A Clinical study to evaluate the Safety and efficacy of hyaluronic acid injection containing stromal vascular fraction extracted from adipose tissue of patients with enophthalmos

Start Date31 Jan 2025

Sponsor / Collaborator

Bundang CHA Hospital

CTRI/2024/11/077456

/ Not yet recruitingNot ApplicableIIT

Effectiveness of 0.1 percent Hyaluronic Acid with 0.2 percent Chlorhexidine Mouthrinse or 0.2 percent Chlorhexidine Mouthrinse alone as adjunct to scaling and root planing on clinical parameters and salivary aspartate aminotransferase marker in Periodontitis : A Prospective randomized observer blinded study - NIL

Start Date10 Dec 2024

Sponsor / Collaborator

Dr. Reddy's Laboratories Ltd.

NCT06310941

/ Not yet recruitingNot ApplicableIIT

Aspiration of Bronchial Secretions With Mechanical Insufflation-Exsufflation and Hypertonic Saline in Bacterial Nosocomial Tracheobronchitis and Pneumonia in Intubated Patients.

Multicenter, randomized open label clinical trial to evaluate IEM and HS as concomitant therapy for respiratory tract infection in patients under artificial ventilation in the ICU.
Lung infection is a serious complication that may occur during hospital stay and may need artificial respiration or even develop during artificial ventilation for other causes.
Current specific treatment consists of intravenous antibiotics. The current study evaluated whether aspiration and drainage of infected sputum helps curing this severe complication and whether nebulized HS has additional benefits, like eradicating bacteria or reducing inflammation.

Start Date01 Dec 2024

Sponsor / Collaborator

Hospital San Carlos, Madrid

100 Clinical Results associated with Hyaluronic acid

100 Translational Medicine associated with Hyaluronic acid

100 Patents (Medical) associated with Hyaluronic acid

1,222

Literatures (Medical) associated with Hyaluronic acid

01 Apr 2025·International Journal of Biological Macromolecules

Emerging roles of hyaluronic acid hydrogels in cancer treatment and wound healing: A review

Article

Author: Wu, Gang ; Tian, Xiaohui ; Zha, Lisha ; Zhong, Chunyan ; Hou, Lingmi ; Feng, Xiaoqiang

Hyaluronic acid (HA)-derived hydrogels signify a noticeable development in biomedical uses, especially in cancer treatment and wound repair. Cancer continues to be one of the foremost causes of death globally, with current therapies frequently impeded by lack of specificity, serious side effects, and the emergence of resistance. HA hydrogels, characterized by their distinctive three-dimensional structure, hydrophilic nature, and biocompatibility, create an advanced platform for precise drug delivery, improving therapeutic results while minimizing systemic toxicity. These hydrogels facilitate the regulated release of medications, genes, and various therapeutic substances, enhancing the effectiveness of chemotherapy, radiotherapy, and immunotherapy. Additionally, they can be designed to react to stimuli like pH, light, and magnetic fields, enhancing their therapeutic capabilities. In the process of wound healing, the hydrophilic and porous characteristics of HA hydrogels establish a moist setting that encourages cell growth and aids in tissue restoration. By imitating the extracellular matrix, they promote tissue regeneration, improve angiogenesis, and influence immune reactions. This review examines the various functions of HA-based hydrogels in cancer treatment and wound healing, highlighting their advancement, uses, and ability to change existing therapeutic methods in these important health sectors.

01 Apr 2025·International Journal of Biological Macromolecules

Emerging trends in designing polysaccharide based mucoadhesive network hydrogels as versatile platforms for innovative delivery of therapeutic agents: A review

