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Last update 19 Jul 2026

Miconazole Nitrate

Last update 19 Jul 2026

Overview

R&D Status

Clinical Result

Translational Medicine

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole, 1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole, Econazole Nitrate Cream

+ [52]

Target

CYP51A1

Action

inhibitors

Mechanism

CYP51A1 inhibitors(Cytochrome P450 51 inhibitors)

Therapeutic Areas

Infectious DiseasesMouth and Tooth DiseasesUrogenital Diseases

Active Indication

Oropharyngeal candidiasisCandidiasis, OralCandidiasis+ [2]

Inactive Indication

Chronic oral candidiasisHIV InfectionsOral yeast infection

Originator Organization

Medtech SAMedtech Products, Inc.

Active Organization

Nxera Pharma Co., Ltd.

GALT Pharmaceuticals LLC

Mochida Pharmaceutical Co., Ltd.

+ [2]

Inactive Organization

Valerio Therapeutics SAMedtech Products, Inc.

License Organization

Valerio Therapeutics SA

Nxera Pharma Co., Ltd.

Vectans Pharma SA

+ [7]

Drug Highest PhaseApproved

First Approval Date

United States (30 Jan 1974),

Candidiasis, Vulvovaginal

Regulation-

Structure/Sequence

Molecular FormulaC18H15Cl4N3O4

InChIKeyMCCACAIVAXEFAL-UHFFFAOYSA-N

CAS Registry22832-87-7

Clinical Trials associated with Miconazole Nitrate

CTRI/2025/12/099508

/ Not yet recruitingPhase 1IIT

Efficacy Of Miconazole Cream Vs Clotrimazole Ear Drops In Otomycosis Management - A Randomised Control Study In A Tertiary Care Centre - nil

Start Date31 Dec 2025

Sponsor / Collaborator-

CTRI/2025/11/098228

/ Not yet recruitingPhase 2IIT

Randomized Controlled Study of an Unani Pharmacopeial Formulation versus Miconazole Cream in Quba (Tinea Corporis) - NIL

Start Date18 Dec 2025

Sponsor / Collaborator-

CTIS2025-520516-33-00

/ CompletedPhase 1

Investigation of Drug-Drug Interactions between LVDS (Levonorgestrel Vaginal Delivery System) and Miconazole in Healthy Female Participants.

Start Date28 May 2025

Sponsor / Collaborator-

100 Clinical Results associated with Miconazole Nitrate

100 Translational Medicine associated with Miconazole Nitrate

100 Patents (Medical) associated with Miconazole Nitrate

3,392

Literatures (Medical) associated with Miconazole Nitrate

01 Jun 2026·CARBOHYDRATE POLYMERS

Improving oleoyl hyaluronan self-assembly and functional properties using zinc ions

Article

Author: Sita, Jaroslav ; Židek, Ondřej ; Vacková, Monika ; Pavlík, Vojtěch ; Lehká, Kateřina ; Čepa, Martin ; Kulhánek, Jaromír ; Ondreáš, František

The self-assembly of polymer-based drug carriers plays a critical role in their performance in drug delivery and targeting. In this study, we investigated the effect of various salts on the aggregation behavior of oleoyl-modified hyaluronic acid (OL-HA) and its functional properties. Structural organization was assessed by dynamic light scattering, atomic force microscopy, scanning electron cryomicroscopy, surface tension, rheology and steady-state and time-resolved fluorescence (probes pyrene, Nile red and perylene), revealing that zinc acetate promotes self-assembly compared to water and phosphate-buffered saline, forming smaller (12 vs. 24 nm) and more compact hydrophobic domains with higher microviscosity (388 vs. 35 mPa∙s in Zn(Ac)₂ compared to PBS). These structural improvements translated into a substantial increase in drug loading capacity, with curcumin showing a 20% enhancement (50.5 vs. 42.2 μg/ml) and imidazole-based antimicrobial agents up to a 45-fold improvement (miconazole content reached 386.0 μg/ml in Zn(Ac)₂ vs. 8.3 μg/ml in PBS). Beyond loading, zinc acetate remarkably boosted the biological performance of OL-HA carriers: curcumin penetration into skin increased by 69%, antifungal-loaded systems demonstrated efficient skin permeation (reaching 43% for bifonazole), formed distinct inhibition zones against Candida albicans (zone diameter up to 5.4 ± 0.6 mm) and prevented Aspergillus brasiliensis colonization (up to 0% coverage), and zinc acetate-containing formulation achieved the greatest wound closure of 84.5 ± 10.3% in keratinocyte scratch assays. This study establishes a structure-property-function relationship for OL-HA and highlights zinc acetate as a simple yet powerful excipient for tuning the self-assembly and efficacy of HA-based nanocarriers.

