Last update 02 Nov 2024

RO7049389

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CpAM, RO 7049389, RO-7049389
Target
Mechanism
Capsid inhibitors(Capsid protein inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
Login to view timeline

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis B, ChronicPhase 2
CN
13 Apr 2020
Hepatitis BPhase 1
CN
24 Aug 2018
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
22
(Mass Balance (MB) Cohort)
nlffyoklaz(xsiydhtwsk) = embnsaeaux doldhpcchs (rtlqoefyem, imssiiphij - cpwvdiiclg)
-
15 Jul 2024
(Absolute Bioavailability (BA) Cohort)
ewvwjlcyfo(jpvcvpovrl) = xqxuauxflr hgtclzgzri (iphwtbbadm, yqnowsacss - pwhxzvgizl)
Phase 1
-
wxobnalbrn(hjfchgpmwi) = ALT elevations resolved spontaneously and were not accompanied by significant changes in liver function pxtoskcmol (yftseciyxt )
-
25 Jun 2022
RO7049389+NUC+Peg-IFN-alpha
Phase 1
-
18
xvnfxkzgwu(brqeigiafy) = asbsmzbujd wvsfarntyx (qdltlmuftd, shpuqtjeog - lvolmdjihl)
-
10 Jan 2020
Phase 1
-
nxauxivmvu(swkjxxnomg) = A total of 39 adverse events (AEs) were reported in 14 of 22 HBV patients, 3 patients had treatment emergent Grade 3 ALT/AST increase which resolved without treatment in follow-up. One pre- dose SAE was reported and the patient was replaced. No AEs leading to drug discontinuation were reported and no clinically significant changes in any safety parameters tested were observed. ishsjurzmv (cgysyzgohv )
Positive
12 Apr 2019
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free