Review

Author: Kumari, Ankita ; Singh, Baljit

INTRODUCTIONThe rapid progress in polymer science has designed innovative materials for biomedical applications. In the case of drug design, for each new therapeutic agent, a drug delivery system (DDS) is required to improve its pharmacokinetic and pharmacodynamic parameters. Therefore, significant research has been carried out to develop drug delivery (DD) carriers for these new therapeutic agents. Hydrogels have been explored as potential candidates to prepare controlled drug delivery (CDD) systems to address the challenges related to the performance of the conventional DD formulations. Mucoadhesive drug delivery system (MUCO-DDS) is a specialized form of CDD system, facilitating site-specific DD, protecting the drug from first pass metabolism and enhancing its overall bioavailability.METHODSThe present article provides a comprehensive discussion of the synthesis, properties and applications of polysaccharide-derived MUCO-DDS. Different natural polymer-derived MUCO-DDS including chitosan, alginate, pectin, xanthan gum, psyllium, gelatin, cellulose, hyaluronic acid, guar gum, sterculia gum and tragacanth gum have been reported. Herein, these DDS were elaborately discussed along with their applications and future-prospective. These DDS are classified on the basis of drug administration (nasal, ocular, vagina/rectal & buccal DDS) and drug distribution (reservoir and monolithic polymer matrix). Factors contributing to modifications of properties of MUCO-DDS were also demonstrated along with different stages and theories of mucoadhesion.RESULTSPolysaccharides exhibit properties such as biocompatibility, biodegradability, and flexibility, making them ideal for CDD applications. MUCO-DDS demonstrates several significant advantages. Moreover, the article bridges theoretical insights with practical applications and future research prospects, ensuring its relevance for advancements in the concerned field. This review serves as a comprehensive resource, addressing gaps in previous literature and paving the way for innovations in MUCO-DDS, through a comparative analysis of the advantages, limitations, and modifications of natural polymers.CONCLUSIONSIn conclusion, this review gives an overview of the current developments in the field of mucoadhesive DD systems and also gives insights into the future perspectives. The MUCOAD of DDS could be modulated by the inclusion of various natural and synthetic components in hydrogels. Future directions for the researchers are underway to integrate nanotechnology with mucoadhesive systems to create hybrid platforms. Overall, by addressing current limitations and leveraging emerging technologies, these systems can revolutionize drug delivery for a wide range of therapeutic applications.

01 Mar 2025·Journal of Craniofacial Surgery

Application of Hyaluronic Acid Linear Stereoscopic Stack Volume Enhancement Injection Technique in Nasal Reshaping

Article

Author: Lei, Jiaqi ; Liu, Qingyang ; Dong, Ruiping

Hyaluronic acid (HA) injection, traditionally used for non-surgical rhinoplasty, is often associated with adverse effects such as increased nasal dorsum width. This study introduces the linear stereoscopic stack volume enhancement (LSSVE) injection technique as a solution for patients with low-profile noses, aiming to improve the nasal dorsum dimension, prevent long-term nasal widening, and address related concerns. A retrospective analysis was conducted on the clinical registry data of patients treated at Shanghai Phiskin Clinic from December 2020 to June 2024, who received HA injections using the LSSVE technique. Each rhinoplasty patient received a personalized injection, with doses ranging from 0.59 to 1.03 mL, adjusted based on specific characteristics of their nose and forehead. The procedure utilized a 25G blunt cannula to administer HA between the nasal bone periosteum and fascial layer using the LSSVE technique. The primary endpoint was patient improvement assessed 6 months post-injection using the Global Aesthetic Improvement Scale (GAIS), evaluated by a blinded assessor. In addition, patient satisfaction and complications were assessed. A total of 189 patients (181 females and 28 males) were included in the study, all of whom received a single HA LSSVE injection. Six months post-injection, the GAIS improvement rate was 82.83%, with a patient satisfaction rate of 84.83%. The injection effect was maintained for 6 months without any nasal dorsum widening, and a significant increase in the nasofrontal angle was observed (P<0.001). No long-term complications were reported post-injection. The LSSVE injection technique demonstrated effectiveness in overcoming the limitations of traditional HA rhinoplasty and preventing long-term nasal dorsum widening.