01 Jun 2026·Analytical science advances

Method Development and Validation for the Simultaneous Analysis of Miconazole Nitrate, Hydrocortisone and Chlorocresol in a Pharmaceutical Topical Cream by Reverse Phase Liquid Chromatography

Article

Author: Mukaratirwa‐Muchanyereyi, Netai ; Nyoni, Stephen ; Chihiya, Pretty

ABSTRACT:

Miconazole/Hydrocortisone (HCA) cream is a pharmaceutical formulation developed as a combination of three major components (HCA, miconazole nitrate [MCN] and chlorocresol [CHL]). In some instances, reference monographs used for referencing the quantification of pharmaceutical molecules focus on individual analysis of molecules. Therefore, there is need to develop, optimize and validate methods that simultaneously separate constituents of a combined formulation. In this study, a method for the separation of HCA, MCN and CHL in miconazole/HCA cream was developed by investigating the effect of mobile phase, stationary phase, wavelength and gradient program on the separation of HCA, MCN and CHL in miconazole/HCA cream. A 10 mM ammonium acetate (AAC) buffer pH 5.0 was used. Acetonitrile was used as the organic modifier. An injection volume of 10 µL was used on a C18, 15 cm × 4.6 mm Zorbax. The optimum conditions for reverse phase liquid chromatography were obtained as follows: injection volume (10 µL), column temperature (30°C), flow rate (1 mL/min), gradient elution program: 0 min, 60AAC:40ACN; 4 min, 60AAC:40ACN; 9 min, 5AAC:95ACN; 13 min, 5AAC:95ACN using a C18 stationary phase, UV detector, 5 µm stationary phase pore size and post run of 3 min.

01 May 2026·DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Molecular identification and pathogenicity confirmation of multi-azole resistant Malassezia species isolated from dandruff infected individuals prevailing in Mysuru, India

Article

Author: S, Mahadeva Murthy ; C, Sowrabha

Worldwide distribution of dandruff associated scalp infections is caused by lipophilic Malassezia spp. This rationale lead the study to investigate the prevalence and etiologic species in a cross-sectional study involving 300 subjects who visited dermatology hospitals to seek treatment in K.R. Hospital, JSS Hospital and CSI Holdsworth Memorial Mission Hospital, Mysuru region, Karnataka, India. With the consent of participants, dandruff flakes samples were collected. The presence of Malassezia spp. were assessed by morphological and biochemical characterization, where six major yeast groups M. furfur (36%), M. globosa (21%), M. restricta (18%), M. sympodialis (12%), M. japonica (8%) and M. obtusa (5%) causing dandruff were found to be present in 79.6% of collected test samples. High resistant patterns to antimycotic data of minimal inhibitory concentration (MIC90) to Fluconazole, Ketoconazole and Miconazole indicated the emergence of multi azole resistant Malassezia spp. The isolates being pathogenic was hemolysis positive. The dandruff specific isolates M. furfur, M. restricta and M. globosa exhibited typical phospholipase activity indicating the pan-genome attributes for inducing severe itching along with scalp infections in infected individuals. It was evident from SEM data that Malassezia spp. had characteristics of yeast like structure with collarets appearing during blastospore formation. Further with M13RAPD-PCR, ITS-PCR, epidemiological specificity and genotypic relatedness of isolates to Malassezia spp. was confirmed and 18S rDNA sequences were submitted to NCBI database with the accession numbers PP189840 to PP189845. The data acquired during study can be of prime diagnostic method for timely management and accurate analysis of dandruff caused by Malassezia spp. at global settings.

News (Medical) associated with Miconazole Nitrate

14 Jan 2026

·www.prnewswire.com

TheraTears® Expands Dry Eye Portfolio with Two New Innovations: Eyelid Cleansing Wipes and Dry & Tired Preservative Free Lubricant Eye Drops

