Last update 23 Jan 2025

Tenofovir Alafenamide Fumarate/Elvitegravir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
TAF/EVG, Tenofovir Alafenamide/Elvitegravir
Target
HIV integrase x RT
Mechanism
HIV-1 integrase inhibitors(HIV integrase inhibitors), RT inhibitors(Reverse transcriptase inhibitors)
Therapeutic Areas
Immune System DiseasesInfectious DiseasesUrogenital Diseases
Active Indication
HIV Infections
Inactive Indication-
Originator Organization
Eastern Virginia Medical SchoolEastern Virginia Medical School
Active Organization
Eastern Virginia Medical SchoolEastern Virginia Medical School
Inactive Organization
National Institute of Allergy & Infectious Diseases
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC23H23ClFNO5
InChIKeyJUZYLCPPVHEVSV-LJQANCHMSA-N
CAS Registry697761-98-1
View All Structures (2)

Related

2
Clinical Trials associated with Tenofovir Alafenamide Fumarate/Elvitegravir
NCT06274398
/ RecruitingPhase 1IIT
A Double-Blind, Placebo-Controlled, Randomized Phase 1 Study to Evaluate the Safety and Pharmacokinetics of Rectally Administered Tenofovir Alafenamide/Elvitegravir Inserts
NCT04047420
/ CompletedPhase 1IIT
A Phase 1 Open Label Safety and Pharmacokinetic Study of Rectal Administration of a Tenofovir Alafenamide/Elvitegravir Insert at Two Dose Levels
100 Clinical Results associated with Tenofovir Alafenamide Fumarate/Elvitegravir
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100 Translational Medicine associated with Tenofovir Alafenamide Fumarate/Elvitegravir
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100 Patents (Medical) associated with Tenofovir Alafenamide Fumarate/Elvitegravir
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100 Deals associated with Tenofovir Alafenamide Fumarate/Elvitegravir
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R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT04047420 (MTN-039, Pubmed)
ManualManual
Phase 1
HIV Infections
-
(uprdmversi) = adoalfolvn aeznswetkz (vxeyscusue )
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Positive
24 Apr 2024
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Approval

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Regulation

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