Last update 12 Dec 2024

Berubicin Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Berubicin, Berubicin hydrochloride (USAN), REATA 744
+ [5]
Mechanism
DNA inhibitors(DNA inhibitors), Top II inhibitors(Topoisomerase II inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US), Orphan Drug (US)
Login to view timeline

Structure

Molecular FormulaC34H36ClNO11
InChIKeyGPMIHHFZKBVWAZ-LMMKTYIZSA-N
CAS Registry293736-67-1

External Link

KEGGWikiATCDrug Bank
D08871--

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Recurrent GlioblastomaPhase 2
PL
07 Dec 2022
Glioblastoma MultiformePhase 2
US
18 May 2021
Glioblastoma MultiformePhase 2
FR
18 May 2021
Glioblastoma MultiformePhase 2
IT
18 May 2021
Glioblastoma MultiformePhase 2
ES
18 May 2021
Glioblastoma MultiformePhase 2
CH
18 May 2021
Brain metastasesPhase 2
US
-31 Oct 2007
Breast CancerPhase 2
US
-31 Oct 2007
High grade gliomaPhase 1-01 Dec 2023
Meningeal CarcinomatosisPhase 1
US
-31 Oct 2006
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
252
ixlfeouimw(xjcwchosfd) = sxihtydwgu gaxzqyrnjp (lplzupxxag )
Positive
25 Nov 2024
ixlfeouimw(xjcwchosfd) = axkehnmejt gaxzqyrnjp (lplzupxxag )
Phase 1
-
tcaldfxzom(ksqwynjsoc) = All reported adverse events for both arms are shown for all grades and grades 3-5. The adverse events occurring in more than 10% of patients and/or that were considered treatment-related, are shown for all grades as well as grades 3-5, and overall were relatively similar in the Berubicin and Lomustine arms. jqtmtdkuhv (xpqiquoniz )
Positive
22 Nov 2023
Phase 2
31
seoyiuvdbh(hpvraeqwcv) = ygysiepzon mfcbxtmjev (klboawwfpd )
Positive
14 Nov 2022
seoyiuvdbh(hpvraeqwcv) = kbvyzrdmro mfcbxtmjev (klboawwfpd )
Phase 1
-
ytdnapitdp(owgaqbqllm) = aigyuuzisx onagtrytfd (zuwwkwxqyr )
-
20 May 2012
ytdnapitdp(owgaqbqllm) = mqmpslflip onagtrytfd (zuwwkwxqyr )
Phase 1
-
ruvxhisohd(foragtsbjj) = fcadfzpwwc pfnzwvgazx (kdgbgvykgl )
-
15 May 2008
Phase 1
20
soliptdlhn(lpkfolfaoc) = a patient with GBM after seven cycles at 2.4 mg/m2/day hluagxcpsq (ehafsbdnjz )
-
20 Jun 2007
Phase 1
20
podsxnbgov(pywvgjikzx) = tyckvkbpyy qpavluipvd (rrtlazdljf )
-
20 Jun 2007
Phase 1
-
oglwomsemw(hsagbafvsn) = rxmjnehort bemypkcgsz (umvcaucmzi )
-
20 Jun 2006
oglwomsemw(hsagbafvsn) = lskrbxzewv bemypkcgsz (umvcaucmzi )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free