Last update 17 Apr 2025

Umitrelimorgene Autodencel

Overview

Basic Info

Drug Type
Therapeutic vaccine, Dendritic cell vaccine
Synonyms
Cancer vaccine pp65, Cancer vaccine pp65 (Immunomic Therapeutics/Duke University), CMV pp65-LAMP mRNA-loaded dendritic cells
+ [8]
Action
inhibitors
Mechanism
CMV pp65 inhibitors(Cytomegalovirus pp65 Antigen inhibitors), LAMP-1 inhibitors(Lysosome-associated membrane glycoprotein 1 inhibitors)
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
GlioblastomaPhase 2
United States
09 Aug 2016
Glioblastoma MultiformePhase 2
United States
09 Aug 2016
Recurrent Malignant GliomaPhase 1
United States
05 Oct 2018
Recurrent MedulloblastomaPhase 1
United States
05 Oct 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
175
(Arm 1: pp65-shLAMP DC With GM-CSF and Td)
dtgtuytqlr(chyglqvcgq) = hfmblnrsys ksscyrsvta (wvhnzotsvw, 759.9)
-
14 Jan 2025
(Arm 2: pp65-flLAMP DC With GM-CSF and Td)
dtgtuytqlr(chyglqvcgq) = ghfllcckvy ksscyrsvta (wvhnzotsvw, 377.5)
Phase 2
6
jtxcarcddj(djrfudhyzb) = cfqujdaufn pyjzwdienp (jpdmkjgjeg, udsnptjnqj - hiswjeeokr)
-
08 Apr 2024
Phase 1
11
Td (tetanus toxoid)+CMV-DCs
vswqdlrmvl = orqqsnmdph lbdxbkxldr (qlurzbctko, gsymlrhrxf - yegcbufpbw)
-
28 Jan 2021
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Clinical Trial

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Approval

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Regulation

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