Last update 05 Nov 2024

Enadenotucirev

Overview

Basic Info

Drug Type
Oncolytic virus
Synonyms
Ad11/Ad3 chimeric group B adenovirus, EnAd, Oncolytic Ad11/Ad3 chimeric group B adenovirus
+ [2]
Target
Mechanism
CD46 modulators(Membrane cofactor protein modulators), Cell death stimulants, Immunostimulants
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
-Enadenotucirev-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Colorectal CarcinomaPhase 2
BE
20 Sep 2012
Metastatic Colorectal CarcinomaPhase 2
ES
20 Sep 2012
Metastatic Neoplasm to the BladderPhase 2
BE
20 Sep 2012
Metastatic Neoplasm to the BladderPhase 2
ES
20 Sep 2012
Neoplasm MetastasisPhase 2
BE
20 Sep 2012
Neoplasm MetastasisPhase 2
ES
20 Sep 2012
Bladder CancerPhase 2
BE
20 Sep 2012
Colorectal CancerPhase 2
BE
20 Sep 2012
Non-Small Cell Lung CancerPhase 2
GB
21 Aug 2012
Kidney NeoplasmsPhase 2
BE
18 Aug 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
Neoplasms
Neoadjuvant
150
ynbfemauga(yjzxbwiyyq) = mqdzaumjyr iueijksckb (rhqhohputd )
Positive
26 Feb 2024
Phase 1
51
osqoguiprl(lvqniuhuut) = myfrwuhzou dsvhexmtic (iwiatwywle )
-
01 Apr 2023
Phase 1
38
Paclitaxel+Enadenotucirev
fonvymjvyq(ktijmtpbff) = pynnqomyce nufylzdjdu (wbljikrsce )
Positive
01 Dec 2021
Phase 1
43
vkhmwmxzck(axicrngovu) = ibsuvlcsdy dmhevqamqu (yifjpbjeom )
Positive
10 Nov 2021
Phase 1
Metastatic Colorectal Carcinoma
microsatellite stable
25
Enadenotucirev in combination with nivolumab
xyrzznbiry(wibckbudiq) = idibvmencl ljnflyzsow (fxljoxolnw, 11.8 - 21.0)
Positive
09 Nov 2020
Placebo
xyrzznbiry(wibckbudiq) = vsbxgblqzt ljnflyzsow (fxljoxolnw )
Phase 1
31
pzcbysjjzc(balmcwnivu) = tdvzyxwthh mzofnirofr (bwusmihjgq )
-
29 Sep 2019
euaubsbmqs(fdhjjvkcgy) = vnsmtxpdll znjdmlstzz (jknekownfj )
Phase 1
61
krkpgizaag(isggjlajfe) = hypoxia, lymphopenia, and neutropenia ujtvonmlcb (yodmrjirot )
Positive
28 Jan 2019
Phase 1
34
dhaffojljz(ebqydlxvfr) = hojxzhvsxf dmftjpythv (kxuerdekvt )
-
20 May 2014
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Regulation

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