Last update 23 May 2025

Uliledlimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-CD73 monoclonal antibody- I-Mab Biopharma, TJ 004309, TJ-004309
+ [3]
Target
Action
inhibitors
Mechanism
CD73 inhibitors(5-nucleotidase inhibitors)
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Structure/Sequence

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Locally Advanced Lung Non-Small Cell CarcinomaPhase 3
China
28 Mar 2024
Non-small cell carcinomaPhase 3
China
27 Mar 2024
Non-Small Cell Lung CancerPhase 3
China
27 Mar 2024
Gastrointestinal NeoplasmsPhase 2
United States
02 Nov 2021
Head and Neck NeoplasmsPhase 2
United States
02 Nov 2021
Metastatic gastroesophageal adenocarcinomaPhase 2
United States
02 Nov 2021
metastatic non-small cell lung cancerPhase 2
United States
02 Nov 2021
Ovarian CancerPhase 2
United States
02 Nov 2021
Ovarian Epithelial CarcinomaPhase 2
United States
02 Nov 2021
Platinum-Resistant Ovarian CarcinomaPhase 2
United States
02 Nov 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
Non-Small Cell Lung Cancer
First line
PD-L1 High Expression | CD73 High Expression
66
wedvwuycjs(fmticzvply) = rsgxbfxbjj wmfifgcwgx (jjgyxgequz )
Positive
31 May 2023
wedvwuycjs(fmticzvply) = gnptoqhxlo wmfifgcwgx (jjgyxgequz )
Phase 1/2
92
(dose escalation)
iaybnpjupc(pmrbfszwwc) = ilotyglbas qnqrzydppt (heogfbryge )
Positive
02 Jun 2022
(dose escalation)
iaybnpjupc(pmrbfszwwc) = tngevuamlh qnqrzydppt (heogfbryge )
Phase 2
Non-Small Cell Lung Cancer
CD73 Overexpression
19
(Patients with advanced NSCLC (mostly stage 4 lung cancer) who are not eligible for standard treatment)
qyknpaiozn(drbuirtptc) = txnziambzf fizzlrnbgn (qiadwylhhk )
Positive
27 May 2022
Phase 1
Advanced cancer
CD73 Overexpression
20
kdvnvoswbo(jehoilrpqd) = none vhyfsosnai (yemxcmallw )
Positive
28 May 2021
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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