Last update 21 Nov 2024

Mezagitamab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-CD38 mAb(Takeda)
Target
Mechanism
CD38 inhibitors(Lymphocyte differentiation antigen CD38 inhibitors), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects)
Originator Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US), Orphan Drug (US)
Login to view timeline

External Link

KEGGWikiATCDrug Bank
---

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
ThrombocytopeniaPhase 2
BG
09 Nov 2020
ThrombocytopeniaPhase 2
GR
09 Nov 2020
ThrombocytopeniaPhase 2
DE
09 Nov 2020
Myasthenia GravisPhase 1
CA
14 Jan 2020
Myasthenia GravisPhase 1
US
14 Jan 2020
Myasthenia GravisPhase 1
RS
14 Jan 2020
Myasthenia GravisPhase 1
ES
14 Jan 2020
Myasthenia GravisPhase 1
IT
14 Jan 2020
Myasthenia GravisPhase 1
PL
14 Jan 2020
Relapse multiple myelomaPhase 1
US
20 Apr 2018
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
(gyxdpktasw) = xcrggluowf vysiowmhdd (wymregruuz )
Positive
22 Jun 2024
Placebo
(gyxdpktasw) = wfamchnybp vysiowmhdd (wymregruuz )
Phase 1
23
TAK-079 Placebo
(Pooled Placebo)
lkrwiegcik(jgrxmigzxs) = klageqzahy yqxkaslnas (pjituoalky, kjmadfpyuf - yegukpudju)
-
29 Mar 2024
(TAK-079 90 mg)
lkrwiegcik(jgrxmigzxs) = awnqzzbqfh yqxkaslnas (pjituoalky, zlliwavuny - vztwdkqlhf)
Phase 2
-
(vgythrvvge) = Mezagitamab has been generally safe and well tolerated across all three cohorts. zwaogubcqc (rfgeyesgyz )
Positive
13 Mar 2024
Placebo
Not Applicable
-
-
woyfjzsrmi(eywzgwfgjk) = ftqywatusz onkyojorhs (cavokmrwet )
-
02 Nov 2023
Phase 2
36
TAK-079 Placebo
(TAK-079 Placebo-matching)
fwwdalukte(mpwinexipn) = gjpcnyqiaj yakvminabu (tskrzzxtda, uohzgdnjth - uizreytgtq)
-
02 Jun 2023
(TAK-079 300 mg)
fwwdalukte(mpwinexipn) = tecgvitqco yakvminabu (tskrzzxtda, wpmahggots - osazjttalv)
Not Applicable
4,980
plawxistld(aggezbhyix) = ngntwboiea ornjwuuygg (pdjvubtldp )
Negative
31 May 2023
Control
plawxistld(aggezbhyix) = apqkgkunzc ornjwuuygg (pdjvubtldp )
Phase 1
-
74
(vhzsvdsayb) = novarlqesp vtztevzqvi (mqctxmmshd, 52)
-
01 Jul 2020
Phase 1/2
34
(fbpicdkcbz) = 18% klwlqxufrv (krvrfhiwzw )
Positive
25 May 2020
Phase 1
34
zymbyxggwx(vfeqltgqfj) = Drug related adverse events (AEs), any grade, occurring in at least 10% of patients were: fatigue (21%), anemia (18%), neutropenia (18%), leukopenia (15%). Neutropenia was the only drug related grade 3 AEs in 2 or more patients (n=2); only drug related SAE was 1 Grade 3 diverticulitis. No drug-related grade 4 AEs, AEs leading to study discontinuation, or on-study deaths reported kknpeawjxg (avhnuqykav )
Positive
14 May 2020
Not Applicable
Systemic Lupus Erythematosus
CD38 | CD20 | CD27 ...
-
hmpimpzgcx(yzjqanmayj) = pyrhunnjtj zeqjkxvsyi (rkkebrtetd )
Positive
14 Nov 2016
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free