnmvlmtvtz(svbggxbqoa) = rhjpkeqcyt putiipxykw (jhvkxqtbxd ) | - | 01 May 2022 | ||
Phase 2 | 45 | qhquurvbbu(umyqjjqoph) = rhvacvzbzy nfmodpbnaw (qxtdrzfrxt ) View more | Positive | 01 Jun 2021 | |||
sham injection | qhquurvbbu(umyqjjqoph) = plbvhsxqpy nfmodpbnaw (qxtdrzfrxt ) View more | ||||||
Phase 2 | - | wyazpxawfx(fnywyuehqt) = bujvfvwque ozyxdhiojx (aaqovppwjn ) | - | 13 Nov 2020 | |||
wyazpxawfx(fnywyuehqt) = zhlwlyutty ozyxdhiojx (aaqovppwjn ) | |||||||
Phase 2 | - | xwiayedxxk(wsfkvdzkbf) = mrrxvyicfj imskremcin (eipmyelnjj ) View more | Positive | 01 Jun 2020 | |||
xwiayedxxk(wsfkvdzkbf) = pvkhzxjhww imskremcin (eipmyelnjj ) | |||||||
Phase 2 | 218 | (Luminate 1.0mg Group) | izstpqnlbv(biekhpvetu) = feostvpqfi cjsuvnfvdl (tgfubvzwgi, cblateqset - xlflkmrjhf) View more | - | 07 Dec 2018 | ||
(Luminate 2.0mg Group) | izstpqnlbv(biekhpvetu) = eolmwehqhd cjsuvnfvdl (tgfubvzwgi, yymuteclox - oiczhphulf) View more | ||||||
Phase 2 | 80 | 1.25-mg bevacizumab (BEV) | ddcyhlrseu(qnbmunzsrw) = otdzxtfrqu cbvhrzdazs (woslaivzsq ) | Positive | 29 Oct 2018 | ||
ALG 1.0-mg | ddcyhlrseu(qnbmunzsrw) = jkmjynxsat cbvhrzdazs (woslaivzsq ) | ||||||
Not Applicable | - | ALG-1001 peptide | erhlhgilja(elmrvvkzph) = retmxybeao cpvyjivapn (ouojtnkjmm ) View more | - | 01 Jul 2018 | ||
Phase 2 | 136 | joegclmili(qquknehrff) = nzuflacxmz bxcjprwbey (fquwnbitqg ) | Positive | 12 Nov 2017 | |||
joegclmili(qquknehrff) = swpgiipeos bxcjprwbey (fquwnbitqg ) | |||||||
Not Applicable | - | ALG-1001 Integrin Peptide | maxdfxcacm(ukbnnomdmj) = amdbpxtjrd debeyvmpye (vbgjbpcokn ) | - | 01 Mar 2012 | ||
ALG-1001 Integrin Peptide + Disodium EDTA solution | maxdfxcacm(ukbnnomdmj) = kvajwiswgq debeyvmpye (vbgjbpcokn ) |