News (Medical) associated with Hyaluronic acid

01 Aug 2024

·www.prnewswire.com

Sirnaomics Announces a Partnership with Gore Range Capital for Establishment of a JV, Sagesse Bio, to Advance Its RNAi Therapeutics into Aesthetic Medicine

HONG KONG, GERMANTOWN, Md. and SUZHOU, China, July 31, 2024 /PRNewswire/ -- Sirnaomics Ltd. (the " Company", Stock Code: 2257.HK, together with its subsidiaries, the " Group" or " Sirnaomics"), a leading biopharmaceutical company engaging in discovery and development of advanced RNAi therapeutics, today announced a partnership with Gore Range Capital LLC (" Gore Range Capital") (Dallas, TX, USA) for establishment of a joint venture, Sagesse Bio, Inc., to advance its novel RNAi therapeutic products into aesthetic medicine. Sagesse Bio, Inc., a Delaware corporation (" Sagesse Bio"), combines the strength of Sirnaomics' leadership in RNAi-based technology and product development for focal fat reduction and Gore Range Capital's world leading expertise in skin health industry and financial resources, to accelerate clinical development of the company's innovative products for addressing a fast-growing aesthetic medicine market. Sagesse Bio will rapidly advance Sirnaomics lead compound that is IND-enabled and currently in Phase II clinical trials for other indications. Initial indications of interest include body contouring and fat reduction. The founders, board of directors, and newly established executive management team of Sagesse Bio are comprised of a group of well-accomplished senior executives from skin health industry, world-renowned clinicians in dermatology and aesthetic medicine, and leading experts in RNAi medicine. The strategic goal of Sagesse Bio is to become a world-leading aesthetic medicine company with innovative technologies and aesthetic products. Frederick Beddingfield, MD, PhD, serving as Chairperson of the board of directors of Sagesse Bio, is an internationally renowned dermatologist and expert in biopharma and the aesthetics industry, who has led the development of global leading brands such as BOTOX®, JUVEDERM®, LATISSE® and KYBELLA®. He served as Chief Medical Officer of Allergan Medical and Kythera, and as CEO of Sienna Bio and Kira Pharmaceuticals, and currently serves on the board of directors of Cytrellis Biosystems. Dr. Beddingfield stated: "I could not be more excited to help lead and build Sagesse Bio. We have an amazing team with the right experience and a unique opportunity based on the finding of adipocytolysis with good tolerability in human clinical studies, to rapidly advance our IND-approved lead product." Mr. Humberto Antunes, co-founder of Sagesse Bio, partner of Gore Range Capital, former Chairman and CEO of Galderma/Nestlé Skin Health, an internationally renowned executive in skin health industry, comments: "The strategic goal of Sagesse Bio is to deliver innovative and life changing therapies to patients with an initial emphasis on focal fat destruction." "We are thrilled to build this historic partnership: RNAi therapeutic candidate is moving into medical aesthetic product development for body contouring," commented Dr. Patrick Lu, founder, Chairman of the board, executive director, President and CEO of Sirnaomics. "The joint expertise and resources from both Sirnaomics and Gore Range Capital are setting up a strong foundation for a tremendous growth potential of Sagesse Bio with its accelerated product development speed." The board of directors of the Company has approved, and the board of