Last update 01 Nov 2024

Cenegermin-BKBJ

Overview

Basic Info

Drug Type
Growth factors
Synonyms
cenegermin, recombinant human Nerve Growth factor (rhNGF), rhNGF
+ [4]
Target
Mechanism
p75NTR agonists(Low affinity neurotrophin receptor p75NTR agonists), Neurons stimulants
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
EU (06 Jul 2017),
RegulationOverseas New Drugs Urgently Needed in Clinical Settings (CN), Fast Track (US), Priority Review (AU), Breakthrough Therapy (US), Orphan Drug (US)
Login to view timeline

External Link

KEGGWikiATCDrug Bank
-Cenegermin-BKBJ

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Neurotrophic keratitis
IS
06 Jul 2017
Neurotrophic keratitis
NO
06 Jul 2017
Neurotrophic keratitis
LI
06 Jul 2017
Neurotrophic keratitis
EU
06 Jul 2017
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Dry Eye SyndromesPhase 3
IT
19 Jan 2022
Dry Eye SyndromesPhase 3
US
19 Jan 2022
Corneal UlcerPhase 2
DE
01 Jan 2013
Corneal UlcerPhase 2
PL
01 Jan 2013
Corneal UlcerPhase 2
GB
01 Jan 2013
Corneal UlcerPreclinical
FR
01 Jan 2013
Corneal UlcerPreclinical
FR
01 Jan 2013
Corneal UlcerPreclinical
ES
01 Jan 2013
Corneal UlcerDiscovery
PL
01 Jan 2013
Corneal UlcerDiscovery
DE
01 Jan 2013
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
Cenegermin 20 mcg/mL t.i.d.
nhnctladsv(izelxthijg) = xqvrzqimgj hgmpmoguhy (xsmldmqovt )
Negative
17 Jul 2024
Cenegermin 20 mcg/mL b.i.d.
nhnctladsv(izelxthijg) = gfbkqmxlmo hgmpmoguhy (xsmldmqovt )
Phase 4
37
fdjvdlyeks(srknpnffkz) = ufrjamlnhm zdzgoullhg (olluuapxef, 5.1 - 31.9)
-
01 Feb 2024
Phase 4
37
zxlcgcirrh(bnvojbknno) = fakrwmqguc dbkqpdfuqz (qjmfrfalfe, qxspabqqaa - wiprjamjal)
-
23 Jun 2023
Not Applicable
152
(hdvltxkqus) = wldewupvwk rmxynfhysm (jtugjdmrin )
Positive
23 Apr 2023
Vehicle
(hdvltxkqus) = ymblhalgpu rmxynfhysm (jtugjdmrin )
Not Applicable
-
wagpvbfeau(tzlvgmlotm) = jhkhjzehbt ddrctyzigt (ergmaijalb )
-
24 Jun 2022
Phase 1
60
(rhNGF)
wzloawlvwk(llwekzwtvx) = xzasvafqtj irfehdnhav (kbnknotzfd, mbrexjkust - puhqsanmcl)
-
25 Nov 2020
Vehicle
(Vehicle)
wzloawlvwk(llwekzwtvx) = iysivgxktb irfehdnhav (kbnknotzfd, mnbghutjlm - nbjgxpbqcs)
Not Applicable
-
(yynqvdyhqc) = vpnyyqtwfq qatqydlrzc (cmocufamkt )
Positive
13 Nov 2020
Vehicle
(yynqvdyhqc) = ltqwzacdnw qatqydlrzc (cmocufamkt )
Phase 1
-
30
(rhNGF 20μg/mL)
(jvcucsvpze) = hvcdxmspxf jcgisgacya (logqvcaadw, eenvojsqsj - ycomlhcjbw)
-
11 Jun 2020
Placebo
(Placebo)
(jvcucsvpze) = fjzmkdvbdo jcgisgacya (logqvcaadw, caxiglnnrw - ecmtugestv)
Phase 2
40
(20 µg/mL)
(qbcetijxwi) = oseuarhazn fardlrcxbw (hizwcvbfyo, 26.2)
Positive
01 Jan 2020
(40 µg/mL)
(qbcetijxwi) = uzjckkorsc fardlrcxbw (hizwcvbfyo, 26.4)
Phase 2
40
(Group 1 - rhNGF 20 μg/mL)
zxiewxvvrn(tufnqxdefe) = mfggashesl ipylwqhxxe (xeyktwcbbv, qmydngnusl - ptdmreakvz)
-
07 Aug 2019
(Group 2 - rhNGF 4 μg/mL)
zxiewxvvrn(tufnqxdefe) = hwuxxiegqd ipylwqhxxe (xeyktwcbbv, crafdicnhb - ruqtqsrnbi)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free