New daily solutions deliver gentle lid cleansing and all-day comfort for dry, irritated, and screen-fatigued eyes TARRYTOWN, N.Y., Jan. 14, 2026 /PRNewswire/ -- TheraTears®, the doctor-recommended dry eye therapy brand, today announced two new additions to its portfolio launching nationwide in February 2026: TheraTears® Eyelid Cleansing Wipes and TheraTears® Dry & Tired Preservative Free Lubricant Eye Drops. The innovative solutions are designed to support everyday eye comfort with gentle cleansing and dry eye relief for consumers experiencing screen-related eye fatigue. TheraTears® Eyelid Cleansing Wipes Continue Reading TheraTears® new daily solutions deliver gentle lid cleansing & all-day comfort for dry, irritated, screen-fatigued eyes Post this TheraTears® Eyelid Cleansing Wipes TheraTears® Dry & Tired Eye Preservative Free Lubricant Eye Drops Formulated for gentle everyday use, the new Eyelid Cleansing Wipes support lids and lashes as part of a daily eye care routine. Key Benefits include: Gently removes irritants that can aggravate dry eye symptoms Cleanses eyelids and lashes to support ongoing comfort Can be used daily, with a non-stinging formula Helps soothe and refresh eyes with every application Convenient, on-the-go format that's wrapped individually (do not flush) TheraTears® Dry & Tired Eye Preservative Free Lubricant Eye Drops Created for consumers experiencing dryness related to digital device use, eye strain, and long days on screens, Dry & Tired Eye lubricant eye drops offer hydrational day comfort in a preservative-free formula. Key Benefits include: Contains 2X the hydrating ingredient* Relieves dryness from screen fatigue and eye strain Provides all day soothing comfort Formulated without preservatives, making it suitable for sensitive eyes Available in convenient single-use vials *vs. TheraTears original preservative-free lubricant eye drops TheraTears® is an ophthalmologist created brand and offers a family of dry eye solutions that restore eyes' natural balance. Beginning February 2026, TheraTears® Eyelid Cleansing Wipes and TheraTears Dry & Tired Eye Therapy Lubricant Eye Drops will be available at major retailers nationwide, including Amazon, Walgreens, and Walmart. For more information, visit . About TheraTears® TheraTears®, a Prestige Consumer Healthcare brand, is a pioneer in dry eye relief, founded by Dr. Jeffrey P. Gilbard, M.D., a Harvard-trained ophthalmologist, and innovator in ocular health. TheraTears® offers science-backed solutions and contains a proprietary blend of OxyLytes™, the five vital electrolytes (Sodium Na+, Potassium K+, Calcium Ca2+, Magnesium Mg2+, Bicarbonate HCO3-) found in natural tears. The EXTRA formula offers up to 12 hours of hydrating comfort. Available over the counter in Dry Eye Therapy, EXTRA Dry Eye Therapy, Preservative Free vials, and Liquid Gel Nighttime Therapy formats, TheraTears® is trusted by persistent dry eye sufferers worldwide. Learn more at . About Prestige Consumer Healthcare Inc. Prestige Consumer Healthcare is a leading consumer healthcare products company with sales throughout the U.S. and Canada, Australia, and in certain other international markets. The Company's diverse portfolio of brands include Monistat® and Summer's Eve® women's health products, BC® and Goody's® pain relievers, Clear Eyes® and TheraTears® eye care products, DenTek® specialty oral care products, Dramamine® motion sickness treatments, Fleet® enemas and glycerin suppositories, Chloraseptic® and Luden's® sore throat treatments and drops, Compound W® wart treatments, Little Remedies® pediatric over-the-counter products, Boudreaux's Butt Paste® diaper rash ointments, Nix® lice treatment, Debrox® earwax remover, Gaviscon® antacid in Canada, and Hydralyte® rehydration products and the Fess® line of nasal and sinus care products in Australia. Visit the Company's website at . SOURCE TheraTears® 21% more press release views with Request a Demo

03 Dec 2025

·www.prnewswire.com

Amid Rising Screen Time and Lifestyle Stress, New Survey Reveals 3 in 4 Americans Battle Dry Eye Symptoms Weekly