directors and the stockholders of Sagesse Bio have approved, a series of agreements in relation to the partnership (the "Agreements"). The Company and Sagesse Bio have signed the Agreements, which shall become effective only upon being approved by the shareholders of the Company at an upcoming general meeting. Under the partnership arrangement, Sagesse Bio will initiate a clinical evaluation immediately for its leading product candidate, SGY-101, with scientific and technical support from Sirnaomics, receiving assignment and licensing of certain relevant intellectual property rights for the licensed product. In return, Sirnaomics will receive milestone payments of up to US$33 million and a majority equity position of Sagesse Bio with value of approximately US$36 million upon successful equity or debt financing in the future at a minimum pre-financing valuation of Sagesse Bio at US$60 million. Gore Range Capital is responsible for initial funding and building the executive management team and advisory board. In addition, with its well-built domain expertise and extensive networks in the skin health industry, Gore Range Capital is able to provide a hands-on approach for Sagesse Bio's fundraising and business development challenges. About Gore Range Capital Gore Range Capital is focused on investments in the skin health businesses. Gore Range's approach is simple: "We invest in what we know." Over the course of their respective careers the Gore Range team has built domain expertise and extensive networks across multiple areas of healthcare. Through Gore Range Capital, capabilities are channeled to focus on the largest organ and the most visible manifestation of personal identity: the skin. At Gore Range, the hands-on approach of operationally focused private equity is blended with the early-stage guidance needed in venture capital. Formed in 2015, Gore Range works closely with portfolio companies and industry leaders to bring skin health innovations to market. To accomplish this mission, Gore Range leverages its team of experienced healthcare investors, leaders, and practitioners to bring strategic, financial and scientific expertise to its investments. Learn more at: . About Sirnaomics Sirnaomics is an RNA therapeutics biopharmaceutical company that focuses on the discovery and development of innovative drugs for indications with unmet medical needs and large market opportunities. Sirnaomics is the first clinical-stage RNA therapeutics company to have a strong presence in both Asia and the United States. Based on its proprietary delivery technologies, a polypeptide nanoparticle RNAi platform and GalNAc RNAi platform, GalAhead™, Sirnaomics has established an enriched drug candidate pipeline. STP122G, which represents the first drug candidate utilizing the Company's GalAhead™ mxRNA technology, is currently in Phase I development. STP237G is the first dual-targeted drug based on a GalAhead™ muRNA technology and is in the late stage of preclinical development. The Company has also had multiple successes with oncology applications through its clinical programs for STP705 and STP707. With the establishment of the it manufacturing facility in China, Sirnaomics is undergoing a transition from a biotech company to a biopharma corporation. Learn more at: . CONTACT: USA Media Contact: George Ji, MBA Head of Finance and Administration Email: [email protected] Asia Media Contact: Johnson Shen, M.A. Senior Business Manager for Investor Relations Email: [email protected] SOURCE Sirnaomics

