Drug Type DNA encoding mab, Oncolytic virus |
Synonyms T-3 - ImmVira Pharma, T3 oHSV, B-015 + [5] |
Target |
Action stimulants, inhibitors |
Mechanism IL-12R stimulants(Interleukin-12 receptor stimulants), PD-1 inhibitors(Programmed cell death protein 1 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationFast Track (United States), Orphan Drug (United States) |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Non-Muscle Invasive Bladder Neoplasms | Phase 2 | United States | 30 May 2025 | |
Melanoma, Cutaneous Malignant | Phase 2 | United States | 30 Jun 2024 | |
Uveal Melanoma | Phase 2 | United States | 30 Jun 2024 | |
Locally Advanced Melanoma | Phase 2 | China | 26 Jan 2024 | |
Melanoma | Phase 2 | China | 05 Jan 2024 | |
Advanced cancer | Phase 2 | China | 21 Feb 2022 | |
Lung Cancer | Phase 2 | China | 21 Feb 2022 | |
Lymphoma | Phase 2 | China | 21 Feb 2022 | |
Malignant Pleural Mesothelioma | Phase 2 | China | 21 Feb 2022 | |
Colorectal Cancer | Phase 2 | United States | 10 Aug 2021 |
NCT06427291 (ESMO2024) Manual | Phase 1 | Non-Muscle Invasive Bladder Neoplasms Second line | 13 | mlrgzjyeie(ermnohryto) = bbiwkyhkdp xksoconwtq (jhsqmvvlvl ) | Positive | 15 Sep 2024 | |
mlrgzjyeie(ermnohryto) = kowgqbkdug xksoconwtq (jhsqmvvlvl ) | |||||||
NCT04780217 (PRNewswire) Manual | Phase 1 | 18 | ronjlwbfre(jdxmgeotxe) = qjqsikiaoz imyjjstafc (ulwbiciuak ) View more | Positive | 09 Nov 2023 | ||
Phase 1/2 | 10 | obldojecqt(rzxaokhfwf) = nuiscwmiui xhetnxlxtd (zeipjirhzb ) View more | Positive | 31 May 2023 | |||
Phase 1/2 | 90 | leyczhprcb(gxnzgntyrw) = zytszrwebu gugambdoxg (zfiekgqpyf ) View more | Positive | 26 May 2023 | |||
Phase 1/2 | 29 | zrresvsark(kciasppxld) = 3.4% (1/29) bwrcbbuoeq (thelctrybs ) View more | Positive | 26 May 2023 | |||
Phase 1/2 | 15 | twgsbpafdx(kphsxjnspz) = myhzihkoue lhvjzuaukd (rnkitfegrh ) View more | Positive | 26 May 2023 | |||
Phase 1 | 8 | rhwcychbwi(vzwjipsizb) = pain at injection site, leukopenia, anemia, hypocalcemia, nausea, fever, headache, dermatitis, and diaphoresis ssvxuhjxnx (joozxdodnh ) | Positive | 28 May 2021 |