80% of Participants Open to Science-Backed Relief that Mimics Natural Tears; TheraTears® Represents a Solution for Lasting Eye Comfort TARRYTOWN, N.Y., Dec. 3, 2025 /PRNewswire/ -- A new national survey commissioned by TheraTears®, a leading provider of over-the-counter (OTC) eye drops, uncovers the pervasive impact of dry eye symptoms on Americans' daily lives. Conducted by OnePoll in October 2025 among 1,000 U.S. adults experiencing dry eye, the findings show that dry eye is far from a minor irritation—it's a persistent challenge worsened by modern factors like excessive screen time, seasonal changes, and sleep deprivation. Continue Reading TheraTears® Understanding Dry Eye Infographic The survey highlights a strong consumer demand for innovative solutions: 80% of respondents with dry eye symptoms indicated they would try a science-backed eye drop that mimics natural tears and restores tear-film balance. This aligns directly with TheraTears®' unique formulation, which contains OxyLytes™, the five vital electrolytes found in natural tears and provides immediate, long-lasting relief. Key insights from the survey include: Daily Struggle: 76% of sufferers experience symptoms daily or multiple times per week, with an average discomfort rating of 6.1 out of 10. Nearly half rated their discomfort at 5 or higher, and 1 in 10 reported severe levels of 8 or more. Worsening Trends: 34% noted their symptoms have worsened over the past year, compared to just 8% who saw improvement, pointing to an escalating wellness concern. Knowledge Gap: Almost two-thirds were unaware that dry eye stems from a salt imbalance in the tear film, creating an opportunity for education on science-driven relief. Common Triggers: Screen time tops the list at 70%, followed by weather shifts (50%), allergies (45%), and lack of sleep (30%). Quality-of-Life Effects: Respondents reported reduced focus, red eyes, and eye strain, impacting productivity, confidence, and overall well-being. Treatment Habits: While 66% rely on OTC drops, 48% have never checked the ingredients, underscoring the potential for upgrades to doctor-designed options like TheraTears®. "Modern life takes a toll on our eyes, from endless hours in front of screens to fluctuating weather patterns," said Dr. Elise Kramer, OD, a renowned optometrist. Not all eye drops are the same. TheraTears® rebalances the tear film at the source, providing clinically proven hydration and long-lasting comfort that restores natural balance." TheraTears® encourages those experiencing dry eye to explore its range of products, available at major retailers or online. About TheraTears® TheraTears®, a Prestige Consumer Healthcare brand, is a pioneer in dry eye relief, founded by Dr. Jeffrey P. Gilbard, M.D., a Harvard-trained ophthalmologist, and innovator in ocular health. TheraTears® offers science-backed solutions and contains a proprietary blend of OxyLytes™, the five vital electrolytes (Sodium Na+, Potassium K+, Calcium Ca2+, Magnesium Mg2+, Bicarbonate HCO3-) found in natural tears. The EXTRA formula offers up to 12 hours of hydrating comfort. Available over the counter in Dry Eye Therapy, EXTRA Dry Eye Therapy, Preservative Free vials, and Liquid Gel Nighttime Therapy formats, TheraTears® is trusted by persistent dry eye sufferers worldwide. Learn more at . About Prestige Consumer Healthcare Inc. Prestige Consumer Healthcare is a leading consumer healthcare products company with sales throughout the U.S. and Canada, Australia, and in certain other international markets. The Company's diverse portfolio of brands include Monistat® and Summer's Eve® women's health products, BC® and Goody's® pain relievers, Clear Eyes® and TheraTears® eye care products, DenTek® specialty oral care products, Dramamine® motion sickness treatments, Fleet® enemas and glycerin suppositories, Chloraseptic® and Luden's® sore throat treatments and drops, Compound W® wart treatments, Little Remedies® pediatric over-the-counter products, Boudreaux's Butt Paste® diaper rash ointments, Nix® lice treatment, Debrox® earwax remover, Gaviscon® antacid in Canada, and Hydralyte® rehydration products and the Fess® line of nasal and sinus care products in Australia. Visit the Company's website at . SOURCE TheraTears® 21% more press release views with Request a Demo

Clinical Result

23 Aug 2024

·pharma.economictimes.indiatimes.com

Govt bans 156 medicines including antibiotics, painkillers, multivitamins: Here is the full list

