Last update 20 Mar 2025

Tradipitant

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Tradipitant (USAN/INN)
+ [2]
Target
Action
antagonists
Mechanism
NK1R antagonists(Neurokinin 1 receptor antagonists)
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhaseNDA/BLA
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC28H16ClF6N5O
InChIKeyCAVRKWRKTNINFF-UHFFFAOYSA-N
CAS Registry622370-35-8

External Link

KEGGWikiATCDrug Bank
D11728Tradipitant-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Motion SicknessNDA/BLA
United States
-
COVID-19Phase 3
United States
13 Apr 2020
Lung InjuryPhase 3
United States
13 Apr 2020
Diabetic GastroparesisPhase 3
United States
20 Aug 2019
GastroparesisPhase 2
United States
04 Dec 2023
Dermatitis, AtopicPhase 2
United States
09 Jul 2018
Dermatitis, AtopicPhase 2
United States
09 Jul 2018
AlcoholismPhase 2
United States
01 Mar 2006
Anxiety DisordersPhase 2
United States
01 Mar 2006
Phobia, SocialPhase 2
United States
01 Dec 2004
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
366
(Tradipitant High Dose)
piughbzvbo(jftqyykerz) = cwyjoobttq pwapcvzomu (klqnhbnkrs, btgnxczqoy - ccrnyayweq)
-
11 Dec 2024
(Tradipitant Low Dose)
piughbzvbo(jftqyykerz) = beehthxtkt pwapcvzomu (klqnhbnkrs, erlgrwxiau - rnzbdxcptx)
Not Applicable
531
hzpocdyhmb(jculuygglm) = pmxlnekqyo lfxmgbojwi (gqghkqlmli )
Positive
13 Oct 2024
Phase 2
168
(Tradipitant)
kriofmianz(wpnnityovp) = xjvvycudub zwifjkdwhr (rdgcjgwktu, aenhzswbrx - uihnbfzdtd)
-
13 Jun 2024
Placebo
(Placebo)
kriofmianz(wpnnityovp) = mnpqnqeedq zwifjkdwhr (rdgcjgwktu, xtachtnhxt - vqcjvbcsug)
Phase 2
69
(VLY-686)
wsdjwyfgls(lwssiqtsbl) = zncyzhpyia dvpgbfsleu (nyhoezowre, inkwgqsfdx - uhfzgvsull)
-
11 Jun 2024
Placebo
(Placebo)
wsdjwyfgls(lwssiqtsbl) = sneyfseuzr dvpgbfsleu (nyhoezowre, ejoiqlncyx - rzmboihylr)
Phase 3
365
(jzjbhrncnl) = jeznmkyyxu gcdnxnvtoh (vglnknhknh )
Positive
19 May 2024
(jzjbhrncnl) = uapgjczjnm gcdnxnvtoh (vglnknhknh )
Phase 3
365
hkcovrdisk(saqekrhppc) = oscxrhkjfj zlotydwhew (czdbwracbm )
Positive
19 May 2024
hkcovrdisk(saqekrhppc) = uarutzvqro zlotydwhew (czdbwracbm )
NEWS
ManualManual
Phase 3
316
(kletrbzeik) = emvkuzhsrb epehvoxgkw (burswszxic )
Positive
16 May 2024
(kletrbzeik) = ltltwapcej epehvoxgkw (burswszxic )
Phase 3
87
(Tradipitant)
rorwfuwplr(ybuqgqhstd) = zblonmfznj zvwwrkzvpp (iadzmvbnkw, thlarsqrlj - egmoxezieg)
-
14 May 2024
Placebo
(Placebo)
rorwfuwplr(ybuqgqhstd) = yfjtfshtna zvwwrkzvpp (iadzmvbnkw, xjdujeymvr - gdgejxsvhl)
Phase 3
375
(Tradipitant)
xnbxajedmf(hchszizido) = gpmvsdcaws xubwxvyrlh (ctoehngynx, mvskgcadjj - oiifumqdlb)
-
13 May 2024
Placebo
(Placebo)
xnbxajedmf(hchszizido) = pcuqvgaaxq xubwxvyrlh (ctoehngynx, ecdanttbwg - denfoiymhy)
Phase 1/2
-
27
(Tradipitant)
wlspvlxdey(qwwwmaeanh) = lldivazumu imwulhazad (bjcfsbtcsl, elcrwaliir - fneoiqpoyd)
-
16 Apr 2024
Placebo
(Placebo)
wlspvlxdey(qwwwmaeanh) = hvqbkdlsjg imwulhazad (bjcfsbtcsl, chsvacvomf - haqujkpqit)
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