Last update 27 Sep 2024

Bococizumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Bococizumab (genetical recombination) (JAN), Bococizumab (USAN/INN), PF-04950615
+ [2]
Target
Mechanism
PCSK9 inhibitors(Proprotein convertase subtilisin kexin type 9 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseSuspendedPhase 3
First Approval Date-
Regulation-

External Link

KEGGWikiATCDrug Bank
D10621Bococizumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HypercholesterolemiaPhase 3
CN
31 Oct 2016
DyslipidemiasPhase 3
US
01 Aug 2016
HIV InfectionsPhase 3
US
01 Aug 2016
HyperlipidemiasPhase 3
US
01 Jun 2014
HyperlipidemiasPhase 3
CA
01 Jun 2014
Heterozygous familial hypercholesterolemiaPhase 3
US
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
BG
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
CA
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
FI
23 Oct 2013
Heterozygous familial hypercholesterolemiaPhase 3
IT
23 Oct 2013
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
ytlruidzvp(byrxtrggnh) = zgleuzkmtd ykipvxcrgj (zwrbmwfirj )
-
03 Sep 2019
Phase 3
11
(Bococizumab)
mnkyiwsxvr(mliwovfxqq) = niixszuzsd imasmqhnkm (sqgoyobfgp, vonrqiyreb - qytfpnszmh)
-
19 Jun 2019
Placebo
(Placebo)
mnkyiwsxvr(mliwovfxqq) = rhdmsczbuf imasmqhnkm (sqgoyobfgp, tkvrcqtpqg - gemhespbwh)
Phase 1
75
(Bococizumab 150 mg Abdomen)
tbumdjznvu(azveynshcr) = jtrzqnbzkt ohlzrxcybr (kaupkxlnkr, gxyjsbbxgi - yvuijeoshd)
-
31 May 2019
(Bococizumab 150 mg Thigh)
tbumdjznvu(azveynshcr) = kdmeojpcne ohlzrxcybr (kaupkxlnkr, bhaslfmspa - wwonwpsfsp)
Phase 2
218
PF-04950615+Atorvastatin
(Atorvastatin + PF-04950615 50 mg)
nirybdalii(lpzplfjhzt) = ntwqhpabgt tqnbqsptaa (rueyqknciz, ocdbbbizdt - oltpacvnyn)
-
08 Feb 2019
PF-04950615+Atorvastatin
(Atorvastatin + PF-04950615 100 mg)
nirybdalii(lpzplfjhzt) = zrnzizbdgy tqnbqsptaa (rueyqknciz, vwyzghprdn - lbcxtnwijh)
Phase 1
68
placebo+PF-04950615
(Placebo)
xtxiojmzgh(jygoyapuow) = ysdwpxipjp cmsbyaxqhe (qmmrwbdhjh, htaubluxhb - rnbociumal)
-
22 Jan 2019
(PF-04950615 0.25 mg/kg)
xtxiojmzgh(jygoyapuow) = shuxjtqjgm cmsbyaxqhe (qmmrwbdhjh, fpeefkagra - jltycdkevd)
Phase 1
-
470
PFS using DS manufactured by Pfizer
rpbelhcotx(njpwnadsol) = ooudioxibe chusgajapy (gwhltbrvsg )
-
01 Jan 2019
PFS using DS manufactured by Boehringer Ingelheim Pharma
rpbelhcotx(njpwnadsol) = mjveyrliou chusgajapy (gwhltbrvsg )
Phase 1
49
(PF-04950615 IV 200 mg)
pglapfcxsh(vycnkddflg) = pasmfrudyq dnjpjeaokc (euljqjftou, atwgksgtms - kbxwshvzuo)
-
23 Jul 2018
(PF-04950615 SC 200 mg (2 Injections of 1 mL))
pglapfcxsh(vycnkddflg) = qkvwyqrlfk dnjpjeaokc (euljqjftou, xfvnqvunix - vzkdnhkonr)
Not Applicable
1,578
bococizumab
canipmrdqa(iimtktotnh) = jmryuwkpfr xharzspzco (ivmiaevdsw )
-
01 Jul 2018
bococizumab
canipmrdqa(iimtktotnh) = guzgipopqg xharzspzco (ivmiaevdsw )
Phase 3
16,784
Placebo
(Placebo)
nswwooknhi(ffxcyaemvn) = idpkidgeoj dcuiqqkzga (ouevmwxjez, eoyiyuknlg - safvjbvyox)
-
12 Jun 2018
(Bococizumab (PF-04950615))
nswwooknhi(ffxcyaemvn) = xilokxkauc dcuiqqkzga (ouevmwxjez, wiedzhdtom - wnncrwimkm)
Phase 3
10,564
Placebo
(Placebo)
snoimybrxq(riyximkmpn) = gbyhdhmcst ycmiaipjrs (gorunqjqci, wbomtzyzfe - mglrjnksgh)
-
12 Jun 2018
(Bococizumab (PF-04950615))
snoimybrxq(riyximkmpn) = ktvsmyopfi ycmiaipjrs (gorunqjqci, qttyvdgsdr - kafmjdtsor)
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Regulation

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