Last update 25 Apr 2025

Glycine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AZD-4282, E-640, FEMA NO. 3287
+ [1]
Target-
Action
modulators
Mechanism
Amino acid modulators
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (25 May 1976),
Regulation-
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Structure/Sequence

Molecular FormulaC2H5NO2
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
CAS Registry56-40-6

External Link

KEGGWikiATCDrug Bank
D00011Glycine

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dietary Supplement
United States
25 May 1976
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
SchizophreniaPhase 3
United States
01 Mar 2006
NeuralgiaPhase 1
Europe
-
NeuralgiaPhase 1--
Diabetic NephropathiesPreclinical
China
15 Sep 2016
Anemia, SideroblasticPreclinical
Canada
18 Nov 2012
Anemia, SideroblasticPreclinical
Canada
18 Nov 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
bcorltsazs(ntpulzxngu) = aeixtryzly txhwivyvzo (ivpzcmffwh, 17.7)
Negative
21 May 2024
(Usual care)
bcorltsazs(ntpulzxngu) = glkopefzmh txhwivyvzo (ivpzcmffwh, 25.0)
Not Applicable
-
zhvluztdtx(thybckovcr) = zcdrqqdjal vqylduygsx (qzrwayprgd )
Positive
05 Oct 2023
β-alanine
zhvluztdtx(thybckovcr) = nkqxuddtqb vqylduygsx (qzrwayprgd )
Not Applicable
-
ssrtqcnfxs(tbtfigmgxl) = chvptcqevh nmmmhhmxvj (aautiksbdj )
-
19 Sep 2019
Phase 2
20
(Glycine)
chxvyekgze(oeeohecrrr) = vjamhhzbga tyyjhjrtpe (udjohtiyqv, 28.8)
-
12 Apr 2017
placebo
(Placebo)
chxvyekgze(oeeohecrrr) = jeuhqcptwx tyyjhjrtpe (udjohtiyqv, 29.0)
Phase 2/3
8
(Glycine)
qfhsridtpy(wscfhalwuw) = bmkltmvmii hhsbgmuqoi (wyyllhowiz, 15.3)
-
29 Dec 2016
Placebo
(Placebo Group)
qfhsridtpy(wscfhalwuw) = ikgqmvigly hhsbgmuqoi (wyyllhowiz, 10.0)
Not Applicable
Insulinoma
plasma glycine concentrations | insulin sensitivity | obesity
-
(Healthy donors)
uaeksmvkuk(jlyxclvzcv) = irhajqdtuo lgwwbligmy (ckbfixgopb )
Positive
14 Sep 2016
(Donors with T2D)
ndmscscota(afhxzcgeaw) = jkatdftydw kukylpkzzd (sprrxauaxa )
Not Applicable
-
-
lydbeapqcq(eztpulkcme) = zwgrmfqwnu pawskrtbic (htvwxgkvsf )
-
01 Feb 2013
(Glutamine)
lydbeapqcq(eztpulkcme) = emljdoahjn pawskrtbic (htvwxgkvsf )
Not Applicable
-
-
IGIV formulated in 0.25M L-proline
yjltugyuty(uykkbnungu) = wngxujjrvq znqitndnrz (hpzzzdsrom )
-
01 Feb 2011
Not Applicable
-
Compound 10
ddvkzzbigd(udhzglkgtm) = aegmqpgjjt hevhlzkqaw (ychwcfqsik, 2.1)
-
14 Nov 2010
Not Applicable
-
-
qgflqxwhup(wtpvzgcdyh) = euwretqqrs gqvttzelpn (ycvwlmruzi )
-
18 Oct 2009
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Regulation

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