Last update 21 Nov 2024
Girocitinib
Last update 21 Nov 2024
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms |
Target |
Mechanism JAK1 inhibitors(Tyrosine-protein kinase JAK1 inhibitors), TYK2 inhibitors(Tyrosine-protein kinase 2 inhibitors) |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
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Structure
Molecular FormulaC17H18N4O3 |
InChIKeyZFQNHUSKKDBFHY-GRYCIOLGSA-N |
CAS Registry2222137-79-1 |
Related
18
Clinical Trials associated with GirocitinibA Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of TLL-018 in Participants With Moderate-to-Severe Chronic Spontaneous Urticaria With Inadequate Controll to Second Generation H1-antihistamines
A Phase 3, Randomized, Double-Blind, Positive-controlled, Head-to-Head Monotherapy Study Comparing TLL-018 to Tofacitinib in Subjects With Active Rheumatoid Arthritis With Inadequate Response or Intolerance to Biologic DMARDs (bDMARDs)
评价TLL-018与托法替布头对头单药治疗对bDMARDs疗效不足或不耐受的活动性类风湿关节炎患者的疗效和安全性的随机、双盲、阳性对照的III期研究
[Translation] A randomized, double-blind, active-controlled phase III study to evaluate the efficacy and safety of TLL-018 versus tofacitinib monotherapy in patients with active rheumatoid arthritis who have insufficient efficacy or intolerance to bDMARDs
100 Clinical Results associated with Girocitinib
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100 Translational Medicine associated with Girocitinib
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100 Patents (Medical) associated with Girocitinib
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100 Deals associated with Girocitinib
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Inflammation | NDA/BLA | US | 26 Jan 2020 | |
| Chronic Urticaria | Phase 3 | CN | 19 Mar 2024 | |
| Rheumatoid Arthritis | Phase 3 | CN | 14 Nov 2023 | |
| Plaque psoriasis | Phase 2 | US | 19 Jan 2023 | |
| Psoriasis | Phase 2 | CN | - | |
| Dermatitis, Atopic | Phase 1 | CN | 10 Jul 2023 | |
| Systemic Lupus Erythematosus | IND Approval | CN | 21 Aug 2023 | |
| Colitis, Ulcerative | Discovery | US | 30 Dec 2022 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
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NCT05133297 (EULAR2023) Manual  | Phase 2 | 101 | (gaadniulni) = nlsndochfr seplbcwcvc (mpwitgegzr, 28.42 - 67.58) View more | Positive | 31 May 2023 | ||
(gaadniulni) = jhccviwuyp seplbcwcvc (mpwitgegzr, 47.10 - 83.67) View more |
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