Drug Type Small molecule drug |
Synonyms Evacetrapib (USAN) |
Target |
Mechanism CETP inhibitors(Cholesteryl ester transfer protein inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
RegulationSpecial Review Project (CN) |
Molecular FormulaC31H36F6N6O2 |
InChIKeyIHIUGIVXARLYHP-YBXDKENTSA-N |
CAS Registry1186486-62-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10121 | Evacetrapib | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Vascular Diseases | Phase 3 | TW | 01 Oct 2012 | |
Vascular Diseases | Phase 3 | BG | 01 Oct 2012 | |
Vascular Diseases | Phase 3 | MX | 01 Oct 2012 | |
Vascular Diseases | Phase 3 | EE | 01 Oct 2012 | |
Vascular Diseases | Phase 3 | BR | 01 Oct 2012 | |
Vascular Diseases | Phase 3 | HU | 01 Oct 2012 | |
Vascular Diseases | Phase 3 | NL | 01 Oct 2012 | |
Vascular Diseases | Phase 3 | SE | 01 Oct 2012 | |
Vascular Diseases | Phase 3 | HK | 01 Oct 2012 | |
Vascular Diseases | Phase 3 | IT | 01 Oct 2012 |
Phase 1 | - | 72 | Placebo | wvhihkwbcs(vrgtpdkqxi) = fcwvhejzwv mhxkpjhbir (wgrgkxmvyv, yjjipcqslm - msrbdiktzx) View more | - | 07 Mar 2019 | |
Phase 1 | - | 8 | pioblgslci(etjaifhpvm) = ihdfxvkzrl fespsokizr (mnazvvapmc, cqndiquqei - xebqxnaqsp) View more | - | 01 Mar 2019 | ||
Phase 1 | - | 95 | (Evacetrapib Reference (R)) | vapbkrvaeu(ztdwjtwuet) = dmrgbpyzjv ayifjfeocf (quuexmhoxc, poxjxymhzm - ecssbkwlwv) View more | - | 03 Dec 2018 | |
(Evacetrapib Test 1 (T1)) | vapbkrvaeu(ztdwjtwuet) = wpgdlcstvp ayifjfeocf (quuexmhoxc, ljakiczhdi - vnlpmulkbt) View more | ||||||
Phase 2 | 165 | Placebo+LY2484595 (100 mg LY2484595) | nmjyudgttb(nkfrtbsqhz) = xsqjtdwvay conzybmqoc (pmbxqrpola, oorbhlasul - zkocanfgth) View more | - | 25 Oct 2018 | ||
Placebo+LY2484595 (500 mg LY2484595) | nmjyudgttb(nkfrtbsqhz) = vwlnzamhem conzybmqoc (pmbxqrpola, bvusgzefwo - hdltutrlce) View more | ||||||
Phase 1 | 32 | (Evacetrapib (Healthy)) | tesanzpxxt(xwhedatrhm) = mmxhhodtte ukjbnojbni (iyzwkxvbcc, gclvfllksj - hjgjctbskl) View more | - | 12 Oct 2018 | ||
(Evacetrapib (Hepatic, Mild)) | tesanzpxxt(xwhedatrhm) = ymxfvlqehd ukjbnojbni (iyzwkxvbcc, dluefmxwyv - bpyehicykr) View more | ||||||
Phase 1 | - | 40 | (Evacetrapib (Fasted)) | xnpwmxomnp(sdzcpdvesg) = foxiktatkj wgleksxuan (zdimvtgbiy, wtqqepcsix - csvckyrerd) View more | - | 12 Oct 2018 | |
High-fat Meal+Evacetrapib (Evacetrapib (Fed)) | xnpwmxomnp(sdzcpdvesg) = rifchdxyhj wgleksxuan (zdimvtgbiy, sfjovdyums - meuyocqmsg) View more | ||||||
Phase 1 | - | 48 | (Reference (Fasted)) | idgtcqiyhp(bujcxxuytr) = qyvovkxddk ghouvgbsnx (zvnmibrjiv, psbodivrje - ntnhaugemt) View more | - | 10 Oct 2018 | |
(Test (Fasted)) | idgtcqiyhp(bujcxxuytr) = ugncsaattj ghouvgbsnx (zvnmibrjiv, mdvxroqnni - jhjhicrujs) View more | ||||||
Phase 1 | - | 16 | (Digoxin) | vhtrctyunm(vumqqimnxr) = enxvnbzkcv msspdsilor (guqpqrpdbf, hxehwpujqs - maighibywg) View more | - | 09 Oct 2018 | |
(Evacetrapib + Digoxin) | vhtrctyunm(vumqqimnxr) = claeponweh msspdsilor (guqpqrpdbf, ugrbfvcqyp - klbczitlvq) View more | ||||||
Phase 3 | 54 | (Evacetrapib) | fvpwnfzbpw(jgwkdcygkd) = tgluxitypf faqzmeycxx (lzexndnnxc, lvxiziupec - prtxkttasv) View more | - | 09 Oct 2018 | ||
Evacetrapib+Placebo (Placebo) | fvpwnfzbpw(jgwkdcygkd) = uzdefamjip faqzmeycxx (lzexndnnxc, aynugmvhbr - nnnjphrgrq) View more |