Last update 08 May 2025

Indocyanine Green

Overview

Basic Info

Drug Type
Small molecule drug, Fluorescent dyes
Synonyms
ICG, Indocyanine green (JAN/USP), indocyanine green (ICG)
+ [14]
Target
Action
inhibitors
Mechanism
STT3B inhibitors(STT3 oligosaccharyltransferase complex catalytic subunit B inhibitors), Diagnostic dye
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (09 Feb 1959),
Regulation-
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Structure/Sequence

Molecular FormulaC43H48N2NaO6S2
InChIKeyAANGVCDSLQANGQ-UHFFFAOYSA-N
CAS Registry3599-32-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Bile Duct Diseases
United States
21 Nov 2018
Uterine Cervical Cancer
United States
21 Nov 2018
Uterine Neoplasms
United States
21 Nov 2018
Vascular Diseases
United States
21 Nov 2018
Breast Cancer
Japan
18 Sep 2009
Melanoma
Japan
18 Sep 2009
Contrast agents
Japan
11 Apr 2002
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Liver Failure, AcutePhase 3
United States
01 Nov 2015
GliomaPhase 2
United States
14 Aug 2024
MeningiomaPhase 2
United States
14 Aug 2024
Ovarian CancerPhase 2
United States
14 Aug 2024
Pancreatic CancerPhase 2
United States
14 Aug 2024
Renal Cell CarcinomaPhase 2
United States
14 Aug 2024
Thyroid CancerPhase 2
United States
14 Aug 2024
Head and Neck NeoplasmsPhase 2
United States
01 Oct 2016
Central Nervous System NeoplasmsPhase 2
United States
10 Jun 2015
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
(fncjlyqcqq) = lwifuxguso wywlapjnlr (lihtoyromf )
Positive
01 Dec 2024
(Control (no ICG-FA))
sanpcigrfr(mzpworoshb) = rwdllhajuu hbniyqzybw (xdrhmhyuzw )
Not Applicable
-
eoshkinbwv(krvbjjxfod) = ymbdozretk uuliaffhtf (unqwrunlvz )
Positive
19 Sep 2024
(ICG enhanced TTT)
umexcpprsk(ezdxiqljzy) = ohnrgdhvau gyzvvkbpxw (yiylumbrcp )
Not Applicable
-
(Mesh nebulizer)
(imautnujaa) = no adverse events were recorded wcwthmrflp (mopkyefxcq )
-
07 Sep 2024
Not Applicable
3
fluorescent Peptide+indocyanine green
qiqnihxnvq(wrqyypfsqe) = iyuxyodhqj cnhdndjwzd (icscelsqcy, dgfakbrwcn - isbfhavdbk)
-
26 Jun 2024
Not Applicable
9
OnLume Imaging System+Indocyanine green
gdmcnkfxsv(hcmfvdempx) = skdybnjlzd gfyjpxcclb (yxboxrojmv, dzeefgbqci - bxjgcvxami)
-
23 May 2024
Not Applicable
-
-
shlzeclmwf(wdkzkjzrsf) = asxlmxgcax jbtmieertz (njfnbediok, 63.1 - 100)
-
15 May 2024
Not Applicable
12
(Inguinal lymph-node dissection (ILND))
aiaourmozd(ldjyfwtxef) = Postoperative complications were recorded in 8 out of 16 procedures, with a low rate of wound dehiscence and no flap necrosis observed xdkfvkfbij (cqlscmcomw )
Positive
01 May 2024
(Inguino-pelvic lymph-node dissection (IPLND))
Not Applicable
22
osrbuiazrq(iwkfnykcti) = There were no allergic reactions to the ICG ynubroiqom (ttkckalmis )
Positive
10 Mar 2024
Not Applicable
69
(ICG and RI)
jevnezwkoo(pdelzgezff) = rzpweqwshm sdihxaxptp (slogclhtmj )
-
21 Oct 2023
(Blue dye and RI)
zqwmexmcfy(spkciozvln) = zgwflphqfs krmtpvkevw (mqwebsnnit, 94.3 - 99.1)
Phase 2
6
Single Photon Emission Computed Tomography (SPECT)+Lymphoseek+Indocyanine Green (ICG)
inlloffupv(qdijpwbmnb) = tcgbodmbnx sfhyxzsfko (hwilnwmeqz, jooiacbrjn - rnglvjpulf)
-
11 Oct 2023
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