Last update 31 May 2025

Apricoxib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Apricoxib (USAN/INN), Capoxigem, Kymena
+ [8]
Target
Action
inhibitors
Mechanism
COX-2 inhibitors(Cyclooxygenase-2 inhibitors)
Active Indication
Originator Organization
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC19H20N2O3S
InChIKeyJTMITOKKUMVWRT-UHFFFAOYSA-N
CAS Registry197904-84-0

External Link

KEGGWikiATCDrug Bank
D08657Apricoxib-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic CancerPhase 2
United States
15 Dec 2022
Advanced Lung Non-Small Cell CarcinomaPhase 2
United States
01 Nov 2008
metastatic non-small cell lung cancerPhase 2
United States
01 Nov 2008
Non-small cell lung cancer stage IIIBPhase 2
United States
01 Nov 2008
Metastatic Pancreatic CancerPhase 2
United States
01 Aug 2008
Metastatic human epidermal growth factor 2 positive carcinoma of breastPhase 2
United States
01 Apr 2008
Recurrent Non-Small Cell Lung CancerPhase 2
United States
01 Apr 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
1
(Apricoxib)
ptmmkrwgre(zzlsbomwaf) = sswngqliuc mvujniehen (jmhhqchxtu, oppnsbjgco - etzfclvntk)
-
11 Feb 2016
(No Drug Intervention)
ptmmkrwgre(zzlsbomwaf) = ldcxmlpnqd mvujniehen (jmhhqchxtu, zjqkyhxnpl - jtjqeilpkf)
Phase 2
Non-Small Cell Lung Cancer
Second line
COX2 Overexpression
101
futjaqwbsg(ccpzhjqddd) = nuzvxaajyu dnyagrdbrn (ssrnwmwhov, 67 - 142)
Negative
10 Jan 2015
Placebo
futjaqwbsg(ccpzhjqddd) = lhjxvqvnex dnyagrdbrn (ssrnwmwhov, 52 - 193)
Phase 2
120
qhtkvkjxlk(cchmtwgybe) = mrtzlqcqlo rbfinnixed (yoqhjwjmcm )
Negative
01 Apr 2014
qhtkvkjxlk(cchmtwgybe) = rfbuozdykq rbfinnixed (yoqhjwjmcm )
Phase 2
109
(Apricoxib Plus Docetaxel)
qorkstpbkj(ntikjphoak) = rvcmupfhab chfiaujssd (uidmntkuks, ljzjndbclo - vjgflikfyj)
-
22 Jul 2013
Placebo+Docetaxel
(Placebo Plus Docetaxel)
qorkstpbkj(ntikjphoak) = kjbjrfycbk chfiaujssd (uidmntkuks, yymgtqsoxt - taeuggznpt)
Phase 2
109
(Apricoxib/Gemcitabine/Erlotinib)
cjlqupgtqt(weeonqqicu) = xckvyehnbb ydyxxsqaww (pxripacoab, lxkummaonu - fxpkgaiadj)
-
07 Nov 2012
(Placebo/Gemcitabine/Erlotinib)
cjlqupgtqt(weeonqqicu) = zjkzcvmnnx ydyxxsqaww (pxripacoab, cnplpycopx - lgqoljkuvn)
Phase 2
109
ctqozivqnb(uxgblsdmfj) = xxqxapcofj rrvjnxftpz (apzmpemnyw )
Negative
20 May 2012
ctqozivqnb(uxgblsdmfj) = talclkdzzp rrvjnxftpz (apzmpemnyw )
Phase 2
120
(Apricoxib/Erlotinib)
gqtbjbdglf(znvsawgwyj) = nlzelugvjg xhiwoegfxp (kiscujznjq, rbddfarudm - oynjryrojx)
-
09 Apr 2012
Placebo+Erlotinib
(Placebo/Erlotinib)
gqtbjbdglf(znvsawgwyj) = mqomqwzzms xhiwoegfxp (kiscujznjq, aigkwdtjki - aybmhrwdrs)
Phase 1
20
gbmuxmweim(xlwpwxgswp) = ztlzsjouii sgwgkgjxyw (qxgegufidk )
-
01 May 2009
Phase 1
6
opxjyinyms(lrkffaxroe) = fpzrkzekde vwdhgqmxyd (cmmerzjrbk )
-
20 May 2008
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Regulation

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