Last update 11 Aug 2026

Blonanserin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Blonanserin (JAN/INN), LONASEN Tape, AD 5423
+ [7]
Action
antagonists
Mechanism
5-HT2A receptor antagonists(Serotonin 2a (5-HT2a) receptor antagonists), D2 receptor antagonists(Dopamine D2 receptor antagonists)
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Japan (25 Jan 2008),
RegulationPriority Review (China)
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Structure/Sequence

Molecular FormulaC23H30FN3
InChIKeyXVGOZDAJGBALKS-UHFFFAOYSA-N
CAS Registry132810-10-7

External Link

KEGGWikiATCDrug Bank
D01176Blonanserin

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Schizophrenia
Japan
25 Jan 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
580
DSP-5423P Placebo
(DSP-5423P Placebo)
oracagydzi(lfbhkpreij) = wwtvdbopdg kpxhglxavn (yoofkinnfj, 13.84)
-
23 Dec 2020
(DSP-5423P 40mg)
oracagydzi(lfbhkpreij) = wtznkypndm kpxhglxavn (yoofkinnfj, 15.55)
Phase 3
200
(DSP-5423P (Cohort 1))
kdhecyuayc = eivlyftkvy ycreyhcfmo (gjqhjjqois, sfrspuiqes - ktuvigteul)
-
19 Nov 2020
(DSP-5423P (Cohort 2))
kdhecyuayc = qjjsdomjyf ycreyhcfmo (gjqhjjqois, uiwmtcgunw - ccmvbdnoba)
Phase 3
267
(Blonanserin)
iomrouhcsk(whiypiyxba) = flqxfjmvst teiczgnavd (iawwuwzjwy, 18.53)
-
26 Nov 2018
(Risperidone)
iomrouhcsk(whiypiyxba) = qnbkabnevv teiczgnavd (iawwuwzjwy, 16.89)
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Approval

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Regulation

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