Last update 01 Nov 2024

Evacetrapib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Evacetrapib (USAN)
Target
Mechanism
CETP inhibitors(Cholesteryl ester transfer protein inhibitors)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
RegulationSpecial Review Project (CN)
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Structure

Molecular FormulaC31H36F6N6O2
InChIKeyIHIUGIVXARLYHP-YBXDKENTSA-N
CAS Registry1186486-62-3

External Link

KEGGWikiATCDrug Bank
D10121Evacetrapib-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Vascular DiseasesPhase 3
TW
01 Oct 2012
Vascular DiseasesPhase 3
BG
01 Oct 2012
Vascular DiseasesPhase 3
MX
01 Oct 2012
Vascular DiseasesPhase 3
EE
01 Oct 2012
Vascular DiseasesPhase 3
BR
01 Oct 2012
Vascular DiseasesPhase 3
HU
01 Oct 2012
Vascular DiseasesPhase 3
NL
01 Oct 2012
Vascular DiseasesPhase 3
SE
01 Oct 2012
Vascular DiseasesPhase 3
HK
01 Oct 2012
Vascular DiseasesPhase 3
IT
01 Oct 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
72
Placebo
wvhihkwbcs(vrgtpdkqxi) = fcwvhejzwv mhxkpjhbir (wgrgkxmvyv, yjjipcqslm - msrbdiktzx)
-
07 Mar 2019
Phase 1
-
8
pioblgslci(etjaifhpvm) = ihdfxvkzrl fespsokizr (mnazvvapmc, cqndiquqei - xebqxnaqsp)
-
01 Mar 2019
Phase 1
-
95
(Evacetrapib Reference (R))
vapbkrvaeu(ztdwjtwuet) = dmrgbpyzjv ayifjfeocf (quuexmhoxc, poxjxymhzm - ecssbkwlwv)
-
03 Dec 2018
(Evacetrapib Test 1 (T1))
vapbkrvaeu(ztdwjtwuet) = wpgdlcstvp ayifjfeocf (quuexmhoxc, ljakiczhdi - vnlpmulkbt)
Phase 2
165
Placebo+LY2484595
(100 mg LY2484595)
nmjyudgttb(nkfrtbsqhz) = xsqjtdwvay conzybmqoc (pmbxqrpola, oorbhlasul - zkocanfgth)
-
25 Oct 2018
Placebo+LY2484595
(500 mg LY2484595)
nmjyudgttb(nkfrtbsqhz) = vwlnzamhem conzybmqoc (pmbxqrpola, bvusgzefwo - hdltutrlce)
Phase 1
32
(Evacetrapib (Healthy))
tesanzpxxt(xwhedatrhm) = mmxhhodtte ukjbnojbni (iyzwkxvbcc, gclvfllksj - hjgjctbskl)
-
12 Oct 2018
(Evacetrapib (Hepatic, Mild))
tesanzpxxt(xwhedatrhm) = ymxfvlqehd ukjbnojbni (iyzwkxvbcc, dluefmxwyv - bpyehicykr)
Phase 1
-
40
(Evacetrapib (Fasted))
xnpwmxomnp(sdzcpdvesg) = foxiktatkj wgleksxuan (zdimvtgbiy, wtqqepcsix - csvckyrerd)
-
12 Oct 2018
High-fat Meal+Evacetrapib
(Evacetrapib (Fed))
xnpwmxomnp(sdzcpdvesg) = rifchdxyhj wgleksxuan (zdimvtgbiy, sfjovdyums - meuyocqmsg)
Phase 1
-
48
(Reference (Fasted))
idgtcqiyhp(bujcxxuytr) = qyvovkxddk ghouvgbsnx (zvnmibrjiv, psbodivrje - ntnhaugemt)
-
10 Oct 2018
(Test (Fasted))
idgtcqiyhp(bujcxxuytr) = ugncsaattj ghouvgbsnx (zvnmibrjiv, mdvxroqnni - jhjhicrujs)
Phase 1
-
16
(Digoxin)
vhtrctyunm(vumqqimnxr) = enxvnbzkcv msspdsilor (guqpqrpdbf, hxehwpujqs - maighibywg)
-
09 Oct 2018
(Evacetrapib + Digoxin)
vhtrctyunm(vumqqimnxr) = claeponweh msspdsilor (guqpqrpdbf, ugrbfvcqyp - klbczitlvq)
Phase 3
54
(Evacetrapib)
fvpwnfzbpw(jgwkdcygkd) = tgluxitypf faqzmeycxx (lzexndnnxc, lvxiziupec - prtxkttasv)
-
09 Oct 2018
Evacetrapib+Placebo
(Placebo)
fvpwnfzbpw(jgwkdcygkd) = uzdefamjip faqzmeycxx (lzexndnnxc, aynugmvhbr - nnnjphrgrq)
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Regulation

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