Drug Type Small molecule drug |
Synonyms S 055746, S-55746, SERVIER-1 |
Target |
Action inhibitors |
Mechanism Bcl-2 inhibitors(Apoptosis regulator Bcl-2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
Molecular FormulaC43H42N4O6 |
InChIKeyVYXJULKGMXJVGI-XIFFEERXSA-N |
CAS Registry1448584-12-0 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Follicular Lymphoma | Phase 1 | United States | 16 Nov 2015 | |
Follicular Lymphoma | Phase 1 | Austria | 16 Nov 2015 | |
Follicular Lymphoma | Phase 1 | France | 16 Nov 2015 | |
Follicular Lymphoma | Phase 1 | Germany | 16 Nov 2015 | |
Mantle-Cell Lymphoma | Phase 1 | United States | 16 Nov 2015 | |
Mantle-Cell Lymphoma | Phase 1 | Austria | 16 Nov 2015 | |
Mantle-Cell Lymphoma | Phase 1 | France | 16 Nov 2015 | |
Mantle-Cell Lymphoma | Phase 1 | Germany | 16 Nov 2015 | |
Acute Myeloid Leukemia | Phase 1 | Australia | 01 Jan 2015 | |
Acute Myeloid Leukemia | Phase 1 | Australia | 01 Jan 2015 |
Phase 1 | 37 | cslqrwjaml(ixkltqjdcc) = lymphopenia (n = 4), anemia (n = 3), and disease progression (n = 3) vxondbayky (kkoytyyire ) View more | Positive | 07 Jun 2017 | |||
Phase 1 | 34 | nbljbssrdw(ggyexuvjad) = 2 pts invljdpbwh (nbpjrybtde ) View more | Positive | 18 May 2017 |