Drug Type Monoclonal antibody |
Synonyms IMC 3C5, LY-3022856 |
Target |
Mechanism VEGFR3 antagonists(Vascular endothelial growth factor receptor 3 antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 1 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Colorectal Cancer | Phase 1 | US | 26 Sep 2016 | |
Neoplasms | Phase 1 | - | 06 Apr 2011 | |
Advanced Malignant Solid Neoplasm | Phase 1 | US | 01 Mar 2011 |
Phase 1 | 44 | (5 mg/kg IMC-3C5) | eicgzemrkn(hoxvhzzxfs) = rxuwakhbuy iqtvnkensx (cdayfjqmxm, jrfejxmmms - cihyeappqp) View more | - | 17 Jun 2019 | ||
(10 mg/kg IMC-3C5) | eicgzemrkn(hoxvhzzxfs) = pkaasxeybt iqtvnkensx (cdayfjqmxm, zjkbusqfaw - hrvqjkudgv) View more | ||||||
Phase 1 | 44 | (solid tumors) | iskbwmdlzd(pnwbnwfyak) = Treatment-emergent adverse events (TEAEs) of any grade included in ≥15 % of all patients were: nausea (41 %), fatigue (32 %), vomiting (30 %), decreased appetite (27 %), pyrexia (25 %), peripheral edema (23 %), and urinary tract infection (UTI, 20 %). epvsujpetd (uxlfsjclau ) View more | Negative | 01 Oct 2016 | ||
(CRC) |