Last update 30 Nov 2024

TAB014

Overview

Basic Info

Drug Type
Recombinant protein
Synonyms
TAB014 monoclonal antibody injection, TAB 014, TAB-014
+ [1]
Target
VEGF
Mechanism
VEGF inhibitors(Vascular endothelial growth factor inhibitors)
Therapeutic Areas
Congenital DisordersEye Diseases
Active Indication
Wet age-related macular degeneration
Inactive Indication
Glycogen Storage Disease Type II
Originator Organization
TOT BIOPHARM International Co. Ltd.TOT BIOPHARM International Co. Ltd.
Active Organization
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.TOT BIOPHARM International Co. Ltd.TOT BIOPHARM International Co. Ltd.Tot Biopharm Co. Ltd.Tot Biopharm Co. Ltd.
Inactive Organization
Lee's Pharmaceutical Holdings Ltd.Lee's Pharmaceutical Holdings Ltd.
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Related

4
Clinical Trials associated with TAB014
NCT05461339 / RecruitingPhase 3
A Phase III, Randomized, Multicenter, Doubled-blind Clinical Trial Comparing the Efficacy and Safety of TAB014 and Lucentis in Neovascular Age-related Macular Degeneration (nAMD) Patients
CTR20211015 / CompletedPhase 3
评价TAB014对比雷珠单抗（诺适得®）在新生血管性年龄相关性黄斑变性患者中有效性和安全性的多中心、随机、双盲的III期临床研究
[Translation] A multicenter, randomized, double-blind Phase III clinical study to evaluate the efficacy and safety of TAB014 versus ranibizumab (Lucentis®) in patients with neovascular age-related macular degeneration
CTR20180360 / CompletedPhase 1
TAB014治疗湿性(新生血管性)年龄相关性黄斑变性（AMD）的I期临床研究
[Translation] Phase I clinical study of TAB014 for the treatment of wet (neovascular) age-related macular degeneration (AMD)
100 Clinical Results associated with TAB014
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100 Translational Medicine associated with TAB014
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100 Patents (Medical) associated with TAB014
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100 Deals associated with TAB014
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Wet age-related macular degenerationPhase 3
US
Tot Biopharm Co. Ltd.Tot Biopharm Co. Ltd.
12 May 2022
Glycogen Storage Disease Type IIPhase 1
CN
Lee's Pharmaceutical Holdings Ltd.Lee's Pharmaceutical Holdings Ltd.
15 Jun 2018
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Clinical Result

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Approval

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Regulation

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