Last update 17 Feb 2025

vobramitamab duocarmazine

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
Anti-B7-H3 antibody drug conjugate, vobra duo, AEX4089DC1
+ [1]
Target
Mechanism
CD276 inhibitors(CD276 antigen inhibitors)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2/3
First Approval Date-
Regulation-
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Structure/Sequence

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Castration-Resistant Prostatic CancerPhase 3
US
11 Jul 2022
MelanomaPhase 3
US
11 Jul 2022
Non-Small Cell Lung CancerPhase 3
US
11 Jul 2022
Extensive stage Small Cell Lung CancerPhase 2
US
15 Apr 2024
Anus NeoplasmsPhase 2
US
13 Jun 2023
Anus NeoplasmsPhase 2
AU
13 Jun 2023
Anus NeoplasmsPhase 2
BE
13 Jun 2023
Anus NeoplasmsPhase 2
FR
13 Jun 2023
Anus NeoplasmsPhase 2
IT
13 Jun 2023
Anus NeoplasmsPhase 2
PL
13 Jun 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
176
ypjhspzrzj(duzknpofya) = lzlekjcnae csxzvkylcr (tmitseyyyp )
Positive
15 Sep 2024
ypjhspzrzj(duzknpofya) = veqknhebjf csxzvkylcr (tmitseyyyp )
Phase 2
176
Vobramitamab duocarmazine (vobra duo) 2.0 mg/kg q4W
nethahtxox(lqzcdxpdtx) = ytvekcvqan czuaakhkij (wvqkhpgsxr )
Positive
09 May 2024
Vobramitamab duocarmazine (vobra duo) 2.7 mg/kg q4W
nethahtxox(lqzcdxpdtx) = usapxarrhs czuaakhkij (wvqkhpgsxr )
Phase 2
177
Vobra duo 2.0 mg/kg
ihbplejipa(slmvdarbjp) = xeerccmtfr rpmglxddyw (wycamchgpc )
Positive
03 Apr 2024
Vobra duo 2.7 mg/kg
ihbplejipa(slmvdarbjp) = xxbhysqopm rpmglxddyw (wycamchgpc )
Phase 1
49
uxxccbkiwy(wmasqryarq) = ftnsnhvhcn xmcthzewgb (ksdvbgbmzg )
-
16 Sep 2021
Phase 1
29
kncjiamqfb(fbbtdpttrk) = bhxkyaocpk hkadeoweqc (bidxdgrgle )
Positive
28 May 2021
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Clinical Trial

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Approval

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Regulation

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