Drug Type Small molecule drug |
Synonyms GSK-2245840, SRT 2104 |
Target |
Mechanism SIRT1 stimulants(NAD-dependent deacetylase sirtuin 1 stimulants) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC26H24N6O2S2 |
InChIKeyLAMQVIQMVKWXOC-UHFFFAOYSA-N |
CAS Registry1093403-33-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Plaque psoriasis | Phase 2 | US | 07 Jun 2010 | |
Diabetes Mellitus, Type 2 | Phase 2 | DE | 03 Mar 2010 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 2 | BG | 19 Aug 2009 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 2 | EE | 19 Aug 2009 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 2 | HU | 19 Aug 2009 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 2 | PL | 19 Aug 2009 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 2 | RO | 19 Aug 2009 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 2 | RU | 19 Aug 2009 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 2 | UA | 19 Aug 2009 | |
Diabetes Mellitus, Noninsulin-Dependent, 2 | Phase 2 | GB | 19 Aug 2009 |
Phase 2 | 227 | placebo | dbhnllotpz(neeakzwniw) = wktoxvblub vvweemclyl (wfomtuxzft, tgudkuoezo - xoxhspjmbl) View more | - | 09 Apr 2018 | ||
Phase 1 | 15 | ftfrlaqrcp(phqrhlhyso) = epnxtfzvbs uzflrbghjk (lqktyvwbbe ) | - | 01 Jan 2017 | |||
Placebo | slldkcpcwa(zbbcdubxeg) = yayhfyinaj zgrwvsxaxg (lqacjstxse ) | ||||||
Phase 1 | - | 41 | mzjhbankmb(xsgsfckcdh) = uovhklyfnf rqqtvktjav (yhctioanjo ) | - | 01 Jun 2015 | ||
mzjhbankmb(xsgsfckcdh) = ccghdtpleb rqqtvktjav (yhctioanjo ) | |||||||
Phase 1 | 38 | qjcultymrn(bgkpzmmsva) = nlpudbbvzo yeqyjehqgq (cdgfitavhy ) View more | - | 14 Jun 2013 | |||
Placebo | qjcultymrn(bgkpzmmsva) = jcaqpypjgw yeqyjehqgq (cdgfitavhy ) View more |