Drug Type Oncolytic virus |
Synonyms T-3 - ImmVira Pharma, T3 oHSV + [5] |
Target |
Mechanism IL-12R stimulants(Interleukin-12 receptor stimulants), PD-1 inhibitors(Programmed cell death protein 1 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
RegulationFast Track (US), Orphan Drug (US) |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Metastatic melanoma | Phase 2 | AU | 17 Sep 2020 | |
Metastatic melanoma | Phase 2 | US | 17 Sep 2020 | |
metastatic non-small cell lung cancer | Phase 2 | US | 17 Sep 2020 | |
metastatic non-small cell lung cancer | Phase 2 | AU | 17 Sep 2020 | |
Advanced Malignant Solid Neoplasm | Phase 2 | CN | 10 Apr 2020 | |
Breast Cancer | Phase 2 | CN | 10 Apr 2020 | |
Esophageal Carcinoma | Phase 2 | CN | 10 Apr 2020 | |
Non-Small Cell Lung Cancer | Discovery | CN | 21 Apr 2020 | |
Sarcoma | Discovery | CN | 21 Apr 2020 | |
Squamous Cell Carcinoma of Head and Neck | Discovery | CN | 21 Apr 2020 |
NCT06427291 (ESMO2024) Manual | Phase 1 | Non-Muscle Invasive Bladder Neoplasms Second line | 13 | (bvtykwusfy) = zfbetyxcdb lpxszvnrmj (amooteytha ) | Positive | 15 Sep 2024 | |
(bvtykwusfy) = dpybszzzsy lpxszvnrmj (amooteytha ) | |||||||
NCT04780217 (PRNewswire) Manual | Phase 1 | 18 | (dsheaqiykl) = ewtwtrutkz dfytrsgkkd (eozopazxls ) View more | Positive | 09 Nov 2023 | ||
Phase 1/2 | 10 | (yymkbkaswl) = rsyuwhripj frjtqrjgrd (tcrwrvkabm ) View more | Positive | 31 May 2023 | |||
Phase 1/2 | 90 | (cazshgszkz) = vqbsieiyzt xhtzzyqpqx (pgctbzqhgq ) View more | Positive | 26 May 2023 | |||
Phase 1/2 | 15 | (rlvzijemhl) = kffakyfxtd pfzsyxjdrz (czpupaeiez ) View more | Positive | 26 May 2023 | |||
Phase 1/2 | 29 | (ncjmfpaeog) = 3.4% (1/29) wcshboqtaa (hstcgjokly ) View more | Positive | 26 May 2023 | |||
Phase 1 | 8 | (cscksdgicx) = pain at injection site, leukopenia, anemia, hypocalcemia, nausea, fever, headache, dermatitis, and diaphoresis xteinokfja (ekqiaiuctr ) | Positive | 28 May 2021 |