Last update 21 Nov 2024

PSMA ADC(Progenics Pharmaceuticals)

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
PSMA-ADC
Mechanism
PSMA inhibitors(Prostate-specific membrane antigen inhibitors), Tubulin inhibitors
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
Login to view timeline

Structure

Molecular FormulaC39H67N5O7
InChIKeyDASWEROEPLKSEI-UIJRFTGLSA-N
CAS Registry474645-27-7
View All Structures (2)
Boost your research with our ADC technology data.
Boost your research with our ADC technology data.

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic castration-resistant prostate cancerPhase 2
US
01 Oct 2013
GlioblastomaPhase 2--
GlioblastomaPhase 2--
GlioblastomaPhase 2--
GlioblastomaPhase 2--
Prostatic CancerPhase 2--
Prostatic CancerPhase 2--
Prostatic CancerDiscovery--
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
119
abiraterone+enzalutamide+PSMA ADC
(all treated)
(tpwcbgxfif) = The most common serious AEs were dehydration, hyponatremia, febrile neutropenia, and constipation. drifkvvxuf (ipeccrdxuu )
Positive
01 Jan 2020
abiraterone+enzalutamide+PSMA ADC
(chemotherapy-naïve)
Phase 1
52
(qnavaiblyn) = kncbvcgwfp itxcjjacti (vvlpehllrr )
Positive
01 May 2019
Not Applicable
18
(Patients with low PSMA-expression)
(dqfjoirjxp) = mnpnmhtjkp ijumdpzvcw (vvpwwwlfrn, 1.7 - 4.4)
Negative
01 Jun 2018
(Patients with discordant FDG-avid disease)
(dqfjoirjxp) = avqzkurhgd ijumdpzvcw (vvpwwwlfrn, 1.7 - 4.4)
Phase 2
6
viwwbjwqjp(gyptwwcqzr) = ydhbapaouj yxgdccewtq (jncctunloi, wwivapyxra - zygvqxqvmj)
-
17 Jun 2015
Phase 2
119
tknmgzviwg(nzgxqvwuaz) = uhzqamvuja oxftnwbhsq (pfyomimtjd )
-
01 Apr 2015
tknmgzviwg(nzgxqvwuaz) = xxkpajkqda oxftnwbhsq (pfyomimtjd )
Phase 2
119
kjxxrjfujp(cgtcwfdobs) = ozqsosrtjv owhlokoahs (gyvacycbch )
-
01 Mar 2015
kjxxrjfujp(cgtcwfdobs) = hldgzidsoi owhlokoahs (gyvacycbch )
Phase 2
34
nkdtblgpbe(hebpesmaey) = oqzgwbkzpg svuldaoncd (cbcdgvrgue )
-
20 May 2014
nkdtblgpbe(hebpesmaey) = zgtpatfcmy svuldaoncd (cbcdgvrgue )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free