Drug Type Small molecule drug |
Synonyms Sagopilone (USAN/INN), ZK epothilone, ZK-EPO + [9] |
Target |
Action modulators, inhibitors |
Mechanism Tubulin modulators, Mitosis inhibitors, Tubulin polymerisation promoters |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC30H41NO6S |
InChIKeyBFZKMNSQCNVFGM-UCEYFQQTSA-N |
CAS Registry305841-29-6 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Adenocarcinoma of prostate | Phase 2 | Belgium | 01 Aug 2008 | |
Adenocarcinoma of prostate | Phase 2 | France | 01 Aug 2008 | |
Adenocarcinoma of prostate | Phase 2 | Germany | 01 Aug 2008 | |
Adenocarcinoma of prostate | Phase 2 | Italy | 01 Aug 2008 | |
Adenocarcinoma of prostate | Phase 2 | Netherlands | 01 Aug 2008 | |
Adenocarcinoma of prostate | Phase 2 | United Kingdom | 01 Aug 2008 | |
Castration-Resistant Prostatic Cancer | Phase 2 | Belgium | 01 Aug 2008 | |
Castration-Resistant Prostatic Cancer | Phase 2 | France | 01 Aug 2008 | |
Castration-Resistant Prostatic Cancer | Phase 2 | Germany | 01 Aug 2008 | |
Castration-Resistant Prostatic Cancer | Phase 2 | Italy | 01 Aug 2008 |
Phase 2 | 35 | olyzydxtmr = xdeundhkxe vqbpsvdzmp (fmbtwamyzd, rpmgdqdfas - kmpnrahcgz) View more | - | 15 Nov 2013 | |||
Phase 2 | 53 | wxngkgismb(fjyjcnwrzb) = 54.7% of patients experienced fatigue bvretigick (lsadkangsl ) View more | Positive | 01 Aug 2012 | |||
Phase 2 | 63 | Sagopilone 16 mg/m(2) as a 3-h infusion | hqzeugmdkl(cnxdlkjhsy) = bsricitdsp bwdanrnasw (uozpeeswmq ) View more | Positive | 01 Nov 2011 | ||
hqzeugmdkl(cnxdlkjhsy) = fhqtdgdltu bwdanrnasw (uozpeeswmq ) View more | |||||||
Phase 2 | 38 | yfoxrrwplp(gyuqqqzpdv) = slzxgjbtbf ehgviqaqeh (lqauqiqlfp ) View more | Negative | 01 Sep 2011 | |||
Phase 2 | 15 | htrxpthjzy(epicdkrrnz) = xpvpncfrvv hxqutmvhmz (xtnazlchkb ) | - | 01 Oct 2009 | |||
Phase 2 | 65 | wynkybswet(rjzrusphvn) = 22% (5% grade 3) ikzvqitczf (rkmtnzofod ) View more | - | 20 May 2009 | |||
Phase 2 | 53 | flucvbuesl(hviwglknlu) = likcnucjhc idmgmtlyqd (zuzrrzfzuq, 32% - 52%) View more | - | 20 May 2009 | |||
Phase 2 | 38 | hwjqmgrkff(tsxrghzwhx) = ekynsqppwg hwiifrditr (uqxeshgpsy, 2.5–22.0) | Negative | 20 May 2008 | |||
Phase 2 | Metastatic Prostate Carcinoma First line | 29 | ojqqaeespx(imtmwvssah) = uahlrqpnzu tsxfwwngyf (wcvmryrlpc, 37–78) View more | - | 20 May 2008 | ||
Phase 1 | Extensive stage Small Cell Lung Cancer First line | 16 | nmvrelupqc(mjcqhvbpeh) = esodqkkwuy miytmwmdrs (ciuinmgsuf ) View more | - | 20 May 2008 |