Drug Type Monoclonal antibody |
Synonyms MSB 0254 |
Target |
Mechanism VEGFR2 antagonists(Vascular endothelial growth factor receptor 2 antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Solid tumor | Phase 2 | CN | - | |
Advanced Malignant Solid Neoplasm | Phase 1 | CN | 01 Apr 2020 |
Phase 1 | 22 | fpxgxflcrm(isozxmlbal) = One DLT was reported in 12mg/kg Q2W dose cohort. A subject with intra-cholangial carcinoma developed G3 (grade 3) upper gastrointestinal hemorrhage on the C1D13. The adverse event was resolved after symptomatic treatment. qgulnvcbgm (vxtbsdgfto ) View more | Positive | 02 Jun 2022 | |||
Phase 1 | 19 | pkdpakekea(kgyagwvlwo) = 高血压 6例(31.6%),中性粒细胞计数降低、γ-谷氨酰转移酶升高 和天门冬氨酸氨基转移酶升高各4例(21.1%),白细胞计数 降低、血小板计数降低、蛋白尿和贫血各3例(15.8%),上 消化道出血、牙龈出血和血尿症各2例(10.5%) fglphcpqex (gmmmboeavt ) View more | Positive | 25 Sep 2021 | |||
Phase 1 | 16 | edissorilx(yiqmeaswax) = qdzaptzwyy omrmnwbgsu (xbkbjurimy ) | - | 25 Sep 2021 |