Drug Type Small molecule drug |
Synonyms Cinaciguat (JAN/INN), BAY-582667 |
Target |
Mechanism sGC stimulants(Soluble guanylate cyclase stimulants) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC36H39NO5 |
InChIKeyWPYWMXNXEZFMAK-UHFFFAOYSA-N |
CAS Registry329773-35-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D07577 | Cinaciguat | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute decompensated heart failure | Phase 2 | US | 01 Mar 2010 | |
Acute decompensated heart failure | Phase 2 | AR | 01 Mar 2010 | |
Acute decompensated heart failure | Phase 2 | AT | 01 Mar 2010 | |
Acute decompensated heart failure | Phase 2 | BE | 01 Mar 2010 | |
Acute decompensated heart failure | Phase 2 | FR | 01 Mar 2010 | |
Acute decompensated heart failure | Phase 2 | DE | 01 Mar 2010 | |
Acute decompensated heart failure | Phase 2 | IE | 01 Mar 2010 | |
Acute decompensated heart failure | Phase 2 | MX | 01 Mar 2010 | |
Acute decompensated heart failure | Phase 2 | PH | 01 Mar 2010 | |
Decompensated chronic heart failure | Phase 2 | US | 01 Dec 2007 |
Phase 2 | 139 | dcopcnluys(xylbpgsjat) = the trial was stopped prematurely due to an increased occurrence of hypotension at cinaciguat doses ≥200 µg/h yyovydxqji (krizpumopq ) | - | 01 Jan 2013 | |||
Placebo | |||||||
Not Applicable | - | hbbhyzzjdn(piysxldlwp) = upaymshgec rpzdrgwboc (wgdwpccjgs ) | - | 01 May 2012 | |||
Diabetic + Cinaciguat treatment | hbbhyzzjdn(piysxldlwp) = qkwjxyqxun rpzdrgwboc (wgdwpccjgs ) |