Last update 01 Jul 2024

Lacutoclax

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
LP 108, LP-108
Target
Mechanism
Bcl-2 inhibitors(Apoptosis regulator Bcl-2 inhibitors)
Inactive Indication-
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-

Structure

Molecular FormulaC48H55ClN8O7S
InChIKeyCCDRQWAEZGRMTP-WJOKGBTCSA-N
CAS Registry2291166-56-6

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic Lymphocytic LeukemiaPhase 2
CN
-
Small Lymphocytic LymphomaPhase 2
CN
-
Myelodysplastic SyndromesPhase 1
CN
07 Feb 2023
Acute Myeloid LeukemiaPhase 1
US
06 Jul 2020
Acute Myeloid LeukemiaPhase 1
CN
06 Jul 2020
Acute Myeloid LeukemiaPhase 1
ES
06 Jul 2020
Acute Myeloid LeukemiaPhase 1
GB
06 Jul 2020
Adult Acute Myeloblastic LeukemiaPhase 1
US
06 Jul 2020
Adult Acute Myeloblastic LeukemiaPhase 1
ES
06 Jul 2020
Chronic Myelomonocytic LeukemiaPhase 1
US
06 Jul 2020
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
BTKi
33
LP-108 at dose levels from 20 mg/day to 800 mg/day
lkebtythyg(qyevpwcvxh) = not been reached yet xddsyqqqus (yfwhytzrbf )
Positive
14 May 2024
Phase 1
49
itapqguger(hvyeshvrmp) = tdbmkeuvou xbdtipibbh (qngxjlarft )
-
08 Jun 2023
Phase 1
32
qfjiombyej(vkalgriduz) = ukxkdjcwkq svngytmkmt (raoexubypp )
-
08 Jun 2023
qfjiombyej(vkalgriduz) = uwcdclbgtx svngytmkmt (raoexubypp )
Phase 1
19
tlzaelfjzc(rytonsgzvh) = zvrbvleyoi fduyofjcyr (duktzipvbi )
Positive
12 May 2022
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Clinical Trial

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Approval

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Regulation

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