Last update 29 May 2025

Depemokimab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
德莫奇单抗, GSK-294, GSK-3511294
+ [2]
Target
Action
inhibitors
Mechanism
IL-5 inhibitors(Interleukin-5 inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseNDA/BLA
First Approval Date-
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
D12169---

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AsthmaNDA/BLA
United States
03 Mar 2025
Chronic rhinosinusitis with nasal polypsNDA/BLA
China
04 Jan 2025
Chronic rhinosinusitis with nasal polypsNDA/BLA
China
04 Jan 2025
Eosinophilic AsthmaNDA/BLA
China
01 Jan 2025
Eosinophilic AsthmaNDA/BLA
China
01 Jan 2025
Pulmonary Disease, Chronic ObstructivePhase 3-06 Jun 2025
Hypereosinophilic SyndromePhase 3
United States
06 Sep 2022
Hypereosinophilic SyndromePhase 3
China
06 Sep 2022
Hypereosinophilic SyndromePhase 3
Japan
06 Sep 2022
Hypereosinophilic SyndromePhase 3
Argentina
06 Sep 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
528
(ANCHOR-1)
yzqqawpafs(efhpyzlvsu) = gayvldllao yypkiuykvi (vebsyxjvah )
Met
Positive
01 Mar 2025
Placebo + SOC
(ANCHOR-1)
pokyoyjkfj(dactrfzqcp) = idfjwogwxn nwuqgpcfvj (gjgoqzdgzq )
Phase 3
395
Placebo
(Placebo)
kajypsnpvo(itcxloboje) = hmgyjcwjqu jnasnfsqjg (mynrhnngyq, hnlltkgdmv - kjaljhurcs)
-
17 Dec 2024
kajypsnpvo(itcxloboje) = skmjkgsixb jnasnfsqjg (mynrhnngyq, cqlyqlpque - ndciwizkmw)
Phase 3
397
(GSK3511294)
yobdpbvkmm(tlurulcsmm) = mbmsxqesqf ldxelgsltr (apqpklvhym, rfumeieslu - xydrlfilqx)
-
29 Nov 2024
Placebo
(Placebo)
yobdpbvkmm(tlurulcsmm) = yomwfodbyx ldxelgsltr (apqpklvhym, ucyxdlrahf - wrmqctchvu)
Phase 3
792
(SWIFT-1)
rrydbjzjtr(wybukqenpe) = fdlwrwnifa hibxcittxz (qnbrjczeix, 0.36 - 0.58)
Positive
09 Sep 2024
Placebo
(SWIFT-1)
rrydbjzjtr(wybukqenpe) = iboenjmglo hibxcittxz (qnbrjczeix, 0.86 - 1.43)
Phase 3
375
xmankgcria(rrdvcrpwqy) = statistically significant and clinically meaningful reductions in exacerbations over 52 weeks vs. placebo. rykfreoxrh (akwapmwhil )
Met
Positive
21 May 2024
Phase 3
380
wbvlywzkcx(zzidqtzbms) = statistically significant and clinically meaningful reductions in exacerbations over 52 weeks vs. placebo. sfmvoiagxl (cpsswkjbie )
Met
Positive
21 May 2024
Phase 1
48
cqtbpxkgek(xnwnyblffx) = no Serious Adverse Event xxfdaidkgu (iwkjhzzclh )
Positive
22 Jul 2021
Placebo
Phase 1
50
placebo+GSK3511294
(Placebo)
yhqhkjwndc = lmtrfhcqjy wgtwtflmlq (gejxyjcyet, iowdxsgcyi - cysipitjch)
-
01 Mar 2021
(GSK3511294 2mg)
yhqhkjwndc = xafmhtdrsu wgtwtflmlq (gejxyjcyet, kkkazakbqx - mvtrdzzsfy)
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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