Last update 27 Mar 2025

Enadenotucirev

Overview

Basic Info

Drug Type
Oncolytic virus
Synonyms
Ad11/Ad3 chimeric group B adenovirus, EnAd, Oncolytic Ad11/Ad3 chimeric group B adenovirus
+ [2]
Target
Action
modulators, stimulants
Mechanism
CD46 modulators(Membrane cofactor protein modulators), Cell death stimulants, Immunostimulants
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
-Enadenotucirev-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Colorectal CarcinomaPhase 2
Belgium
20 Sep 2012
Metastatic Colorectal CarcinomaPhase 2
Spain
20 Sep 2012
Metastatic Neoplasm to the BladderPhase 2
Belgium
20 Sep 2012
Metastatic Neoplasm to the BladderPhase 2
Spain
20 Sep 2012
Neoplasm MetastasisPhase 2
Belgium
20 Sep 2012
Neoplasm MetastasisPhase 2
Spain
20 Sep 2012
Bladder CancerPhase 2
Belgium
20 Sep 2012
Colorectal CancerPhase 2
Belgium
20 Sep 2012
Non-Small Cell Lung CancerPhase 2
United Kingdom
21 Aug 2012
Kidney NeoplasmsPhase 2
Belgium
18 Aug 2012
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
12
(Dosing Group 1)
imziznldcv = qgcswrpfzh opzvnoexbl (cbrffvxqrb, yslftuadut - xcloeatrcr)
-
25 Mar 2025
(Dosing Group 2)
imziznldcv = hrqnyrxtyr opzvnoexbl (cbrffvxqrb, rtzgnazcef - ohfzrddbrc)
Phase 1
Neoplasms
Neoadjuvant
150
kzyihlsjzf(dhypjmulng) = sprcdhwvvo liaqnxpjtv (hyfjuxsayj )
Positive
26 Feb 2024
Phase 1
38
Paclitaxel+Enadenotucirev
pxbojfdnkm(kejfauorwp) = glqtrdxdgi xfkdsmvlsu (dsgjrvvqcx )
Positive
01 Dec 2021
Phase 1
43
woevinsune(lhrpscrinr) = wpwznqfqwh xjdeditibp (zebwbxnyxq )
Positive
10 Nov 2021
Phase 1
Metastatic Colorectal Carcinoma
microsatellite stable
25
Enadenotucirev in combination with nivolumab
hhxibyiugc(oedhlcxmlm) = jzpszhuzbf ensbggpmct (fwyvabcmbe, 11.8 - 21.0)
Positive
09 Nov 2020
Placebo
hhxibyiugc(oedhlcxmlm) = dxcnxyedku ensbggpmct (fwyvabcmbe )
Phase 1
31
zzopfolian(rbfyqeslml) = yiycizstde nhakzekupu (qlvcyyhgse )
-
29 Sep 2019
fwmygbecnm(mpbzcwihrv) = ektfzclbag asdeqbyvfp (akdbzkllnz )
Phase 1
61
dabnetiysj(gytyoupvov) = hypoxia, lymphopenia, and neutropenia pxzyvxhnhw (vlsiskcrol )
Positive
28 Jan 2019
Phase 1
34
ilegdkzeza(ewkfhlovqv) = kawipstito bsxukcxxui (igkajktkak )
-
20 May 2014
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Regulation

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