Phase 1Phase 2

02 Apr 2024

·www.biospace.com

Nordic Group B.V. Through Its Subsidiary Nordic Pharma, Inc. (U.S.), to Present Data on LACRIFILL® Canalicular Gel, a Novel Therapy for Dry Eye, at the American Society of Cataract and Refractive Surgery Annual Meeting

BERWYN, Pa.--(BUSINESS WIRE)-- Nordic Pharma, Inc., a subsidiary of Nordic Group B.V., will be presenting data on LACRIFILL® Canalicular Gel, a novel therapy for dry eye symptoms, during the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting in Boston, MA on April 5-8, 2024. LACRIFILL Canalicular Gel is a cross-linked hyaluronic acid derivative and is FDA-cleared to temporarily block tear drainage by the occlusion of the canalicular system. “These are truly exciting times for Nordic Pharma as we near the U.S. launch of LACRIFILL Canalicular Gel, a key milestone in our global expansion strategy,” said Charlotte Phelps, CEO of Nordic Pharma. “The recent acquisition of Visant Medical along with Amring Pharmaceuticals becoming Nordic Pharma, Inc., has increased our internal know-how and assets. And with our strong U.S. leadership team and the invaluable support of our Medical Advisory Board, I firmly believe that Nordic Pharma is well-positioned to thrive as a new specialty ophthalmic player and enhance patient care by introducing this novel therapy for dry eye.” “As chairperson of the LACRIFILL U.S. Medical Advisory Board, I am excited about the potential of employing a cross-linked hyaluronic lacrimal filler to optimally occlude the canalicular system to maximize tear film preservation in patients with dry eye symptoms,” said Eric D. Donnenfeld, MD. ASCRS attendees are invited to stop by booth #1245 to learn how LACRIFILL Canalicular Gel is changing practice and changing lives. Attendees will also have the opportunity to be among the first Eye Care Professionals to place orders. LACRIFILL Canalicular Gel will be featured at various Refractive and Cornea Day sessions throughout the meeting, including the “LACRIFILL: A Paradigm Shift in Dry Eye Intervention” panel, which will be held on Saturday, April 6th, 2024 and will include the distinguished faculty of Eric Donnenfeld; MD, Preeya Gupta, MD; Darrell White, MD; and Kevin J. Corcoran, COE, CPC, CPMA, FNAO and the Principal of Corcoran & Corcoran. Mark Packer, MD, FACS, CPI, who will be moderating the panel said, “As a lacrimal filler, cross-linked hyaluronic acid provides a new approach to preservation of the tear film, protecting and conforming to delicate tissues while blocking outflow. LACRIFILL Canalicular Gel transforms treatment of the ocular surface, with demonstrated safety and effectiveness for both signs and symptoms of dry eye.” Chief Commercial Officer of Eye Care U.S., Jai Parekh, MD, MBA said, “I am thrilled for Nordic Pharma to be presenting data on LACRIFILL Canalicular Gel at a meeting as important as ASCRS. This is where science and innovation come together, making it the perfect environment to highlight this novel therapy for dry eye.” For more information and ordering details for LACRIFILL Canalicular Gel visit lacrifill.com. About Nordic Group B.V. Nordic Group B.V. is a privately owned, medium-size international pharmaceutical company which focuses on the development and commercialization of specialty products. Portfolio enhancement has been accomplished through targeted developments and focused acquisitions to build a foundation in Eye Care, Rheumatology and Women’s Health. Nordic Pharma has established deep roots throughout Europe, and more recently, expanded outside of Europe with increased acquisitions worldwide. Nordic Pharma is a part of SEVER Life Sciences, a holding company created in 2019 that brings together three diverse but complementary companies that offer a wide range of products, pharmaceutical development services and delivery technologies. About Nordic Pharma, Inc. Nordic Pharma, Inc., subsidiary of Nordic Group B.V., is partnered with well-established global biopharmaceutical companies and is uniquely positioned to leverage its expertise in bringing biotechnology derived medicines, sterile manufacturing and other state-of-the-art technologies to the marketplace. Safe Harbor This press release contains forward-looking statements, including, without limitation, statements related to Nordic Group /Nordic Pharma’s business developments and the implementation of Nordic Group /Nordic Pharma’s strategic initiatives. Because these statements reflect Nordic Group /Nordic Pharma’s current views, expectations and beliefs concerning future events, these forward-looking statements involve risks and uncertainties that could cause actual developments and results to differ materially from Nordic Group /Nordic Pharma’s expectations. These factors include, but are not limited to, general market conditions, regulatory trends, changes in the financial conditions of third parties dealing with Nordic Group /Nordic Pharma, and other factors that could affect Nordic Group /Nordic Pharma’s business and financial performance. Nordic Group /Nordic Pharma does not assume any obligation to publicly update any forward-looking statements, whether as a result of new information, future developments or otherwise. Disclaimer All educational content of the ASCRS Annual Meeting is planned by its program committee, and ASCRS does not endorse, promote, approve, or recommend the use of any products, devices, or services. View source version on businesswire.com: Contacts Nordic Pharma, Inc. Kate Popova Contracts Administration Lead 610-285-1699 ekaterina.popova@nordicpharma.com Gail Feerrar Director Sales and Marketing 610-285-7152 gail.feerrar@nordicpharma.com Source: Nordic Pharma, Inc. View this news release online at:

Acquisition

14 Mar 2024

·www.prnewswire.com

Empower Aesthetics Highlights Recent Strategic Partnerships: Uplifting Businesses of Medical Aesthetic Industry Entrepreneurs

