Drug Type Small molecule drug |
Synonyms Telatinib mesylate, BAY-57-9352, EOC-315 |
Action inhibitors, antagonists |
Mechanism PDGFRβ inhibitors(Platelet-derived growth factor receptor beta inhibitors), VEGFR2 antagonists(Vascular endothelial growth factor receptor 2 antagonists), VEGFR3 antagonists(Vascular endothelial growth factor receptor 3 antagonists) |
Therapeutic Areas |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationOrphan Drug (United States) |
Molecular FormulaC20H16ClN5O3 |
InChIKeyQFCXANHHBCGMAS-UHFFFAOYSA-N |
CAS Registry332012-40-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced Gastroesophageal Junction Adenocarcinoma | Phase 2 | United States | 28 Jul 2021 | |
Hepatocellular Carcinoma | Phase 2 | United States | 28 Jul 2021 | |
Esophageal Carcinoma | Phase 2 | United States | - | 15 Jul 2021 |
HER2 negative Gastroesophageal Junction Adenocarcinoma | Phase 2 | China | 25 Jan 2019 | |
Stomach Cancer | Phase 2 | United States | 08 Jan 2014 | |
Stomach Cancer | Phase 2 | Spain | 08 Jan 2014 | |
Advanced gastric carcinoma | Phase 2 | United States | 01 Jun 2009 | |
Advanced gastric carcinoma | Phase 2 | Spain | 01 Jun 2009 | |
Advanced Malignant Solid Neoplasm | Phase 1 | China | 25 Jul 2017 | |
Colorectal Cancer | Phase 1 | United States | 07 May 2008 |
Phase 2 | 16 | kkkhstusmw(qezbjqvuoi) = cfdyfpuore tzmcpoiopu (ynzilypumm, 133.69) View more | - | 10 Oct 2024 | |||
Phase 1 | 15 | btzmooderm(ovcoqdwhgu) = 2 (hospitalization due to high blood pressure) hsftciursr (zgezjqosps ) View more | Positive | 01 Jun 2019 | |||
Phase 2 | Gastrooesophageal junction cancer First line | 48 | kobeghmimw(hkmjaglqov) = epjqlahjzr zicrzzvxvy (aegyelqjzq ) View more | - | 20 May 2011 | ||
Phase 2 | - | vbmhitdsci(qcmjhyvumo) = ttylfgjyol nmzxxfskkc (fdmegxaimp ) | - | 01 Feb 2011 | |||
Phase 2 | 19 | ljmpvpwqrd(wtpaglaaen) = xcuxzszqpn wskrssmklc (gzbvqkylyu ) | - | 20 May 2010 |