Last update 24 May 2025

Anrikefon

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
HSK 21542, HSK-21542, HSK21542
+ [1]
Action
agonists
Mechanism
κ opioid receptor agonists(Kappa opioid receptor agonists)
License Organization-
Drug Highest PhaseApproved
First Approval Date
China (13 May 2025),
RegulationPriority Review (China)
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Structure/Sequence

Molecular FormulaC39H57N7O5
InChIKeyVWXDZAZSCZVCPV-YFRBGRBWSA-N
CAS Registry2269511-95-5

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pain, Postoperative
China
13 May 2025
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Uremic pruritusNDA/BLA
China
23 Sep 2024
Chronic Kidney Disease-Associated PruritusNDA/BLA
China
26 Jun 2024
PruritusPhase 2
China
28 Feb 2024
Chemical and Drug Induced Liver InjuryPhase 2
China
16 Sep 2021
Hepatitis APhase 2
China
16 Sep 2021
Liver Diseases, AlcoholicPhase 2
China
16 Sep 2021
AnalgesiaPhase 2
China
01 Jul 2020
Chronic Kidney DiseasesPhase 1
China
10 Oct 2023
UremiaPhase 1
China
15 Jun 2021
Acute PainPhase 1
China
09 Jan 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
6
[14C]HSK21542 2 μg/0.212 μCi/kg
hqahpzawye(usgglhqcdg) = zrzfetitpt widldhextk (ugzsafuljg )
-
01 Nov 2023
Phase 2
41
ezjybtvkwu(nvcljvcqsj) = mwznpepnmx qilpedbduk (rtdruuwdzg )
Positive
01 Jan 2023
ezjybtvkwu(nvcljvcqsj) = xjsszncbox qilpedbduk (rtdruuwdzg )
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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