Last update 01 Jun 2025

Raxatrigine hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Raxatrigine, Vixotrigine, Vixotrigine Hydrochloride(USAN)
+ [12]
Target
Action
blockers
Mechanism
Nav1.7 blockers(Sodium channel protein type IX alpha subunit blockers)
Originator Organization
Active Organization
Inactive Organization-
License Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC18H20ClFN2O2
InChIKeyHEPUBAGOKRIZEO-PPPUBMIESA-N
CAS Registry934240-31-0

External Link

KEGGWikiATCDrug Bank
-Raxatrigine hydrochloride-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Trigeminal NeuralgiaPhase 3
Austria
01 Feb 2017
NeuralgiaPhase 3--
Nonproliferative diabetic retinopathyPhase 2
Bulgaria
31 May 2018
Nonproliferative diabetic retinopathyPhase 2
Canada
31 May 2018
Nonproliferative diabetic retinopathyPhase 2
Czechia
31 May 2018
Nonproliferative diabetic retinopathyPhase 2
Denmark
31 May 2018
Nonproliferative diabetic retinopathyPhase 2
France
31 May 2018
Nonproliferative diabetic retinopathyPhase 2
Germany
31 May 2018
Nonproliferative diabetic retinopathyPhase 2
Greece
31 May 2018
Nonproliferative diabetic retinopathyPhase 2
Hungary
31 May 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
265
crkdwfhquj(ztkkuouewc): odds ratio = 2.6 (95% CI, 0.97 - 6.99), P-Value = 0.058
Positive
01 May 2023
Placebo
Phase 2
29
zqhrylrbcx(tpwdzhrqkl) = nvqupdexez szndwaaiwc (pdecsaclxq )
Positive
01 Apr 2017
zqhrylrbcx(tpwdzhrqkl) = lfuumsjuux szndwaaiwc (pdecsaclxq )
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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