New Delhi: In a significant move aimed at safeguarding public health, the Indian government has banned 156 fixed-dose combination (FDC) drugs, including a variety of antibiotics, painkillers, multivitamins, and medications for treating fever and hypertension. This decision marks the largest crackdown on FDCs since 2016, when 344 such drugs were prohibited. The Union Ministry of Health and Family Welfare issued a gazette notification on Thursday, officially prohibiting the manufacture, sale, and distribution of the banned FDCs. The ban was based on the recommendations of an expert panel that reviewed a total of 324 FDCs. Impact on Pharmaceutical Industry The banned FDCs include popular combinations such as mefenamic acid and paracetamol injections, commonly used for pain relief and fever, and omeprazole magnesium with dicyclomine HCl, used to treat abdominal pain. The ban is expected to impact major pharmaceutical companies, including Sun Pharmaceuticals, Cipla, Dr. Reddy's Laboratories, Torrent Pharmaceuticals, and Alkem Laboratories. Fixed Dose Combinations Drug Banned List Here is a table listing all 156 banned Fixed Dose Combinations (FDCs) SN Fixed Dose Combination (FDC) 1 Amylase + Protease + Glucoamylase + Pectinase + Alpha Galactosidase + Lactase + Beta-Gluconase + Cellulase + Lipase + Bromelain + Xylanase + Hemicellulase + Malt diastase + Invertase + Papain 2 Antimony Potassium Tartrate + Dried Ferrous Sulphate 3 Benfotiamine + Silymarin + L-Ornithine L-aspartate + Sodium Selenite + Folic acid + Pyridoxine hydrochloride 4 Bismuth Ammonium Citrate + Papain 5 Cyproheptadine HCl + Thiamine HCl + Riboflavine + Pyridoxine HCl + Niacinamide 6 Cyproheptadine Hydrochloride + Tricholine Citrate + Thiamine Hydrochloride + Riboflavine + Pyridoxine Hydrochloride 7 Rabeprazole Sodium (As enteric coated tablet) + Clidinium Bromide + Dicyclomine HCl + Chlordiazepoxide 8 Fungal Diastase + Papain + Nux vomica Tincture + Cardamom Tincture + Casein Hydrolysed + Alcohol 9 Mefenamic Acid + Paracetamol Injection 10 Omeprazole Magnesium + Dicyclomine HCl 11 S-adenosyl methionine + Metadoxine + Ursodeoxycholicacid BP + L-Methylfolate Calcium eq. to L- Methylfolate + Choline bitartratee + Silymarin + L-ornithine Laspartate + Inositol + Taurine 12 Silymarin + Thiamine Mononitrate + Riboflavin + Pyridoxine HCl + Niacinamide + Calcium pantothenate + Vitamin B12 13 Silymarin + Pyridoxine HCl + Cyanocobalamin + Niacinamide + Folic Acid 14 Silymarin + Vitamin B6 + Vitamin B12 + Niacinamide + Folic acid + Tricholine Citrate 15 Sodium Citrate + Citric Acid Monohydrate Flavored with Cardamom Oil, Caraway Oil, Cinnamon Oil, Clove Oil, Ginger Oil + Alcohol 16 Sucralfate + Acelofenac 17 Sucralfate + Domperidone + Dimethicone 18 Sucralfate + Domperidone 19 Tincture Ipecacuanha + Tincture Urgenia + Camphorated Opium Tincture + Aromatic Spirit of Ammonia + Chloroform + Alcohol 20 Ursodeoxycholic Acid + Metformin HCl 21 Weak Ginger tincture + Aromatic Spirit of Ammonia + Peppermint Spirit + Chloroform + Sodium Bicarbonate + Compound Cardamom + Alcohol 22 Sucralfate + Pantoprazole Sodium + Zinc Gluconate + Light Magnesium Carbonate 23 Aloe + Vitamin E Soap 24 Povidone Iodine+ Metronidazole + Aloe 25 Azelaic acid + Tea Tree Oil + Salicylic acid + Allantoin + Zinc oxide + Aloe vera + Jojoba oil + Vitamin E + Soap noodles 26 Azithromycin + Adapalene 27 Calamine + Aloes + Allantoin 28 Calamine + Diphenhydramine Hydrochloride + Aloe + Glycerine + Camphor 29 Chlorphenesin + Zinc oxide + Starch 30 Clindamycin Phosphate + Zinc acetate 31 Gamma Benzene Hexachloride + Benzocaine 32 Glucosamine hydrochloride + Diacerein + Menthol + Camphor + Capsaicin 33 Hydroxyquinone 2.0%w/w + Octyl Methoxycinnamate 5.0% w/w + Oxybenzone 30 % w/w 34 Ketoconazole +Zinc Pyrithione +D-Panthenol +Tea Tree Oil +Aloes 35 Ketoconazole +Aloe vera+ Vitamin A Acetate 36 Ketoconazole +Aloes + ZPTO 37 Kojic Acid +Arbutin +Octinoxate +Vitamin E + Mulberry 38 Lornoxicam +capsaicin +menthol+ camphor 39 Lornoxicam + Thiocolchicoside +Oleum Lini +Menthol + Methyl salicylate 40 Menthol + Aloe vera Topical Spray 41 Menthol +Lignocaine HCl +Aloe vera gel +Clotrimazole +Diphenhydramine 42 Miconazole nitrate + Gentamicin + Fluocinolone Acetonide +Zinc Sulphate 43 Miconazole +Tinidazole 44 Minoxidil +Aminexil+ Alcohol 45 Minoxidil +Azelaic acid + saw palmetto 46 Minoxidil +Aminexil 47 Pine Bark extract+ Kojic acid +Sodium Ascorbyl Phosphate 48 Povidone Iodine +Tinidazole +Zinc sulphate 49 Povidone Iodine + Ornidazole + Dexpanthenol 50 Salicyclic acid +Aloe vera+ Allantoin +D-Panthenol 51 Silver sulphadiazine +Chlorhexidine Gluconate solution +Allantoin + Aloe vera gel +Vitamin E acetate 52 Sodium salicylate + Zinc gluconate + Pyridoxine HCl 53 Tetracycline + Colistin Sulphate 54 Clomiphene +Ubidecarenone 55 Combikit of Clomiphene Citrate + Estradiol Valerate 56 Flavoxate HCl +Ofloxacin 57 Clomiphene Citrate +N-Acetylcysteine 58 Primerose Oil +Cod liver oil 59 Sildenafil Citrate +Papaverine +L-Arginine 60 Tranexamic acid +Mefenamic acid + Vitamin K1 61 Divalproex Sodium +Oxcarbazepine 62 Divalproex Sodium + Levetiracitam 63 Ergotamine tartrate +Caffeine + Paracetamol +Prochlorperazine maleate 64 Piracetam + Ginkgo biloba extracts + Vinpocetin 65 Ginkgo biloba + methylcobalamin 66 Ginkgo biloba + methylcobalamin + Alpha lipoic acid +Pyridoxine HCl 67 Ginseng Extract +Dried extract of Ginkgo Biloba 68 Meclizine HCl+ Paracetamol + Caffeine 69 Nicergoline + Vinpocetine 70 Gamma Linolenic Acid + Methylcobalamin 71 Beclomethasone Dipropionate + Neomycin Sulphate + Clotrimazole + Lignocaine HCl 72 Boric acid+ Phenylephrine HCl + Naphazoline Nitrate + Menthol + Camphor 73 Naphazoline HCl + Chlorpheniramine Maleate + Zinc Sulphate + Hydroxy Propyl Methyl Cellulose 74 Chlorpheniramine Maleate + Naphazoline HCl + Zinc Sulphate + Sodium Chloride + Hydroxy Propyl Methyl Cellulose 75 Chlorpheniramine Maleate + Naphazoline HCl + Hydroxy Propyl Methyl Cellulose 76 Chlorpheniramine Maleate + Sodium Chloride + Boric Acid + Tetrahydrozoline HCl 77 Chlorpheniramine Maleate + Phenylephrine HCl + Antipyrine 78 Ketorolac Tromethamine + Chlorpheniramine Maleate + Phenylephrine HCl + Hydroxy Propyl Methyl Cellulose 79 Ketorolac Tromethamine + Flurometholone 80 Naphazoline HCl + Zinc Sulphate + Boric Acid + Sodium Chloride+ Chlorpheniramine Maleate 81 Naphazoline HCl + Hydroxy Propyl Methyl Cellulose + Boric Acid + Borax + Menthol + Camphor 82 Naphazoline HCl + Hydroxy Propyl Methyl Cellulose + Chlorpheniramine Maleate SN Fixed Dose Combination (FDC) 83 Diphenhydramine Hydrochloride + Phenylephrine Hydrochloride + Menthol + Camphor 84 Diphenhydramine Hydrochloride + Phenylephrine Hydrochloride + Sodium Chloride + Hydroxy Propyl Methyl Cellulose 85 Diphenhydramine Hydrochloride + Phenylephrine Hydrochloride + Sodium Chloride + Methylparaben 86 Methenamine + Sodium Benzoate + Benzyl Alcohol 87 Paracetamol + Phenylephrine Hydrochloride + Chlorpheniramine Maleate 88 Paracetamol + Phenylephrine Hydrochloride + Chlorpheniramine Maleate + Caffeine 89 Propoxyphene + Chlorpheniramine Maleate 90 Propoxyphene + Phenylephrine Hydrochloride + Chlorpheniramine Maleate 91 Propoxyphene + Diphenhydramine Hydrochloride + Phenylephrine Hydrochloride 