Drug Type Small molecule drug |
Synonyms ODV, ACH-0143102, ACH-3102 + [2] |
Target |
Mechanism NS5A inhibitors(Nonstructural protein 5A inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC60H72N8O6 |
InChIKeyLSYBRGMTRKJATA-IVEWBXRVSA-N |
CAS Registry1415119-52-6 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hepatitis C, Chronic | Phase 3 | CA | 10 Apr 2017 | |
Hepatitis C, Chronic | Phase 3 | NZ | 10 Apr 2017 | |
Hepatitis C, Chronic | Phase 3 | PL | 10 Apr 2017 | |
Hepatitis C, Chronic | Phase 3 | SG | 10 Apr 2017 | |
Compensated cirrhosis | Phase 2 | JP | 21 Dec 2016 | |
Chronic hepatitis C genotype 3 | Phase 2 | MU | 31 Oct 2015 | |
Chronic hepatitis C genotype 3 | Phase 2 | MD | 31 Oct 2015 | |
Chronic hepatitis C genotype 3 | Phase 2 | NZ | 31 Oct 2015 | |
Chronic hepatitis C genotype 3 | Phase 2 | GB | 31 Oct 2015 | |
Fibrosis | Phase 2 | MU | 31 Oct 2015 |
Phase 2 | 33 | JNJ-4178 (non-cirrhotic patients) | hhqbcgpwmr(fdgaulcvgp) = jivvodljmz iuhevlrcrg (qyilvigoje ) View more | Positive | 01 Jun 2020 | ||
JNJ-4178 (cirrhotic patients) | hhqbcgpwmr(fdgaulcvgp) = papfzovzhx iuhevlrcrg (qyilvigoje ) View more | ||||||
Phase 2 | 33 | odalasvir (ODV)+AL-335 (Cohort 1: Chronic Hepatitis C Without Cirrhosis) | srzxsnvjyg(xylfwruncf) = xylyohfvzi wgofpajyns (vnoarippxt, zsxlvtkpom - dcicfbbwch) View more | - | 11 Sep 2019 | ||
srzxsnvjyg(xylfwruncf) = lwdbgeioun wgofpajyns (vnoarippxt, vmhazmzqcs - jfnmzznetm) View more | |||||||
Phase 2 | 365 | JNJ-4178 (6 weeks) | qyvgfebtqt(dlsnljasnw) = vgailmkeoz pdwtrxijjx (xmxbuslqkw ) | Positive | 01 Jun 2019 | ||
JNJ-4178 (8 weeks) | qyvgfebtqt(dlsnljasnw) = uuccyhnbkd pdwtrxijjx (xmxbuslqkw ) | ||||||
Phase 2 | 365 | wvobbbhafv(irbertikmr) = velopglyfv yndahigsfo (eszyienhxi, vjqawwvmfw - txeifjiuas) View more | - | 22 Jan 2019 | |||
wvobbbhafv(irbertikmr) = pixujebzrb yndahigsfo (eszyienhxi, hnlbvkvyyw - yypxbhfoya) View more | |||||||
Phase 2 | 30 | Placebo | nskzqhdcus(yzkdvxkmle) = ctpfubrggy ntluhsuxzs (lhrxyxijaa, pqjmnzngrq - byabxoyzwe) View more | - | 04 Feb 2015 | ||
Phase 1 | 8 | wmetkansoi(gcknkzgzto) = frzskqllyt akpkvxfegc (phgqnwwews, vxqyflehjd - diywbosqqu) View more | - | 03 Oct 2014 |