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FRIDAY, March 24, 2023 -- Endless worry, irritability and insomnia are all symptoms of a possible anxiety disorder . Luckily, there are numerous anxiety medications that can help ease the condition. Joy Alonzo , a specialist in the pharmacotherapy of mental disorders at Texas A&M's College of Pharmacy, said recently, “If you understand the different types of medication, then you can become a better advocate for your anxiety treatment. Anxiety is one of the most under-treated mental illnesses, and we need to talk more about it.” So, what medications can bring relief from crippling anxiety? According to the Anxiety & Depression Association of America (ADAA), the most common classes of drugs for the treatment of anxiety include: Selective serotonin reuptake inhibitors (SSRIs) Serotonin-norepinephrine reuptake inhibitors (SNRIs) Benzodiazepines Tricyclic antidepressants Here is a rundown on medications for anxiety. Selective serotonin reuptake i nhibitors (SSRIs) SSRIs work by preventing the body from reabsorbing serotonin, which leaves more available for use. The ADAA describes serotonin as a neurotransmitter that plays a role in feelings of well-being and happiness. SSRIs are considered the first-line treatment for all types of anxiety disorders. A higher dose may be required when treating obsessive-compulsive disorder (OCD). Common side effects : Insomnia Sleepiness Sexual dysfunction Weight gain Dry mouth Common SSRIs: Citalopram ( Celexa ) Escitalopram ( Lexapro ) Fluoxetine ( Prozac , Sarafem ) Paroxetine ( Paxil , Paxil CR , Pexeva , Brisdelle ) Sertraline ( Zoloft ) What else you should know about SSRIs: SSRIs may make it easier to engage in psychotherapy and other wellness activities They may help improve other symptoms of anxiety, including headaches and sleep disturbances Initial side effects typically disappear after four to eight weeks SSRIs are safe for long-term use Check with your provider before stopping their use or changing your dose Serotonin-norepinephrine reuptake inhibitors (SNRIs) This class of medication is also a first-line treatment for anxiety disorders, except for OCD. It works by inhibiting the brain cells' reabsorption of both serotonin and norepinephrine. Serotonin is the neurotransmitter that helps with a sense of well-being. According to Anxiety.org , norepinephrine is considered important for its role in the body’s stress response. Common side effects: Anxiety.org states that SNRIs may have more side effects because they affect serotonin and norepinephrine. These side effects may include: Dry mouth Nausea Nervousness Insomnia Drowsiness Dizziness Headache Sexual dysfunction Loss of appetite Agitation Common SNRIs: Venlafaxine (Effexor) Desvenlafaxine ( Pristiq ) Duloxetine ( Cymbalta ) What else you should know about SNRIs Anxiety.org reports that these medications promote neuroplasticity in the brain. This may make your brain more flexible. There is evidence that these medications work best in combination with psychotherapy. But there is one important caveat. “SSRIs and SNRIs are not an instant fix for symptoms associated with an anxiety disorder, nor do they even provide immediate relief,” Alonzo said. “They work by interacting with the neurotransmitters and receptors in your brain, which can help regulate mood, sleep and energy levels. It is important for patients to understand that these medications may take four to six weeks for full effect.” Benzodiazepines Benzodiazepines are considered a second-line therapy for the treatment of generalized anxiety disorder. According to the ADAA, they work by strengthening the GABA neurotransmitter. This neurotransmitter plays a primary role in feeling calm, muscle relaxation, reduction in brain activity and sleep. Most common side effects: Drowsiness Confusion Dizziness Depression Impaired coordination Vision problems Common benzodiazepines: Alprazolam ( Xanax ) Lorazepam ( Ativan ) Diazepam ( Valium ) What else you should know about benzodiazepines for the treatment of anxiety: They act quickly, but do not stay in the system for long They are not safe for continuous use, and can be addictive May be initiated with a first-line treatment, and then tapered off Do not operate heavy equipment while taking Do not mix with alcohol Not recommended for people with suicidal or addictive tendencies Tricyclic antidepressants According to the Mayo Clinic , tricyclic antidepressants are among the earliest antidepressants. They are often recommended when newer drugs have not been effective. They are not typically used for social anxiety disorder or OCD. They also work by blocking the reabsorption of serotonin and norepinephrine, but their mechanism of action is different and they typically cause more side effects than newer treatments. Common tricyclic antidepressants: Imipramine (Tofranil) Nortriptyline (Pamelor) Desipramine (Norpramin) Clomipramine (Anafranil) Common side effects: Drowsiness Blurred vision Constipation Dry mouth Drop in blood pressure when going from sitting to standing Urine retention Weight loss/weight gain Excessive sweating Tremor Sexual dysfunction What else you should know about tricyclic antidepressants: You should not stop taking these medications abruptly You may need to have blood work done to determine the correct dose Disorientation can occur in older people at higher doses May cause a rapid or irregular heart rate Can increase seizure activity if prone to seizures When to seek treatment for anxiety The National Institute of Mental Health lists these as common symptoms of anxiety: Feeling restless, wound up or on edge Being easily fatigued Having difficulty