92 Sodium Benzoate + Sodium Citrate + Citric Acid 93 Vitamin A Palmitate + Vitamin C + Vitamin E + Vitamin B6 + Vitamin B12 94 Vitamin A Palmitate + Vitamin C + Vitamin E + Niacinamide 95 Vitamin B6 + Vitamin B12 + Vitamin C 96 Vitamin B6 + Vitamin B12 + Niacinamide 97 Vitamin B12 + Vitamin B6 + Vitamin C + Folic Acid 98 Vitamin B12 + Vitamin B6 + Niacinamide + Folic Acid 99 Vitamin C + Vitamin E + Vitamin A + Niacinamide 100 Vitamin D + Calcium + Magnesium 101 Vitamin D + Calcium + Magnesium + Zinc 102 Calcium + Vitamin D + Vitamin K 103 Calcium + Vitamin D + Magnesium + Zinc 104 Calcium + Vitamin D + Vitamin K + Magnesium 105 Calcium + Vitamin D + Vitamin K + Magnesium + Zinc 106 Vitamin E + Vitamin A + Vitamin C + Niacinamide 107 Vitamin E + Vitamin A + Vitamin C + Folic Acid 108 Vitamin E + Vitamin A + Vitamin C + Biotin 109 Vitamin E + Vitamin A + Vitamin C + Vitamin B12 110 Vitamin E + Vitamin C + Folic Acid 111 Vitamin E + Vitamin C + Biotin 112 Vitamin E + Vitamin C + Vitamin B12 113 Vitamin E + Vitamin C + Zinc 114 Calcium + Vitamin D + Omega-3 Fatty Acids 115 Calcium + Vitamin D + Omega-3 Fatty Acids + Vitamin K 116 Calcium + Vitamin D + Omega-3 Fatty Acids + Vitamin K + Magnesium 117 Calcium + Vitamin D + Omega-3 Fatty Acids + Vitamin K + Zinc 118 Vitamin A + Vitamin C + Vitamin E + Beta-Carotene 119 Vitamin A + Vitamin C + Vitamin E + Beta-Carotene + Zinc 120 Vitamin C + Vitamin E + Beta-Carotene 121 Vitamin C + Vitamin E + Beta-Carotene + Zinc 122 Vitamin C + Vitamin E + Selenium 123 Vitamin D + Calcium + Vitamin K + Omega-3 Fatty Acids 124 Vitamin D + Calcium + Vitamin K + Omega-3 Fatty Acids + Magnesium 125 Vitamin D + Calcium + Vitamin K + Omega-3 Fatty Acids + Zinc 126 Vitamin D + Calcium + Vitamin K + Omega-3 Fatty Acids + Biotin 127 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Selenium 128 Vitamin E + Vitamin A + Vitamin C + Zinc 129 Vitamin E + Vitamin A + Vitamin C + Selenium 130 Vitamin E + Vitamin A + Vitamin C + Biotin 131 Vitamin E + Vitamin A + Vitamin C + Folic Acid + Niacinamide 132 Vitamin E + Vitamin C + Beta-Carotene + Zinc 133 Vitamin C + Vitamin E + Biotin + Folic Acid 134 Vitamin C + Vitamin E + Beta-Carotene + Folic Acid 135 Vitamin C + Vitamin E + Beta-Carotene + Selenium 136 Vitamin E + Vitamin C + Beta-Carotene + Biotin 137 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Biotin 138 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Selenium 139 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Vitamin B12 140 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Vitamin B6 141 Vitamin D + Calcium + Omega-3 Fatty Acids + Vitamin K + Folate 142 Calcium + Vitamin D + Magnesium + Vitamin K + Omega-3 Fatty Acids 143 Calcium + Vitamin D + Magnesium + Vitamin K + Biotin 144 Calcium + Vitamin D + Magnesium + Vitamin K + Selenium 145 Calcium + Vitamin D + Magnesium + Vitamin K + Vitamin B12 146 Calcium + Vitamin D + Magnesium + Vitamin K + Folate 147 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Vitamin B6 148 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Vitamin B12 149 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Folic Acid 150 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Biotin 151 Calcium + Vitamin D + Vitamin K + Omega-3 Fatty Acids + Selenium 152 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids 153 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids + Zinc 154 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids + Biotin 155 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids + Selenium 156 Vitamin A + Vitamin C + Vitamin E + Omega-3 Fatty Acids + Vitamin B12

