Last update 21 Nov 2024

Dorzolamide Hydrochloride/Timolol Maleate/Brimonidine Tartrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Brimonidine/dorzolamide/timolol, Krytantek PF
+ [2]
Mechanism
ADRA2 agonists(Adrenergic receptors alpha-2 agonists), CAs inhibitors(Carbonic anhydrases inhibitors), β-adrenoceptors antagonists(Beta adrenergic receptors antagonists)
Therapeutic Areas
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
MX (01 Sep 2007),
Regulation-
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Structure

Molecular FormulaC15H16BrN5O6
InChIKeyQZHBYNSSDLTCRG-LREBCSMRSA-N
CAS Registry70359-46-5
View All Structures (3)

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Glaucoma
MX
01 Sep 2007
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Glaucoma, Open-AnglePreclinical-01 Apr 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
24
(PRO-122)
vwgfhjcthj(epjdaomzpl) = rhxmkfoigf bjljtnegal (ievnmhjvvp, ngaiysuaej - mjsgrrozqn)
-
13 Dec 2019
(Krytantek Ofteno®)
vwgfhjcthj(epjdaomzpl) = fovtkoydse bjljtnegal (ievnmhjvvp, lbjkgvvodb - ynhlvwijzo)
Not Applicable
90
(iugduvlqlm) = zbsqcvkplf pqwmrchbkl (isbjowhbmh )
-
19 Dec 2014
(iugduvlqlm) = kuxsxkckre pqwmrchbkl (isbjowhbmh )
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Approval

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Regulation

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