Private Equity-Backed Platform Pursues New Clinical Partnerships and Sparks Growth of Medical Aesthetics Industry Across the U.S. CHICAGO , March 14, 2024 /PRNewswire/ -- Empower Aesthetics ("Empower" or "the Company"), a national medical aesthetics platform, continues its fast-paced growth while at the same time seeking new clinical partnerships to build out the platform. Empower Aesthetics was formed in July 2023 by Shore Capital Partners ("Shore" or "Shore Capital"), a Chicago-based private equity firm focused on microcap investing. Under the leadership of Chief Executive Officer, Alyssa Rapp and Empower's Board of Directors, the Company has solidified four recent partnerships with leading medical aesthetics practices in key U.S. markets: DermaTouch RN Founded in 2006 by Renee Moschitto, Registered Nurse and Founder of the Texas Association of Aesthetic Nurses, DermaTouch RN is a state-of-the-art aesthetic and wellness center that offers minimally invasive medical treatments. Ranked as a top 20 provider of Botox and Juvederm in the country, DermaTouch is consistently recognized as an "Advanced Injector" site and is one of the largest and highest rated providers of Botox, Juvederm and CoolSculpting® ELITE in the Houston area. AWSkin Co. Founded in 2008 in Murfreesboro, Tennessee by Board Certified Nurse Practitioner Amy Hatcher, AWSkin Co. is a medical spa and wellness center offering cosmetic injectables, advanced skincare services, wellness therapies and more. AWSkin Co. has three locations in Cool Springs, Franklin, and Murfreesboro, Tennessee. The Artistry of Face Founded in 2016 by Nurse Practitioner Kelly Heffernan, Artistry of Face offers neurotoxin procedures, dermal filler procedures, body contouring, energy and light-based treatments, as well as a wide range of facial treatments. The practice currently operates out of locations in Albany and Glen Falls, New York. BCRN Aesthetics Founded in 2012 as Rejuviface by Bri and rebranded as BCRN Aesthetics in 2017 by Registered Nurse and Galderma Aesthetic Injector Network (GAIN) Trainer Bri Collins, BCRN Aesthetics is home to Houston's leading advanced aesthetic injectors. The practice's always-evolving knowledge of aesthetics, combined with their unwavering dedication to exceptional customer service and top-tier medical training, makes it one of the most sought-after med spas in the Houston area. "We are committed to building a constellation of clinical partners that are amongst the brightest stars in the space, who deliver and uphold the highest standards of clinical excellence," said Rapp. "The prospect of establishing additional clinical partnerships in the immediate future is a source of great enthusiasm for both me, our executive leadership team and Empower's Board of Directors." Empower Aesthetics is actively pursuing an acquisition strategy, looking for like-minded, growth-oriented entrepreneurs in aesthetics to join a trusted network of clinical leaders, share best practices and deliver superior clinical outcomes. By implementing strategic and operational initiatives intended to elevate the Company's partners, Empower Aesthetics helps clinical leaders grow their businesses, achieve their financial goals, streamline operations and connect with new clients. This private equity-backed support supplies Empower's partners with the resources needed to help grow their businesses, invest in employees, fine-tune operations and see more patients. To learn more about Empower Aesthetics, please visit , or email [email protected]. About Empower Aesthetics Empower Aesthetics is a national aesthetics platform that provides the tools, support and strategy to empower aesthetic owners and practices to reach new heights while maintaining the highest quality of care. With corporate presence in Chicago, Illinois and Austin, Texas, Empower is looking for providers with whom to partner and grow. To learn more about Empower Aesthetics, please visit , or email [email protected]. About Shore Capital Partners Shore Capital, a Chicago-based private equity firm with an office in Nashville, is an investor in microcap companies in the Healthcare, Food and Beverage, Business Services, Industrial, and Real Estate industries. Shore's strategy is to support management partners to grow faster with less risk, through access to capital; world-class board and operational resources; and unmatched networking, development, and shared learnings across the portfolio. From 2020-2023 Shore received recognition from Inc. Magazine as a 4x Top Founder-Friendly Investor and by Pitchbook for being the global leader in private equity total deal volume. Shore targets investments in proven, successful companies with superior management teams, stable cash flow, and significant potential to grow through industry consolidation and organic growth to generate value for shareholders. Shore has approximately $6 billion of assets under management through various investment vehicles. For more information, please visit . Media Contact: Alec Miszuk | Fishman PR | [email protected] | (630) 484-0797 SOURCE Empower Aesthetics

Executive ChangeAcquisition

100 Deals associated with Hyaluronic acid

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KEGG	Wiki	ATC	Drug Bank
D08043	Hyaluronic acid	-	DB08818

R&D Status

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Indication	Highest Phase	Country/Location	Organization	Date
Osteoarthritis, Knee	Phase 2	-	-	01 Jun 2021
Alpha 1-Antitrypsin Deficiency	Phase 2	-	Actelion Pharmaceuticals Ltd.	-
Asthma	Phase 2	-	Actelion Pharmaceuticals Ltd.	-

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Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


