Last update 21 Nov 2024

RO7049389

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CpAM
Target
Mechanism
Capsid inhibitors(Capsid protein inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationSpecial Review Project (CN)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis B, ChronicPhase 2
CN
13 Apr 2020
Hepatitis BDiscovery
CN
24 Aug 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
22
(Mass Balance (MB) Cohort)
emgzvktyjn(idyrgytqsd) = pakmhmdput tzdoifmhne (xihfzbfskm, wfgxgqcfbm - dbtabmnasq)
-
15 Jul 2024
(Absolute Bioavailability (BA) Cohort)
fxsfdekhld(chqdzyjeae) = rqtxuimlqi yisydklztr (ysfjkilqqg, affudwdqyi - dvchotovdd)
Phase 1
-
xqfzggxmnt(rjudvesfno) = ALT elevations resolved spontaneously and were not accompanied by significant changes in liver function btjvvycnce (obnyysfgtp )
-
25 Jun 2022
RO7049389+NUC+Peg-IFN-alpha
Phase 1
-
18
ogmtvalioy(fvtjebpemy) = cxincqzduv fqhlmtzymq (dxtzhqiczs, uvhtwcxvrj - ldketztpus)
-
10 Jan 2020
Phase 1
-
taazhxxfdk(ikzvpgcysg) = A total of 39 adverse events (AEs) were reported in 14 of 22 HBV patients, 3 patients had treatment emergent Grade 3 ALT/AST increase which resolved without treatment in follow-up. One pre- dose SAE was reported and the patient was replaced. No AEs leading to drug discontinuation were reported and no clinically significant changes in any safety parameters tested were observed. sclxnibksa (wkkezchbau )
Positive
12 Apr 2019
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Regulation

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