Drug Approval

100 Deals associated with Miconazole Nitrate

External Link

KEGG	Wiki	ATC	Drug Bank
D00882	Miconazole Nitrate	D01AC02 A07AC01 S02AA13	DB01110

R&D Status

Approved

10 top approved records.

to view more data

Indication	Country/Location	Organization	Date
Oropharyngeal candidiasis	United States	GALT Pharmaceuticals LLC	16 Apr 2010
Candidiasis, Oral	Japan	Mochida Pharmaceutical Co., Ltd.	19 Jan 1993
Candidiasis	China	Jiangsu Farever Pharmaceutical Co., Ltd.	01 Jan 1985
Mycoses	China	Jiangsu Farever Pharmaceutical Co., Ltd.	01 Jan 1985
Candidiasis, Vulvovaginal	United States	Medtech Products, Inc.	30 Jan 1974

Developing

10 top R&D records.

to view more data

Indication	Highest Phase	Country/Location	Organization	Date
Chronic oral candidiasis	Phase 3	China	Valerio Therapeutics SA	16 Oct 2013
Oral yeast infection	Phase 3	China	Valerio Therapeutics SA	16 Oct 2013
HIV Infections	Phase 3	United States	Valerio Therapeutics SA	01 Jul 2006
HIV Infections	Phase 3	Canada	Valerio Therapeutics SA	01 Jul 2006

Clinical Result

Indication

Phase

Evaluation

View All Results

Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


NCT05660382 (CTgov)	Phase 3	Otomycosis	112	Miconazole (2%) oil and mineral oil (Active Group)	kkkerxfnbp = uqapurcabz rinvgndyel (wtyrpnfysb, ruvigvvewe - envjngizpn) View more	-	20 Apr 2026
				Placebo (Placebo Group)	kkkerxfnbp = rbkzmjguik rinvgndyel (wtyrpnfysb, hrbhtnquns - pevvqetksz) View more
NCT04432376 (CTgov)	Phase 2/3	Otomycosis	382	miconazole 2% oil (Active Treatment Arm)	avjuaxylgp = qkholmbkfr lmngaifqvg (bjiffsvlpl, tqtrrccklc - kjnfuqonmf) View more	-	04 Nov 2022
				vehicle oil (Placebo Treatment Arm)	avjuaxylgp = nqthdhscig lmngaifqvg (bjiffsvlpl, shfukziayt - yaheeqrpkn) View more
NCT03130738 (CTgov)	Phase 2	Otomycosis	65	7-Day Miconazole Oil (Miconazole 2%) (7-Day Miconazole Oil (Miconazole 2%))	kjgnrazrlu = bqcbsssetg hwiiilxyea (algdcepljb, hmdquqieou - nwzmupdbzh) View more	-	08 May 2020
				14-Day Miconazole Oil (Miconazole 2%) (14-Day Miconazole Oil (Miconazole 2%))	kjgnrazrlu = ilgwmlqgws hwiiilxyea (algdcepljb, cikkskhfgq - dqruxdkzdg) View more
NCT00702507 (Pubmed \| Pediatr Dermatol)	Phase 4	Diaper Rash	-	0.25% Miconazole Nitrate Ointment	eyrhnfhpfp(fntpbrhhxz) = ludmmhplzx pkxiopodnd (vxmnpblvmq ) View more	Positive	01 Nov 2013
NCT00390780 (CTgov)	Phase 3	Oropharyngeal candidiasis \| HIV Infections	578	Miconazole Lauriad (Miconazole Lauriad Buccal Tablet)	cwgpjtbijv = gffojovwlm vumoehynub (qctgblwvra, kydepgvuoh - ekczvopsgx) View more	-	29 Aug 2013
				Clotrimazole (Clotrimazole Troches)	cwgpjtbijv = iabyijmigf vumoehynub (qctgblwvra, sihaoaovkj - sgsvobsenp) View more
NCT01769339 (CTgov)	Phase 4	Candidiasis, Vulvovaginal	115	Hydrocortisone+Miconazole	szjpopoapr(ztbdqfmjkw) = jvbwgvjsmo qxrqnnwjgt (eqztfwrmji, 1.41) View more	-	25 Mar 2013
NCT00702507 (CTgov)	Phase 4	Candidiasis, Cutaneous \| Diaper Rash	200	Vusion+miconazole nitrate (Vusion Treatment)	airtcrszrb = qpehvrfxwo peuqnvghaq (izsgkrtdvh, qmlxkeynvg - fniwtomdkf) View more	-	07 Oct 2011
				miconazole nitrate (Vusion Initial Treatment Phase)	okbwgbttis(bphcxadole) = cddeibvpyk hpmfbavycm (sccasmvkou, yzidiarqsl - npliqupyxd) View more

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