concentrating Being irritable Having headaches, muscle aches, stomach aches or unexplained pains Difficulty controlling feelings of worry Having sleep problems, such as difficulty falling or staying asleep The ADAA recommends seeking medication for anxiety when you are having physical symptoms, are unable to do what you want because of how you feel or are unable to make life choices because of fear. It is never too early to start treatment. Anxiety treatment can be more effective when used with therapy. It is essential to keep all your appointments with your provider. Do not stop your medication or change the dose without discussing it with your provider. If the side effects affect your daily activities, inform your provider immediately. If, at any time, you feel as though you may be suicidal, reach out to your provider or go to the nearest emergency room. You can also call or text the national suicide prevention hotline at 988. Posted March 2023

Fact.MR, a global research & consulting firm, in their recent version of the report, indicated that the canine separation anxiety treatment market is projected to foresee moderate expansion in 2021 and beyond. Surge in research and development and progressions in drugs along with other therapies in the treatment of canine separation anxiety is encouraging the overall industry. Rise in the adoption of pets as well as expenditure by pet owners is encouraging the industry. “Rise in demand for drug therapy generally utilized for environmental and behavioural modification in the treatment for canine separation anxiety, is booting the industry growth.” states Fact.MR. Growing Adoption Pets Across the Globe to Propel Growth Increase in the adoption of pets in the developed & developing nations, rise in disposable income as well as the subsequent surge in expenditure on animals are amid factors fuelling the industry. Furthermore, rise in the number of veterinary professionals in middle - or low -income nations and ease in the regulatory approvals for innovative drugs is driving this treatment industry. Request a Report Sample to gain comprehensive Market Insights at - Clomipramine to Remain Lucrative Clomipramine is anticipated to be the most preferred drug type. Clomipramine accounts for the biggest revenue share in the industry as a result of expansion in the demand for drugs for the treatment. It is extensively adopted to treat obsessive-compulsive disorders and disorder with an obsessive-compulsive component (e.g. Tourette’s disorder, schizophrenia, depression,). The usage is further increased as it is thought to improve the actions of serotonin and norepinephrine by blocking their re-uptake as well as prolonging their activity. How Big is the Opportunity in The US? The US is likely to reflect strongest growth dynamics in canine separation anxiety treatment industry due to the higher prevalence of canine separation anxiety as well as a consequent rise in the treatment of canine separation anxiety. India China and South Korea will grow at a notable growth pace as a result of the growth of product offerings by major companies. The UK and Germany will continue to be a second-biggest regional market over the assessment period. Mexico, Brazil, South Africa and GCC countries are projected to account for moderate growth pace as a result of lack of awareness amid pet owners. Get Customization on this Report for Specific Country Mergers and Acquisition Remain Prime Focus Area: Fact.MR Survey The canine separation anxiety treatment market appears to be fragmented in nature. Fact.MR’s survey projected that the leading companies continue to fulfill the unmet requirements in the market through inorganic strategies, such as mergers and acquisitions. The updated edition of the report offers widespread coverage of the projected remain significant strategies of the market players. A few of the key companies profiled in the report are Pegasus Laboratories, Inc., Zoetis, Vets4Pets Limited and Merck & Co., Inc. and Pfizer Limited. The latest edition also provides a thorough analysis of the COVID-19 impact on this market. Explore Fact.MR’s Healthcare Reports Canine Influenza Treatment Market: Delve into Fact.MR’s extensive study on the canine influenza treatment market, offering detailed assessment. The study analyses crucial trends that are currently determining, and those which are expected to shape future expansion trajectory, shedding light on the vital dynamics such as drivers, restraints and opportunities. Veterinary Suture Kit Market: The global veterinary suture kit market study published by fact.mr incorporates detailed assessment of the market landscape, taking into consideration value chain analysis, business execution and supply chain analysis across key markets. Canine Parvovirus Market: Fact.MR’s global canine parvovirus market research report provides stakeholders with an exhaustive analysis on key market dynamics, such as the drivers, restraints, opportunities and trends responsible for shaping the future expansion trajectory. About Fact.MR Market research and consulting agency with a difference! That’s why 80% of Fortune 1,000 companies trust us for making their most critical decisions. We have offices in US and Dublin, whereas our global headquarter is in Dubai. While our experienced consultants employ the latest technologies to extract hard-to-find insights, we believe our USP is the trust clients have on our expertise. Spanning a wide range – from automotive & industry 4.0 to healthcare & retail, our coverage is expansive, but we ensure even the most niche categories are analyzed. Reach out to us with your goals, and we’ll be an able research partner.