NCT05130814 (RISE_UP, CTgov)	Not Applicable	Pressure Ulcer	48	bandage+zinc+hyaluronic acid gauze plus polyurethane foam+hyaluronic acid sodium salt+metallic silver (Control Group)	jgyvnnfjbe(itxgduqisq) = msmffktqrg bzejzofqpq (rekvxcttvb, amhwpkigvl - hbkjphrkgz) View more	-	28 Jan 2025
				bandage+zinc+hyaluronic acid gauze plus polyurethane foam+hyaluronic acid sodium salt+metallic silver (EmoLED Group)	jgyvnnfjbe(itxgduqisq) = phxfxcbovf bzejzofqpq (rekvxcttvb, xvfzasdyla - ohzdpbqczs) View more
ASTRO2024	Not Applicable	Prostatic Cancer	-	Non-Animal Stabilized Hyaluronic Acid (NASHA) (NASHA rectal spacer)	tejyrukxsg(uxgrngnrwr) = tnydehrvyl uubonrdvds (dwzgnzustq ) View more	-	01 Oct 2024
				Non-Animal Stabilized Hyaluronic Acid (NASHA) (No spacer)	tejyrukxsg(uxgrngnrwr) = onkhpjgofj uubonrdvds (dwzgnzustq ) View more
NCT03460158 (CTgov)	Phase 4	-	101	Restylane-L®	stpdbhghpa(clzghpddca) = hczipfmjbn gkfvbamtiq (erydlctkds, jvqszaqxjv - nbnwowxowd) View more	-	27 Sep 2024
EADV2022	Not Applicable	Blepharoptosis	20	hyaluronic acid	pibxiwypvg(qsmzdkgrvg) = qtfcvvdfpy alcfvhmxsd (rkmilgsjbx ) View more	-	07 Sep 2022
				Pneumatic injection of Hyaluronic Acid	pibxiwypvg(qsmzdkgrvg) = ysniecfhyu alcfvhmxsd (rkmilgsjbx ) View more
ERS2022	Not Applicable	Infectious Diseases	147	Hypertonic saline solution without hyaluronic acid (HSS)	(gruqhhqzde) = usxnrqtaky ikhwioudwg (iskbffrmou )	-	04 Sep 2022
				Hypertonic saline solution with hyaluronic acid (HSS+HA)	(gruqhhqzde) = vntplxpzwm ikhwioudwg (iskbffrmou )
DDW2022	Not Applicable	Weight Loss	-	CONJUGATED LINOLEIC ACID (CLA), COLLAGEN, AND HYALURONIC ACIDConjugated Linoleic Acid (CLA), COLLAGEN, AND HYALURONIC ACID (Conjugated Linoleic Acid (CLA))	xvmnrpkijo(pvgihzunuc) = zuqlqafyzl ytjzqwxhxg (vgohdpwdvv ) View more	-	24 May 2022
ARVO2022	Not Applicable	Lacerations	-	Moxifloxacin NPs	nvqdnrsyuf(wrybxaqgaf) = mcccselwwi etvwxpbiqf (yiogrmqast ) View more	-	01 May 2022
				Moxifloxacinglycidyl methacrylate-hyaluronic acid (HAGM) (Gelatin methacryloyl (GelMA) and glycidyl methacrylate-hyaluronic acid (HAGM) hydrogel)	keczvgikok(nrhyrpzvas) = juamdnmzxq qckbjkpdos (gciacfkebh )
IRCT2015081723666N1 (Pubmed \| BMC Womens Health)	Phase 3	Endometrial Carcinoma	50	Hyaluronic acid gel (Ovarian suspension)	zxougzuwlo(getxndtbml) = lnnhrgdxjg dpmojlovbf (cghwbvukwf ) View more	-	11 Feb 2022
				Hyaluronic acid gel	zxougzuwlo(getxndtbml) = woriakatue dpmojlovbf (cghwbvukwf ) View more
P558 (EBMT2020)	Not Applicable	Hematopoietic stem cell transplantation	32	Hyaluronic Acid Bladder Instillation	(pyonfcghwr) = eiswnvmtot hfxeohlgvy (jdjgtnxuzt ) View more	-	29 Aug 2020
				Intravesical Hyaluronic Acid (Conventional Measures (hyperhydration, transfusion support, vesical irrigation))	(adarratdfo) = nuampywmqe faldfxlktv (txywdchduj )
WCO_IOF_ESCEO2020	Not Applicable	Osteoarthritis, Knee	72	Intra-articular Hyaluronic Acid Injection	aanceyylja(jlxdqroxct) = ejkvvdadeu jpcshomumm (natwcipecw ) View more	Positive	20 Aug 2020

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