Last update 29 May 2025

Fosrolapitant/Palonosetron

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
罗拉匹坦(前药)/帕洛诺司琼, H R20013, H-R20013
+ [3]
Action
antagonists
Mechanism
5-HT3A receptor antagonists(5-hydroxytryptamine receptor 3A antagonists), NK1R antagonists(Neurokinin 1 receptor antagonists)
Therapeutic Areas
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC27H29F6N2O8P
InChIKeyPKXQGSOAMISYFP-LJXNEXSDSA-N
CAS Registry2573694-38-7

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Chemotherapy-induced nausea and vomiting
China
29 May 2025
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
NauseaPhase 3
China
21 Sep 2022
Solid tumorPhase 3
China
21 Sep 2022
VomitingPhase 3
China
21 Sep 2022
Malignant Solid NeoplasmPhase 1
China
25 Aug 2022
Nausea and vomitingPhase 1
China
25 Aug 2022
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-HR20013 + Dexamethasone
ebrhmecgte(vntnoncuzo) = pxraximajd udxqppdbuw (vnhrcmxpbh )
Non-inferior
02 Dec 2024
fosaprepitant + palonosetron + dexamethasone
ebrhmecgte(vntnoncuzo) = arwmrlkrdo udxqppdbuw (vnhrcmxpbh )
Phase 3
-
(Cycle 1)
qzobjsgwhl(nqbntszhig) = pqwogmwjak qbbrbnajrr (ltcuvrdahe )
Met
Non-inferior
08 Sep 2024
FAPR+PALO+DEX
(Cycle 1)
qzobjsgwhl(nqbntszhig) = whugobvxak qbbrbnajrr (ltcuvrdahe )
Met
Phase 3
750
HR20013+地塞米松
szktvvjybv(dovmksbesi) = yrffityqly letcyzqoil (vvbprjdxqs )
Positive
08 Jul 2024
福沙匹坦+帕洛诺司琼+地塞米松
szktvvjybv(dovmksbesi) = zxlyebxrrn letcyzqoil (vvbprjdxqs )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free