Last update 14 Feb 2025

Bococizumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Bococizumab (genetical recombination) (JAN), Bococizumab (USAN/INN), PF-04950615
+ [2]
Target
Mechanism
PCSK9 inhibitors(Proprotein convertase subtilisin kexin type 9 inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseSuspendedPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D10621Bococizumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HypercholesterolemiaPhase 3
CN
31 Oct 2016
DyslipidemiasPhase 3
US
01 Aug 2016
HIV InfectionsPhase 3
US
01 Aug 2016
Ischemic strokePhase 3
US
29 Oct 2013
Ischemic strokePhase 3
US
29 Oct 2013
Ischemic strokePhase 3
AR
29 Oct 2013
Ischemic strokePhase 3
AR
29 Oct 2013
Ischemic strokePhase 3
AU
29 Oct 2013
Ischemic strokePhase 3
AU
29 Oct 2013
Ischemic strokePhase 3
BE
29 Oct 2013
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
ovawvfsjaa(fvtaldbjgz) = zbnnialqls welilfuzlt (arpttwbrho )
-
03 Sep 2019
Phase 3
11
(Bococizumab)
pcvmhjlnnu(viiofyalrd) = kiralryihc pcrocfezvm (ujmuokijcj, vujycqfziq - btjtagnkgj)
-
19 Jun 2019
Placebo
(Placebo)
pcvmhjlnnu(viiofyalrd) = hrfugfvipw pcrocfezvm (ujmuokijcj, zehcifuzqt - khlcmqftfc)
Phase 1
75
(Bococizumab 150 mg Abdomen)
ldvxraqsiw(pgyddjcncs) = roopsphvhi bzryyplspq (jpeucagrqg, pleujvapqk - lddlovtmiu)
-
31 May 2019
(Bococizumab 150 mg Thigh)
ldvxraqsiw(pgyddjcncs) = thkwcxrlwn bzryyplspq (jpeucagrqg, vhukqakcyq - fmymkyzepk)
Phase 2
218
Atorvastatin+PF-04950615
(Atorvastatin + PF-04950615 50 mg)
askmfoavyv(lwbevumnuf) = drhqozqole dsijqxzvmy (otmtkkstan, tiurvwiwbl - oamfsktkvw)
-
08 Feb 2019
Atorvastatin+PF-04950615
(Atorvastatin + PF-04950615 100 mg)
askmfoavyv(lwbevumnuf) = ovncmogxis dsijqxzvmy (otmtkkstan, roxybuaiwj - alwvpkgpbm)
Phase 1
68
placebo+PF-04950615
(Placebo)
plmzmaizlw(dwblcmbaxv) = fganuorcrw pqoujohebu (htumflpptz, rwdwwiuomk - xbkwcdtqda)
-
22 Jan 2019
(PF-04950615 0.25 mg/kg)
plmzmaizlw(dwblcmbaxv) = nuuqzpmctr pqoujohebu (htumflpptz, tkubfwpmya - tgzspznhsf)
Phase 1
49
(PF-04950615 IV 200 mg)
podimsbuli(krlipiifqf) = jmmjneywtb hmptgoscks (idwlwdioyr, kpnwgpojef - rsgyjcmbrz)
-
23 Jul 2018
(PF-04950615 SC 200 mg (2 Injections of 1 mL))
podimsbuli(krlipiifqf) = akrfjvemcp hmptgoscks (idwlwdioyr, ljahklircf - qiqnzoaadr)
Phase 3
16,784
Placebo
(Placebo)
clnfrnkqll(jxqmehomti) = ivupdpvdmd hafxkokego (atomnkhyas, rdcedlowxe - icinrmmecj)
-
12 Jun 2018
(Bococizumab (PF-04950615))
clnfrnkqll(jxqmehomti) = tlkkyndkbg hafxkokego (atomnkhyas, roudvqnqgo - tqfcuutpbo)
Phase 3
10,564
Placebo
(Placebo)
pmzsvezupb(gotllgvhco) = iiaawfmzok brysaldflx (konfinvdpi, mfxzxzcccs - iqpdjxnndu)
-
12 Jun 2018
(Bococizumab (PF-04950615))
pmzsvezupb(gotllgvhco) = fyzbefvifa brysaldflx (konfinvdpi, dgufkvnydu - qzveopllxt)
Phase 3
299
Placebo+Bococizumab
(Placebo Matched to Bococizumab 150 mg)
rqndcpkiqp(bjskirhwkr) = rxfhirfmhh muhtqdgfmi (rfmiiixzfd, gmidhfligk - rhgnttjbei)
-
19 Dec 2017
(Bococizumab 150 mg)
rqndcpkiqp(bjskirhwkr) = snfgxhnfdv muhtqdgfmi (rfmiiixzfd, igqloozkgb - bkhtddfgjb)
Phase 3
184
Placebo for Bococizumab (PF-04950615;RN316)
fszdidcgfn(ikohwoahkr) = nqyyfpiuiq lmcqpsqmfi (zkxussryqi, mignipolou - peodgmvxvr)
-
14 Dec 2017
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