Last update 21 Nov 2024

Delpacibart Etedesiran

Overview

Basic Info

Drug Type
Antibody oligonucleotide conjugates
Synonyms
Del-desiran
+ [1]
Mechanism
DMPK modulators(DM1 protein kinase modulators), TfR1 antagonists(Transferrin receptor protein 1 antagonists)
Active Indication
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (EU), Fast Track (US), Breakthrough Therapy (US)
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Structure

Molecular FormulaC18H28N2O4
InChIKeyQTALRNANPCLRGM-UHFFFAOYSA-N
CAS Registry827615-02-1
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Myotonic DystrophyPhase 3
DE
30 May 2024
Myotonic DystrophyPhase 3
IT
30 May 2024
Myotonic DystrophyPhase 3
ES
30 May 2024
Myotonic DystrophyPhase 3
IE
30 May 2024
Myotonic DystrophyPhase 3
FR
30 May 2024
Myotonic DystrophyPhase 3
DK
30 May 2024
Myotonic DystrophyPhase 3
GB
30 May 2024
Myotonic DystrophyPhase 3
JP
30 May 2024
Myotonic DystrophyPhase 3
US
30 May 2024
Myotonic DystrophyPhase 3
NL
30 May 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
37
(vzzpsyrekw) = ngfallzafm jwiddidjev (tcexjjzgxl )
Positive
01 Feb 2024
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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